Version: 8.0.0Date: Tue Jan 28 2025
Gene Biological Process: regulation of G protein-coupled receptor signaling pathway
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide(1-42), beta-amyloid peptide, preA4, beta-amyloid peptide(1-40), cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, PARK4, alpha-synuclein, synuclein alpha-140, non-A4 component of amyloid, non A-beta component of AD amyloid, PD1
Source: HGNC:11138
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, Alzheimer disease amyloid beta protein, cerebrovascular amyloid peptide, protease nexin II, expressed sequence AL024401, AL024401, RIKEN cDNA E030013M08 gene, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
Fgf8
(Mus musculus)Gene
Name: fibroblast growth factor 8
Synonyms: androgen induced growth factor, Fgf6c, Aigf, Fgf-8
Source: MGI:99604
Biotype: protein coding gene
PRKCA
(Homo sapiens)Gene
Name: protein kinase C alpha
Synonyms: AAG6, PKC-A, PKCI+/-, MGC129901, MGC129900, PKCalpha, PKC-alpha, PKCA, PRKACA, aging-associated gene 6, protein kinase C alpha type
Source: HGNC:9393
Biotype: protein coding gene
F2
(Homo sapiens)Gene
Name: coagulation factor II, thrombin
Synonyms: thrombin factor II, RPRGL2, prothrombin B-chain, THPH1, PT, prepro-coagulation factor II, coagulation factor II, serine protease, coagulation factor II (thrombin), prothrombin
Source: HGNC:3535
Biotype: protein coding gene
Ulk4
(Mus musculus)Gene
Name: unc-51-like kinase 4
Synonyms: RIKEN cDNA 4932415A06 gene, 4932415A06Rik, RGD1565726
Source: MGI:1921622
Biotype: protein coding gene
ADA
(Homo sapiens)Gene
Name: adenosine deaminase
Synonyms: ADA1, adenosine aminohydrolase, mutant adenosine deaminase
Source: HGNC:186
Biotype: protein coding gene
FGF8
(Homo sapiens)Gene
Name: fibroblast growth factor 8
Synonyms: KAL6, androgen-induced growth factor, fibroblast growth factor 8 (androgen-induced), HBGF-8, HH6, heparin-binding growth factor 8, AIGF, MGC149376, FGF-8
Source: HGNC:3686
Biotype: protein coding gene
Itgb1
(Mus musculus)Gene
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: Gm9863, fibronectin receptor beta (integrin), expressed sequence AA960159, AA409975, 4633401G24Rik, expressed sequence AA409975, beta1 integrin, ENSMUSG00000051907, RIKEN cDNA 4633401G24 gene, AA960159, CD29, Fnrb, predicted gene 9863, predicted gene, ENSMUSG00000051907
Source: MGI:96610
Biotype: protein coding gene
LRRK2
(Homo sapiens)Gene
Name: leucine rich repeat kinase 2
Synonyms: RIPK7, leucine-rich repeat kinase 2, leucine-rich repeat serine/threonine-protein kinase 2, ROCO2, augmented in rheumatoid arthritis 17, AURA17, PARK8, DARDARIN, Parkinson disease (autosomal dominant) 8
Source: HGNC:18618
Biotype: protein coding gene
Snca
(Mus musculus)Gene
Name: synuclein, alpha
Synonyms: alpha-Syn, alphaSYN, alpha-synuclein
Source: MGI:1277151
Biotype: protein coding gene
Drd2
(Mus musculus)Gene
Name: dopamine receptor D2
Synonyms: D2R, Drd-2, D2 receptor
Source: MGI:94924
Biotype: protein coding gene
C3
(Homo sapiens)Gene
Name: complement C3
