Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: negative regulation of transforming growth factor beta receptor signaling pathway
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, p53 transformation suppressor, antigen NY-CO-13, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, FLJ92943, TRP53, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, p53 tumor suppressor, BMFS5, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, regulatory protein SIR2 homolog 1, hSIRT1, hSIR2, sirtuin type 1, NAD-dependent deacetylase sirtuin-1
Source: HGNC:14929
Biotype: protein coding gene
HSPA1A
(Homo sapiens)Gene
Name: heat shock protein family A (Hsp70) member 1A
Synonyms: HSP70-2, HSP70-1, epididymis secretory protein Li 103, HSP70-1A, FLJ54303, FLJ75127, FLJ54408, heat shock 70kD protein 1A, heat shock 70 kDa protein 1/2, HSP70.1/HSP70.2, HSP70I, heat shock-induced protein, HSP72, dnaK-type molecular chaperone HSP70-1, HSP70.2, HSP70.1, HSP70, heat shock 70 kDa protein 1A, Heat shock 70 kDa protein 1B, HEL-S-103, HSPA1, heat shock 70kDa protein 1A, HSP70-1/HSP70-2, Heat shock 70 kDa protein 2, heat shock 70 kDa protein 1A/1B, heat shock 70 kDa protein 1, FLJ54392, FLJ54370, heat shock protein family A member 1A, HSPA1B
Source: HGNC:5232
Biotype: protein coding gene
FBN1
(Homo sapiens)Gene
Name: fibrillin 1
Synonyms: ACMICD, OCTD, fibrillin-1 preproprotein, MFLS, fibrillin 15, asprosin, Weill-Marchesani syndrome, ECTOL1, fibrillin-1, SSKS, MFS1, FBN, MASS, GPHYSD2, WMS, WMS2, SGS
Source: HGNC:3603
Biotype: protein coding gene
PPARG
(Homo sapiens)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: peroxisome proliferator-activated receptor-gamma splicing, peroxisome proliferator activated receptor, gamma, GLM1, PPARgamma, NR1C3, PPAR gamma, PPAR-gamma, PPARG1, peroxisome proliferator-activated receptor gamma 1, PPARG2, peroxisome proliferator-activated receptor-gamma 5, CIMT1, PPARG5, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, nuclear receptor subfamily 1 group C member 3
Source: HGNC:9236
Biotype: protein coding gene
Fbn1
(Mus musculus)Gene
Name: fibrillin 1
Synonyms: expressed sequence AI536462, Fib-1, tight skin, AI536462, Tsk
Source: MGI:95489
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
HSPA5
(Homo sapiens)Gene
Name: heat shock protein family A (Hsp70) member 5
Synonyms: endoplasmic reticulum chaperone BiP, heat shock 70kd protein 5, glucose-regulated protein, 78kDa, FLJ26106, heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), HSP70 family protein 5, GRP78, BIP, Heat-shock 70kD protein-5 (glucose-regulated protein, 78kD), MIF2, 78 kDa glucose-regulated protein, HEL-S-89n, heat shock 70 kDa protein 5, epididymis secretory sperm binding protein Li 89n, endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock protein 70 family protein 5, immunoglobulin heavy chain-binding protein, GRP-78, heat shock protein family A member 5, glucose-regulated protein, 78-kD
Source: HGNC:5238
Biotype: protein coding gene
Xbp1
(Mus musculus)Gene
Name: X-box binding protein 1
Synonyms: D11Ertd39e, TREB-5, HTF, DNA segment, Chr 11, ERATO Doi 39, expressed, TREB5, XBP-1
Source: MGI:98970
Biotype: protein coding gene
Tp53
(Rattus norvegicus)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor protein p53 (Li-Fraumeni syndrome), Trp53, tumor suppressor p53, transformation related protein 53, MGC112612, p53
