Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: cell population proliferation Molecular Function: metal ion binding
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
Shh
(Mus musculus)Gene
Name: sonic hedgehog
Synonyms: hedgehog gene 1, Dsh, Hhg1, short digits, ShhNC
Source: MGI:98297
Biotype: protein coding gene
TYR
(Homo sapiens)Gene
Name: tyrosinase
Synonyms: SHEP3, OCA1, tumor rejection antigen AB, LB24-AB, SK29-AB, OCA1A, oculocutaneous albinism IA, CMM8, ATN, OCAIA, monophenol monooxygenase
Source: HGNC:12442
Biotype: protein coding gene
Kit
(Mus musculus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Dominant white spotting, gsf spotted coat 1, Fdc, c-KIT, Gsfsco1, dominant spotting, Ssm, gsf spotted coat 5, SCO5, Bs, SCO1, Tr-kit, W, CD117, spotted sterile male, Steel Factor Receptor, Gsfsow3, Gsfsco5, phenotype like Sl or W 3, belly-spot, SOW3
Source: MGI:96677
Biotype: protein coding gene
FGFR3
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 3
Synonyms: tyrosine kinase JTK4, JTK4, HSFGFR3EX, ACH, CEK2, fibroblast growth factor receptor 3 variant 4, achondroplasia, thanatophoric dwarfism, CD333, fibroblast growth factor receptor 3-S, hydroxyaryl-protein kinase, FGFR-3
Source: HGNC:3690
Biotype: protein coding gene
MRE11
(Homo sapiens)Gene
Name: MRE11 homolog, double strand break repair nuclease
Synonyms: HNGS1, double-strand break repair protein MRE11A, MRE11 homolog A, DNA recombination and repair protein, MRE11A, MRE11B, endo/exonuclease Mre11, meiotic recombination 11 homolog A, double-strand break repair protein MRE11, MRE11 meiotic recombination 11-like protein A, MRE11 homolog A, double strand break repair nuclease, MRE11 meiotic recombination 11 homolog A, ATLD, AT-like disease, MRE11 homolog 1, MRE11 double strand break repair nuclease A, MRE11 homolog, double strand break repair nuclease A, meiotic recombination 11 homolog 1
Source: HGNC:7230
Biotype: protein coding gene
ACE
(Homo sapiens)Gene
Name: angiotensin I converting enzyme
Synonyms: CD143, dipeptidyl carboxypeptidase I, CD143 antigen, angiotensin 1 converting enzyme 1, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, testicular ECA, MGC26566, MVCD3, kininase II, peptidase P, ICH, DCP, ACE1, carboxycathepsin, dipeptidyl carboxypeptidase 1, angiotensin converting enzyme, somatic isoform, angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript, DCP1, angiotensin-converting enzyme
Source: HGNC:2707
Biotype: protein coding gene
Cdkn1a
(Mus musculus)Gene
Name: cyclin dependent kinase inhibitor 1A
Synonyms: CDKI, Cip1, p21Cip1, P21, Cdkn1, p21, cyclin dependent kinase inhibitor, CIP1, UV96, p21WAF, Waf1, CAP20, SDI1, mda6
Source: MGI:104556
Biotype: protein coding gene
Hprt1
(Mus musculus)Gene
Name: hypoxanthine phosphoribosyltransferase 1
Synonyms: Hgprtase, expressed sequence C81579, hypoxanthine guanine phosphoribosyl transferase, Hprt, C81579, hypoxanthine guanine phosphoribosyl transferase 1
Source: MGI:96217
Biotype: protein coding gene
shha
(Danio rerio)Gene
Name: sonic hedgehog signaling molecule a
Synonyms: shh, vertebrate hedgehog homolog, sonic you, sonic-you, vhh1, fc83d08, syu, wu:fc83d08
Source: ZFIN:ZDB-GENE-980526-166
Biotype: protein coding gene
ERCC2
(Homo sapiens)Gene
Name: ERCC excision repair 2, TFIIH core complex helicase subunit
Synonyms: general transcription and DNA repair factor IIH helicase subunit XPD, TTD, TFIIH basal transcription factor complex 80 kDa subunit, TTD1, TFIIH basal transcription factor complex helicase subunit, COFS2, DNA 5'-3' helicase XPD, XPD, EM9, excision repair cross-complementing rodent repair deficiency, complementation group 2, xeroderma pigmentosum complementary group D, xeroderma pigmentosum group D-complementing protein, BTF2 p80, basic transcription factor 2 80 kDa subunit, trichothiodystrophy, MGC102762, MGC126218, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex helicase XPB subunit, MGC126219, excision repair cross-complementation group 2, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH subunit XPD, TFIIH, CXPD, TFIIH p80, TFIIH 80 kDa subunit, DNA excision repair protein ERCC-2