Synonyms: complement component 3, complement component C3, AHUS5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, HEL-S-62p, acylation-stimulating protein cleavage product, epididymis secretory sperm binding protein Li 62p, ARMD9, C3a anaphylatoxin, C3a, C3b, prepro-C3, CPAMD1, complement component C3b, complement component C3a, ASP
Source: HGNC:1318
Biotype: protein coding gene
Pde4
(Drosophila melanogaster)Gene
Name: Phosphodiesterase 4
Synonyms: CG10797, Dunce PDE, EG:BACN05I09.3, PDE4, dunce, EG:96G10.7, Dunce, EG:BACN5I9.2, PDE, EG:140G11.4, fs(1)M42, Dunce phosphodiesterase, PDEII, DNC, dnc, CG14267, Dnc, CG14268, phosphodiesterase, CG10791, CG32498, CG10792
Source: FB:FBgn0000479
Biotype: protein coding gene
Ppp3ca
(Mus musculus)Gene
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: AW413465, RIKEN cDNA 2900074D19 gene, AI841391, CN, calcineurin, Calna1, expressed sequence AW413465, 2900074D19Rik, CnA, expressed sequence AI841391, calcineurin, alpha subunit, Calna, PP2BA alpha, PP2B alpha 1, Caln
Source: MGI:107164
Biotype: protein coding gene
Ada
(Mus musculus)Gene
Name: adenosine deaminase
Synonyms: Not Available
Source: MGI:87916
Biotype: protein coding gene
Slit2
(Mus musculus)Gene
Name: slit guidance ligand 2
Synonyms: b2b1200.1Clo, RIKEN cDNA E030015M03 gene, Slil3, RIKEN cDNA E130320P19 gene, Drad-1, E130320P19Rik, E030015M03Rik, Mutant line 1200.1
Source: MGI:1315205
Biotype: protein coding gene
Lrrk2
(Mus musculus)Gene
Name: leucine-rich repeat kinase 2
Synonyms: cDNA sequence, clone 3-75, Gm927, RIKEN cDNA 4921513O20 gene, AW561911, RIKEN cDNA D630001M17 gene, RIKEN cDNA 9330188B09 gene, 4921513O20Rik, D630001M17Rik, LOC381026, gene model 927, (NCBI), cI-46, 9330188B09Rik
Source: MGI:1913975
Biotype: protein coding gene
Gper1
(Mus musculus)Gene
Name: G protein-coupled estrogen receptor 1
Synonyms: GPCR-Br, 6330420K13Rik, CMKRL2, RIKEN cDNA 6330420K13 gene, FEG-1, Gper, Ceprl, constitutively expressed peptide-like receptor like, GPR41, Gpr30, G protein-coupled receptor 30
Source: MGI:1924104
Biotype: protein coding gene
YWHAB
(Homo sapiens)Gene
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Synonyms: YWHAA, protein 1054, HS1, 14-3-3 protein beta/alpha, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide, protein kinase C inhibitor protein-1, KCIP-1, GW128, epididymis secretory protein Li 1, protein kinase C inhibitor protein 1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide, brain protein 14-3-3, beta isoform, 14-3-3 alpha, HEL-S-1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Source: HGNC:12849
Biotype: protein coding gene
C3
(Mus musculus)Gene
Name: complement component 3
Synonyms: AI255234, expressed sequence AI255234, complement factor 3, Plp, acylation stimulating protein
Source: MGI:88227
Biotype: protein coding gene
Ccl5
(Mus musculus)Gene
Name: C-C motif chemokine ligand 5
Synonyms: MuRantes, SISd, RANTES, TCP228, Rantes, small inducible cytokine A5, Scya5
Source: MGI:98262
Biotype: protein coding gene
Dnm1
(Mus musculus)Gene
Name: dynamin 1
Synonyms: fitful, Dnm, expressed sequence AI838169, AI838169, Ftfl
Source: MGI:107384
Biotype: protein coding gene
Dtnbp1
(Mus musculus)Gene
Name: dystrobrevin binding protein 1