Source: RGD:3889
Biotype: protein coding gene
Sirt1
(Mus musculus)Gene
Name: sirtuin 1
Synonyms: Sir2, expressed sequence AA673258, AA673258, Sir2alpha
Source: MGI:2135607
Biotype: protein coding gene
HSPA1B
(Homo sapiens)Gene
Name: heat shock protein family A (Hsp70) member 1B
Synonyms: HSP70-2, HSP70.2, HSP70-1, HSP70.1, FLJ54328, heat shock 70 kDa protein 1B, Heat shock 70 kDa protein 1A, HSPA1, heat shock 70kD protein 1B, HSP70-1/HSP70-2, heat shock 70kDa protein 1B, heat shock 70 kDa protein 1A/1B, heat shock 70 kDa protein 2, Heat shock 70 kDa protein 1, heat shock 70 kDa protein 1/2, HSP70.1/HSP70.2, heat shock 70kd protein 1a, HSX70, HSP70-1B, heat shock protein family A member 1B, HSP72, HSPA1A
Source: HGNC:5233
Biotype: protein coding gene
Bmp2
(Mus musculus)Gene
Name: bone morphogenetic protein 2
Synonyms: AI467020, bone morphogenetic protein 2a, Bmp2a, expressed sequence AI467020
Source: MGI:88177
Biotype: protein coding gene
Arid4a
(Mus musculus)Gene
Name: AT-rich interaction domain 4A
Synonyms: Rbbp1, A630067N03Rik, retinoblastoma binding protein 1, RIKEN cDNA A630067N03 gene
Source: MGI:2444354
Biotype: protein coding gene
LDLRAD4
(Homo sapiens)Gene
Name: low density lipoprotein receptor class A domain containing 4
Synonyms: C18orf1, low-density lipoprotein receptor class A domain-containing protein 4, uncharacterized protein C18orf1, clone 22, hypothetical protein LOC753
Source: HGNC:1224
Biotype: protein coding gene
Smad7
(Mus musculus)Gene
Name: SMAD family member 7
Synonyms: Madh7
Source: MGI:1100518
Biotype: protein coding gene
RBBP4
(Homo sapiens)Gene
Name: RB binding protein 4, chromatin remodeling factor
Synonyms: nucleosome-remodeling factor subunit RBAP48, CAF-I 48 kDa subunit, RBBP-4, chromatin assembly factor/CAF-1 p48 subunit, RBAP48, chromatin assembly factor I p48 subunit, MSI1 protein homolog, retinoblastoma-binding protein 4, CAF-I p48, histone-binding protein RBBP4, retinoblastoma-binding protein p48, retinoblastoma binding protein 4, NURF55, chromatin assembly factor 1 subunit C, CAF-1 subunit C, lin-53
Source: HGNC:9887
Biotype: protein coding gene
MECOM
(Homo sapiens)Gene
Name: MDS1 and EVI1 complex locus
Synonyms: zinc finger protein Evi1, AML1-EVI-1, PRDM3, ecotropic virus integration site 1 protein homolog, AML1-EVI-1 fusion protein, PR domain 3, MGC97004, myelodysplasia syndrome-associated protein 1, RUSAT2, oncogene EVI1, histone-lysine N-methyltransferase MECOM, MDS1, MDS1-EVI1, ecotropic viral integration site 1, EVI1, KMT8E, myelodysplasia syndrome 1, myelodysplasia syndrome 1 protein, MDS1 and EVI1 complex locus protein EVI1, MDS1 and EVI1 complex locus protein MDS1, MGC163392
Source: HGNC:3498
Biotype: protein coding gene
ADAM17
(Homo sapiens)Gene
Name: ADAM metallopeptidase domain 17
Synonyms: ADAM 17, cartilage snake venom-like protease, a disintegrin and metalloproteinase domain 17, snake venom-like protease, TACE, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase 17, TNF-alpha converting enzyme, TNF-alpha convertase, ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM18, NISBD1, MGC71942, disintegrin and metalloproteinase domain-containing protein 17, TNF-alpha convertase enzyme, ADAM metallopeptidase domain 18, CSVP, NISBD, tumor necrosis factor, alpha, converting enzyme, CD156B