Source: HGNC:3434
Biotype: protein coding gene
KIT
(Homo sapiens)Gene
Name: KIT proto-oncogene, receptor tyrosine kinase
Synonyms: tyrosine-protein kinase Kit, proto-oncogene c-Kit, PBT, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein, piebald trait protein, piebald trait, p145 c-kit, c-Kit protooncogene, C-Kit, soluble KIT variant 1, KIT proto-oncogene receptor tyrosine kinase, mast/stem cell growth factor receptor, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, mast/stem cell growth factor receptor Kit, MASTC, CD117, SCFR, proto-oncogene tyrosine-protein kinase Kit
Source: HGNC:6342
Biotype: protein coding gene
ESR1
(Homo sapiens)Gene
Name: estrogen receptor 1
Synonyms: estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha 3*,4,5,6,7*/822 isoform, estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform, oestrogen receptor alpha, estrogen receptor alpha splice variant, ERalphai67, nuclear receptor subfamily 3 group A member 1, NR3A1, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform, ESTRR, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, ERalphaDup5, estradiol receptor, ESR, estrogen receptor, E2 receptor alpha, estrogen receptor alpha splice variant, ERalphai45bL, estrogen nuclear receptor alpha, estrogen receptor alpha splice variant, ERalphai56, ER, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bS, Era, estrogen receptor alpha delta 4*,5,6,7*/654 isoform, estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform, ESRA, ER-alpha, DKFZp686N23123
Source: HGNC:3467
Biotype: protein coding gene
SP2
(Homo sapiens)Gene
Name: Sp2 transcription factor
Synonyms: transcription factor Sp2
Source: HGNC:11207
Biotype: protein coding gene
Tyr
(Mus musculus)Gene
Name: tyrosinase
Synonyms: skin/coat color 35, Oca1, c, albino, skc35
Source: MGI:98880
Biotype: protein coding gene
N
(Drosophila melanogaster)Gene
Name: Notch
Synonyms: 16-178, 16-55, RICN, Abruptex, Chp, Co, EG:163A10.2, Confluens, split, anon-EST:Liang-1.12, Ax, dNotch, Nicd, Chopped, Notch, NOTCH, strawberry, clone 1.12, co, spl, shd, 1.1, nd, l(1)3Cb, NICD, CG3936, notchoid, n[fah], notch, fa, NECD, CT13012, EG:140G11.1, facet, l(1)Ax, l(1)N, swb
Source: FB:FBgn0004647
Biotype: protein coding gene
Foxp2
(Mus musculus)Gene
Name: forkhead box P2
Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, expressed sequence AI449000, AI449000, D0Kist7, DNA segment, KIST 7
Source: MGI:2148705
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, PPARG2, peroxisome proliferator-activated receptor-gamma 5, CIMT1, PPARG5, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
STK11
(Homo sapiens)Gene
Name: serine/threonine kinase 11
Synonyms: serine/threonine-protein kinase STK11, polarization-related protein LKB1, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11 (peutz-jeghers syndrome), liver kinase B1, serine/threonine-protein kinase 11, PJS, serine/threonine-protein kinase LKB1, hLKB1, LKB1
Source: HGNC:11389
Biotype: protein coding gene
SHH
(Homo sapiens)Gene
Name: sonic hedgehog signaling molecule
Synonyms: HLP3, HPE3, sonic hedgehog, TPT, ShhNC, sonic hedgehog homolog, HHG1, MCOPCB5, SMMCI, sonic hedgehog protein, shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, TPTPS
Source: HGNC:10848
Biotype: protein coding gene
NOTCH1
(Homo sapiens)Gene
Name: notch receptor 1
Synonyms: notch 1, translocation-associated notch protein TAN-1, TAN1, neurogenic locus notch homolog protein 1, notch gene homolog 1, (drosophila), hN1, Notch homolog 1, translocation-associated, AOVD1, AOS5
Source: HGNC:7881