Synonyms: AW048963, 5430437B18Rik, RIKEN cDNA 5430437B18 gene, sandy, Bloc1s8, sdy, dysbindin, expressed sequence AW048963
Source: MGI:2137586
Biotype: protein coding gene
CXCL8
(Homo sapiens)Gene
Name: C-X-C motif chemokine ligand 8
Synonyms: lymphocyte derived neutrophil activating peptide, lung giant cell carcinoma-derived chemotactic protein, tumor necrosis factor-induced gene 1, LYNAP, NAP-1, LECT, lymphocyte-derived neutrophil-activating factor, chemokine (C-X-C motif) ligand 8, interleukin-8, small inducible cytokine subfamily B, member 8, SCYB8, monocyte-derived neutrophil-activating peptide, GCP-1, beta endothelial cell-derived neutrophil activating peptide, T-cell chemotactic factor, neutrophil-activating peptide 1, LUCT, monocyte-derived neutrophil chemotactic factor, GCP1, interleukin 8, C-X-C motif chemokine 8, MDNCF, T cell chemotactic factor, beta-thromboglobulin-like protein, NAP1, NAF, alveolar macrophage chemotactic factor I, IL8, emoctakin, granulocyte chemotactic protein 1, MONAP
Source: HGNC:6025
Biotype: protein coding gene
Nos1
(Mus musculus)Gene
Name: nitric oxide synthase 1, neuronal
Synonyms: NO, nitric oxide synthase 1 (macrophage), nNOS, RIKEN cDNA 2310005C01 gene, Nos-1, 2310005C01Rik, bNOS
Source: MGI:97360
Biotype: protein coding gene
Camk2a
(Mus musculus)Gene
Name: calcium/calmodulin-dependent protein kinase II alpha
Synonyms: PK2CDD, expressed sequence R74975, mKIAA0968, PKCCD, R74975, alpha-CaMKII
Source: MGI:88256
Biotype: protein coding gene
Rock1
(Mus musculus)Gene
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: P160Rock, RIKEN cDNA 1110055K06 gene, 1110055K06Rik, ROCK-I, Rock-I
Source: MGI:107927
Biotype: protein coding gene
Plcb1
(Mus musculus)Gene
Name: phospholipase C, beta 1
Synonyms: RATPHOSPHB, 3110043I21Rik, AI132408, RIKEN cDNA 3110043I21 gene, Phosphb, expressed sequence AI132408, PLCbeta1, PLC'1, mKIAA0581
Source: MGI:97613
Biotype: protein coding gene
foxo
(Drosophila melanogaster)Gene
Name: forkhead box, sub-group O
Synonyms: Foxo, forkhead boxO transcription factor, forkhead box sub-group O, dFoxO, dFOXO, fd88A, 3143, DfoxO, TORC, forkhead box-containing protein, O subfamily, FOXO1, fOXO, foxO, Afx, Forkhead Box O, CG3143, dfoxo, Forkhead box type O, DFOXO, Q95V55, Foxo1, Akh, Forkhead box, FoxO, FOXO, dFoxo, Dfoxo, Forkhead box O, FKHR, cg3143, dfoxO, anon-WO0118547.374, forkhead box, subgroup O, DmQ95V5, Forkhead bOX-containing protein, subfamily O, forkhead transcription factor
Source: FB:FBgn0038197
Biotype: protein coding gene
Rgs7
(Mus musculus)Gene
Name: regulator of G protein signaling 7
Synonyms: Not Available
Source: MGI:1346089
Biotype: protein coding gene
Zdhhc3
(Mus musculus)Gene
Name: zinc finger, DHHC domain containing 3
Synonyms: RIKEN cDNA 2210017C02 gene, RIKEN cDNA 1110020O22 gene, 1110020O22Rik, 1810006O10Rik, RIKEN cDNA 1810006O10 gene, 2210017C02Rik, Zfp373, GODZ
Source: MGI:1926134
Biotype: protein coding gene
Dnm2
(Mus musculus)Gene
Name: dynamin 2
Synonyms: DYIIAAB, Mutant line 2159, b2b2159Clo, Dyn2
Source: MGI:109547
Biotype: protein coding gene
ITGB3
(Homo sapiens)Gene
Name: integrin subunit beta 3