Source: HGNC:195
Biotype: protein coding gene
GDF15
(Homo sapiens)Gene
Name: growth differentiation factor 15
Synonyms: PTGF-beta, NSAID-regulated gene 1 protein, placental TGF-beta, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1, prostate differentiation factor, placental bone morphogenetic protein, GDF-15, MIC1, macrophage inhibitory cytokine 1, non-steroidal anti-inflammatory drug-activated gene-1, NAG-1, PTGFB, PDF, MIC-1, NRG-1, PLAB, NSAID-activated gene 1 protein, growth/differentiation factor 15, HG
Source: HGNC:30142
Biotype: protein coding gene
STRAP
(Homo sapiens)Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: MAWD, MAPK activator with WD repeats, UNRIP, mitogen-activated protein kinase activator with WD repeats, unr-interacting protein, MAP activator with WD repeats, PT-WD, serine-threonine kinase receptor-associated protein, WD-40 repeat protein PT-WD
Source: HGNC:30796
Biotype: protein coding gene
Dnm2
(Mus musculus)Gene
Name: dynamin 2
Synonyms: DYIIAAB, Mutant line 2159, b2b2159Clo, Dyn2
Source: MGI:109547
Biotype: protein coding gene
Lrp1
(Mus musculus)Gene
Name: low density lipoprotein receptor-related protein 1
Synonyms: Mutant line 1554, b2b1554Clo, alpha-2-macroglobulin receptor, AI316852, CD91, expressed sequence AI316852, A2mr, LRP-1
Source: MGI:96828
Biotype: protein coding gene
PMEPA1
(Homo sapiens)Gene
Name: prostate transmembrane protein, androgen induced 1
Synonyms: solid tumor-associated gene 1, prostate transmembrane protein androgen induced 1, STAG1, transmembrane prostate androgen-induced protein, transmembrane, prostate androgen induced RNA, TMEPAI, solid tumor-associated 1 protein
Source: HGNC:14107
Biotype: protein coding gene
ENG
(Homo sapiens)Gene
Name: endoglin
Synonyms: FLJ41744, ORW, ORW1, END, CD105, HHT1, soluble endoglin, CD105 antigen
Source: HGNC:3349
Biotype: protein coding gene
Hspa5
(Mus musculus)Gene
Name: heat shock protein 5
Synonyms: glucose-regulated protein (78 kDa), AU019543, 78kDa, DNA segment, Chr 2, Wayne State University 141, expressed, GRP78, Bip, BIP, Sez7, D2Wsu141e, AL022860, GRP 78, mBiP, expressed sequence AU019543, XAP-1 antigen, D2Wsu17e, Grp78, Hsce70, baffled, glucose regulated protein, 78 kDa, expressed sequence AL022860, DNA segment, Chr 2, Wayne State University 17, expressed
Source: MGI:95835
Biotype: protein coding gene
Peg10
(Mus musculus)Gene
Name: paternally expressed 10
Synonyms: Mar2, Edr, EST AA407948, Mart2, AA407948, MEF3L, MyEF-3 like, MyEF-3, Rtl2, HB-1
Source: MGI:2157785
Biotype: protein coding gene
OGT
(Homo sapiens)Gene
Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Synonyms: O-linked N-acetylglucosamine transferase 110 kDa subunit, o linked n-acetylglucosamine transferase, MGC22921, FLJ23071, OGT1, O-GlcNAc transferase p110 subunit, O-GlcNAc transferase subunit p110, XLID106, HINCUT-1, O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase), MRX106, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, uridinediphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyl transferase, O-GLCNAC, HRNT1, UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase
Source: HGNC:8127
Biotype: protein coding gene
PDPK1
(Homo sapiens)Gene
Name: 3-phosphoinositide dependent protein kinase 1