Biotype: protein coding gene
Rora
(Mus musculus)Gene
Name: RAR-related orphan receptor alpha
Synonyms: neuroscience mutagenesis facility, 267, Tennessee Mouse Genome Consortium 26, sg, RIKEN cDNA 9530021D13 gene, Nr1f1, nmf267, 9530021D13Rik, staggerer, tmgc26
Source: MGI:104661
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Itgam
(Mus musculus)Gene
Name: integrin alpha M
Synonyms: complement receptor type 3, macrophage antigen alpha chain (integrin), F730045J24Rik, CR3, lymphocyte antigen 40, Mac-1a, CD11B (p170), Mac-1 alpha, complement component receptor 3 alpha, CD11b/CD18, Mac-1, Ly-40, RIKEN cDNA F730045J24 gene, Cd11b
Source: MGI:96607
Biotype: protein coding gene
FOXP2
(Homo sapiens)Gene
Name: forkhead box P2
Synonyms: forkhead box protein P2, TNRC10, CAGH44, trinucleotide repeat-containing gene 10 protein, CAG repeat protein 44, DKFZp686H1726, forkhead/winged-helix transcription factor, SPCH1, trinucleotide repeat containing 10
Source: HGNC:13875
Biotype: protein coding gene
Itgb1
(Mus musculus)Gene
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: Gm9863, fibronectin receptor beta (integrin), expressed sequence AA960159, AA409975, 4633401G24Rik, expressed sequence AA409975, beta1 integrin, ENSMUSG00000051907, RIKEN cDNA 4633401G24 gene, AA960159, CD29, Fnrb, predicted gene 9863, predicted gene, ENSMUSG00000051907
Source: MGI:96610
Biotype: protein coding gene
Gata3
(Mus musculus)Gene
Name: GATA binding protein 3
Synonyms: juvenile alopecia, jal, Gata-3
Source: MGI:95663
Biotype: protein coding gene
Gli3
(Mus musculus)Gene
Name: GLI-Kruppel family member GLI3
Synonyms: add, anterior digit pattern deformity, expressed sequence AI854843, extra toes, brachyphalangy, polydactyly Nagoya, AU023367, expressed sequence AU023367, Pdn, Bph, Xt, AI854843
Source: MGI:95729
Biotype: protein coding gene
tp53
(Danio rerio)Gene
Name: tumor protein p53
Synonyms: etID22686.5, brp53, drp53, fb40d06, zgc:111919, p53, wu:fb40d06
Source: ZFIN:ZDB-GENE-990415-270
Biotype: protein coding gene
Glul
(Mus musculus)Gene
Name: glutamate-ammonia ligase
Synonyms: glutamine synthetase, Glns, GS
Source: MGI:95739
Biotype: protein coding gene
Gata4
(Mus musculus)Gene
Name: GATA binding protein 4
Synonyms: Gata-4
Source: MGI:95664
Biotype: protein coding gene
Fyn
(Mus musculus)Gene
Name: Fyn proto-oncogene
Synonyms: expressed sequence AW552119, AW552119, AI448320, Src Kinase p59, expressed sequence AI448320
Source: MGI:95602
Biotype: protein coding gene
myl7
(Danio rerio)Gene
Name: myosin, light chain 7, regulatory
Synonyms: mlc7, tell tale heart, cmlc2, zgc:92755, mylc2a, tel
Source: ZFIN:ZDB-GENE-991019-3
Biotype: protein coding gene
RUNX1
(Homo sapiens)Gene
Name: RUNX family transcription factor 1
Synonyms: acute myeloid leukemia 1 protein, AML1-EVI-1, mutant RUNX1, EVI-1, AML1-EVI-1 fusion protein, PEBP2aB, AMLCR1, oncogene AML-1, PEBP2alpha, AML1, SL3-3 enhancer factor 1 alpha B subunit, PEBP2-alpha B, SL3/AKV core-binding factor alpha B subunit, runt related transcription factor 1, CBF2alpha, CBFA2, core-binding factor, runt domain, alpha subunit 2, PEA2-alpha B, runt-related transcription factor 1, polyomavirus enhancer-binding protein 2 alpha B subunit, AML1-ETO fusion
Source: HGNC:10471
Biotype: protein coding gene
Rere
(Mus musculus)Gene
Name: arginine glutamic acid dipeptide (RE) repeats
Synonyms: RIKEN cDNA 1110033A15 gene, eye, 1110033A15Rik, mKIAA0458, eyes 3, expressed sequence AW742570, atrophin-2, Atr2, expressed sequence AI414665, eye03, eyes3, AW742570, AI414665, Arp
Source: MGI:2683486
Biotype: protein coding gene
Enpep
(Mus musculus)Gene
Name: glutamyl aminopeptidase
Synonyms: APA, Bp-1/6C3, RIKEN cDNA 6030431M22 gene, lymphocyte antigen 51, aminopeptidase-A, 6030431M22Rik, Ly-51, Ly51
Source: MGI:106645
Biotype: protein coding gene
PRKCA
(Homo sapiens)Gene
Name: protein kinase C alpha
Synonyms: AAG6, PKC-A, PKCI+/-, MGC129901, MGC129900, PKCalpha, PKC-alpha, PKCA, PRKACA, aging-associated gene 6, protein kinase C alpha type
Source: HGNC:9393
Biotype: protein coding gene
Raf1
(Mus musculus)Gene
Name: v-raf-leukemia viral oncogene 1
Synonyms: 6430402F14Rik, c-Raf, expressed sequence AA990557, Raf-1, Craf1 transforming gene, sarcoma 3611 oncogene, v-Raf, expressed sequence BB129353, AA990557, BB129353, Craf1, murine sarcoma 3611 oncogene 1, RIKEN cDNA 6430402F14 gene
Source: MGI:97847
Biotype: protein coding gene
FGFR2
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 2
Synonyms: FLJ98662, fibroblast growth factor receptor 2 Ksam IV secreted isoform, K-SAM, KGFR, FGFR-2, CFD1, keratinocyte growth factor receptor, BBDS, BEK fibroblast growth factor receptor, ECT1, bacteria-expressed kinase, TK25, CD332, FGF receptor, fibroblast growth factor receptor 2 isoform IgIIIc isoform, JWS, fibroblast growth factor receptor 2 isoform IgIIIb isoform, BEK, hydroxyaryl-protein kinase, BFR-1, protein tyrosine kinase, receptor like 14, CEK3, soluble FGFR4 variant 4, TK14, FGFR2-AHCYL1 fusion kinase protein, fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
Source: HGNC:3689
Biotype: protein coding gene
B4galt1
(Mus musculus)Gene
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Synonyms: B-1,4-GalT1, AA407245, GalT, beta 1,4-Galactosyltransferase I, b1,4-Galactosyltransferase I, beta-1,4-GalT1, glycoprotein galactosyltransferase beta 1, 4, Ggtb2, galactosyltransferase 2 beta 1, 4, Ggtb, expressed sequence AA407245
Source: MGI:95705
Biotype: protein coding gene
Kit
(Rattus norvegicus)Gene
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: Kit oncogene, mast/stem cell growth factor receptor, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, mast/stem cell growth factor receptor Kit, c-kit receptor tyrosine kinase, protein kinase
Source: RGD:620568
Biotype: protein coding gene
KMT2A
(Homo sapiens)Gene
Name: lysine methyltransferase 2A
Synonyms: MLL-AF9, HTRX1, mixed lineage leukemia 1, TET1-MLL, histone-lysine N-methyltransferase MLL, CDK6/MLL fusion protein, zinc finger protein HRX, MLL, myeloid/lymphoid or mixed-lineage leukemia protein 1, ALL1, CXXC7, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), WDSTS, HRX, MLL/GAS7 fusion protein, ALL-1, CXXC-type zinc finger protein 7, MLL-AF4 der(11) fusion protein, MLL/GAS7, lysine N-methyltransferase 2A, MLL1A, lysine (K)-specific methyltransferase 2A, MLL1, hypothetical protein FLJ11783, Acute lymphocytic 1, histone-lysine N-methyltransferase 2A, HTRX, TRX1, FLJ11783, trithorax-like protein, MLL/GMPS fusion protein, GAS7
Source: HGNC:7132
Biotype: protein coding gene
Ada
(Mus musculus)Gene
Name: adenosine deaminase
Synonyms: Not Available
Source: MGI:87916
Biotype: protein coding gene
SMAD4
(Homo sapiens)Gene
Name: SMAD family member 4
Synonyms: hSMAD4, deleted in pancreatic carcinoma locus 4, MADH4, MAD homolog 4, mothers against decapentaplegic homolog 4, SMAD 4, mothers against DPP homolog 4, deletion target in pancreatic carcinoma 4, JIP, MAD, mothers against decapentaplegic homolog 4, mothers against decapentaplegic, Drosophila, homolog of, 4, smad, mothers against dpp homolog 4 (drosophila), MYHRS, DPC4, SMAD, mothers against DPP homolog 4
Source: HGNC:6770
Biotype: protein coding gene
Egr1
(Mus musculus)Gene
Name: early growth response 1
Synonyms: Ngf1, Krox-1, Zenk, zinc finger protein 6, Krox24, Kruppel box 24, Egr-1, NGFIA, zif-268, Zfp-6, Krox-24, Kruppel box 1, NGFI-A, ETR103, RIKEN cDNA A530045N19 gene, Zif268, Ngfi, A530045N19Rik, NGF1-A, TIS8
Source: MGI:95295
Biotype: protein coding gene
ADA
(Homo sapiens)Gene
Name: adenosine deaminase
Synonyms: ADA1, adenosine aminohydrolase, mutant adenosine deaminase
Source: HGNC:186
Biotype: protein coding gene