Synonyms: 3-phosphoinositide-dependent protein kinase 1, PRO0461, PDPK2, MGC20087, PDPK2P, Putative 3-phosphoinositide-dependent protein kinase 2, MGC35290, 3-phosphoinositide-dependent protein kinase 2 pseudogene, PkB-like 1, 3-phosphoinositide dependent protein kinase-1, hPDK1, PkB kinase like gene 1, PDK1
Source: HGNC:8816
Biotype: protein coding gene
MIR27B
(Homo sapiens)Gene
Name: microRNA 27b
Synonyms: miRNA27B, MIR-27b, MIRN27B
Source: HGNC:31614
Biotype: ncRNA gene
HDAC1
(Homo sapiens)Gene
Name: histone deacetylase 1
Synonyms: GON-10, HD1, RPD3L1, KDAC1, DKFZp686H12203, RPD3, reduced potassium dependency, yeast homolog-like 1
Source: HGNC:4852
Biotype: protein coding gene
egl-4
(Caenorhabditis elegans)Gene
Name: EGg Laying defective 4
Synonyms: odr-9, chb-1, CELE_F55A8.2, cgk-1, F55A8.g, F55A8.e, F55A8.f, pkg-1, F55A8.d, F55A8.b, eat-7, F55A8.2
Source: WB:WBGene00001173
Biotype: protein coding gene
Ppm1a
(Rattus norvegicus)Gene
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1A
Synonyms: Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform, PP2C-alpha, MGC114340, protein phosphatase 1A, IA, protein phosphatase 1A, magnesium dependent, alpha isoform, Pp2c1, protein phosphatase 2C isoform alpha, Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform, protein phosphatase IA
Source: RGD:3373
Biotype: protein coding gene
Ppara
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor alpha
Synonyms: PPARalpha, AI118064, Nr1c1, PPAR, expressed sequence AW742785, 4933429D07Rik, PPAR-alpha, peroxisome proliferator activated receptor, expressed sequence AI118064, Ppar, RIKEN cDNA 4933429D07 gene, AW742785
Source: MGI:104740
Biotype: protein coding gene
Adam17
(Mus musculus)Gene
Name: a disintegrin and metallopeptidase domain 17
Synonyms: Tace, TACE, CD156b, tumor necrosis factor-alpha converting enzyme
Source: MGI:1096335
Biotype: protein coding gene
Ogt
(Mus musculus)Gene
Name: O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Synonyms: RIKEN cDNA 1110038P24 gene, 4831420N21Rik, O linked N-acetylglucosamine transferase like, 1110038P24Rik, expressed sequence AI115525, Ogtl, AI115525, O linked N-acetylgulucosamine transferase like, OGT, RIKEN cDNA 4831420N21 gene
Source: MGI:1339639
Biotype: protein coding gene
Pparg
(Rattus norvegicus)Gene
Name: peroxisome proliferator-activated receptor gamma
Synonyms: peroxisome proliferator activator receptor, gamma, PPARgamma2, peroxisome proliferator activator receptor gamma, peroxisome proliferator activated receptor, gamma, peroxisome proliferator activated receptor gamma, PPAR-gamma, nuclear receptor subfamily 1 group C member 3
Source: RGD:3371
Biotype: protein coding gene
bambia
(Danio rerio)Gene
Name: BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
Synonyms: Zfnma, wu:fe01e03, nma, wu:fc44c12, fc44c12, bambi, id:ibd5020, cb998, etID64300.12
Source: ZFIN:ZDB-GENE-010416-1
Biotype: protein coding gene
Spred1
(Mus musculus)Gene
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, AW047647, RIKEN cDNA 5730461F13 gene, 5730461F13Rik, AL024345, expressed sequence AW047647, expressed sequence AL024345
Source: MGI:2150016
Biotype: protein coding gene
FKBP1A
(Homo sapiens)Gene
Name: FKBP prolyl isomerase 1A
Synonyms: FKBP1, FK506 binding protein 1A, 12kDa, peptidyl-prolyl cis-trans isomerase FKBP1A, PKC12, rotamase, FKBP12, FK506 binding protein12, 12 kDa FKBP, FK506 binding protein 1A, PPIase FKBP1A, FK506-binding protein, T-cell, 12-kD, FKBP-1A, FK506-binding protein 1, 12 kDa FK506-binding protein, calstabin-1, immunophilin FKBP12, FKBP12-Exip3, PPIASE, FKBP-12, FK506-binding protein 1A (12kD), fk506-binding protein 1a, FK506-binding protein 12, FKBP12C, PKCI2, calstabin 1, protein kinase C inhibitor 2
Source: HGNC:3711
Biotype: protein coding gene
Ldlrad4
(Mus musculus)Gene
Name: low density lipoprotein receptor class A domain containing 4
Synonyms: DNA segment, Chr 18, ERATO Doi 653, expressed, RIKEN cDNA 8230401C20 gene, D18Ertd653e, RIKEN cDNA A430108L08 gene, A430108L08Rik, RIKEN cDNA D330030L18 gene, 8230401C20Rik, D330030L18Rik
Source: MGI:1277150
Biotype: protein coding gene
GLG1
(Homo sapiens)Gene
Name: golgi glycoprotein 1
Synonyms: CFR-1, selectin, endothelial cell, ligand, DKFZp686L08213, FLJ32797, golgi sialoglycoprotein MG-160, Golgi apparatus protein 1, MG160, ESL-1, cysteine-rich fibroblast growth factor receptor, RP11-252A24.7, E-selectin ligand 1, MG-160, FLJ23319, FLJ23967
Source: HGNC:4316
Biotype: protein coding gene
Cilp
(Mus musculus)Gene
Name: cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Synonyms: C130036G17Rik, RIKEN cDNA C130036G17 gene
Source: MGI:2444507
Biotype: protein coding gene
NKX2-1
(Homo sapiens)Gene
Name: NK2 homeobox 1
Synonyms: NKX2A, NK-2, BCH, homeobox protein NK-2 homolog A, TITF1, NMTC1, TTF1, TTF-1, NK-2 homolog A, T/EBP, thyroid transcription factor 1, thyroid nuclear factor 1, homeobox protein Nkx-2.1, TEBP, NKX2.1, BHC
Source: HGNC:11825
Biotype: protein coding gene
Hspa5
(Rattus norvegicus)Gene
Name: heat shock protein family A (Hsp70) member 5
Synonyms: endoplasmic reticulum chaperone BiP, Heat shock 70kD protein 5, HSP70 family protein 5, GRP78, BIP, heat shock protein 5, GRP 78, 78 kDa glucose-regulated protein, heat shock 70 kDa protein 5, heat shock 70kDa protein 5 (glucose-regulated protein), steroidogenesis-activator polypeptide, immunoglobulin heavy chain-binding protein, heat shock protein 70 family protein 5, heat shock protein family A member 5, GRP-78
Source: RGD:2843
Biotype: protein coding gene
PBLD
(Homo sapiens)Gene
Name: phenazine biosynthesis like protein domain containing
Synonyms: MAWD-binding protein, epididymis secretory protein Li 306, MAWBP, phenazine biosynthesis-like domain-containing protein, HEL-S-306, FLJ14767, MAWD binding protein, FLJ35507, phenazine biosynthesis-like protein domain containing, MAWDBP
Source: HGNC:23301
Biotype: protein coding gene
Cav2
(Mus musculus)Gene
Name: caveolin 2
Synonyms: expressed sequence AI447843, AI447843
Source: MGI:107571
Biotype: protein coding gene
Ryr1
(Mus musculus)Gene
Name: ryanodine receptor 1, skeletal muscle
Synonyms: RYR-1, calcium release channel isoform 1, AI528790, expressed sequence AI528790, muscle ryanodine receptor, Ryr, Ryr1l, skrr
Source: MGI:99659
Biotype: protein coding gene
WNT1
(Homo sapiens)Gene
Name: Wnt family member 1
Synonyms: INT1, proto-oncogene Wnt-1, wingless-type MMTV integration site family, member 1 (oncogene INT1), BMND16, proto-oncogene Int-1 homolog, OI15, wingless-type MMTV integration site family member 1
Source: HGNC:12774
Biotype: protein coding gene