Synonyms: integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), integrin beta-3, CD61, GT2, integrin beta chain, beta 3, GT, integrin beta 3, GPIIIa, BDPLT16, platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa, GP3A, BDPLT24, antigen CD61, BDPLT2
Source: HGNC:6156
Biotype: protein coding gene
Hif1a
(Mus musculus)Gene
Name: hypoxia inducible factor 1, alpha subunit
Synonyms: HIF1alpha, bHLHe78, MOP1, HIF-1alpha, expressed sequence AA959795, AA959795, HIF1-alpha
Source: MGI:106918
Biotype: protein coding gene
Drd3
(Rattus norvegicus)Gene
Name: dopamine receptor D3
Synonyms: D3 receptor, dopaminergic receptor D3, D(3) dopamine receptor, dopamine D3 receptor isoform, dopamine D3 receptor
Source: RGD:2521
Biotype: protein coding gene
Arrb1
(Mus musculus)Gene
Name: arrestin, beta 1
Synonyms: AW208571, expressed sequence AW208571, 1200006I17Rik, RIKEN cDNA G430100A01 gene, RIKEN cDNA 1200006I17 gene, BARRES, beta-arrestin1, G430100A01Rik
Source: MGI:99473
Biotype: protein coding gene
PDE3A
(Homo sapiens)Gene
Name: phosphodiesterase 3A
Synonyms: cGMP-inhibited cAMP phosphodiesterase, HTNB, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, cyclic GMP inhibited phosphodiesterase A, phosphodiesterase 3A, cGMP-inhibited, cAMP phosphodiesterase, myocardial cGMP-inhibited, cGMP-inhibited 3',5'-cyclic phosphodiesterase A, FLJ37884, CGI-PDE-A, CGI-PDE, cyclic GMP-inhibited phosphodiesterase A, CGI-PDE A
Source: HGNC:8778
Biotype: protein coding gene
Grk2
(Mus musculus)Gene
Name: G protein-coupled receptor kinase 2
Synonyms: Bark-1, Adrbk-1, beta-adrenergic receptor kinase 1, beta-AR kinase-1, beta ARK1, adrenergic receptor kinase, beta 1, beta-adrenergic receptor kinase-1, betaARK1, Adrbk1, BARK1, beta ARK, GRK-2
Source: MGI:87940
Biotype: protein coding gene
GIPR
(Homo sapiens)Gene
Name: gastric inhibitory polypeptide receptor
Synonyms: PGQTL2, gastric inhibitory peptide receptor, GIP-R, MGC126722, glucose-dependent insulinotropic polypeptide receptor
Source: HGNC:4271
Biotype: protein coding gene
ALK
(Homo sapiens)Gene
Name: ALK receptor tyrosine kinase
Synonyms: anaplastic lymphoma kinase (ki-1), NBLST3, ALK tyrosine kinase receptor, anaplastic lymphoma kinase, mutant anaplastic lymphoma kinase, CD246 antigen, TFG/ALK, CD246, anaplastic lymphoma receptor tyrosine kinase, ALK1
Source: HGNC:427
Biotype: protein coding gene
DRD2
(Homo sapiens)Gene
Name: dopamine receptor D2
Synonyms: D2DR, dopamine D2 receptor, D2R, dopamine receptor D2 isoform, D(2) dopamine receptor, dopamine receptor 2, seven transmembrane helix receptor
Source: HGNC:3023
Biotype: protein coding gene
GRM5
(Homo sapiens)Gene
Name: glutamate metabotropic receptor 5
Synonyms: mGlu5, glutamate receptor, metabotropic 5, metabotropic glutamate receptor 5 variant H, metabotropic glutamate receptor 5, metabotropic glutamate receptor 5 variant G, MGLUR5, GRM5 variant 9, PPP1R86, metabotropic glutamate receptor 5 variant F, GPRC1E
Source: HGNC:4597
Biotype: protein coding gene
MET
(Homo sapiens)Gene
Name: MET proto-oncogene, receptor tyrosine kinase
Synonyms: HGF receptor, HGF/SF receptor, DA11, proto-oncogene c-Met, OSFD, HGFR, mesenchymal-epithelial transition factor, scatter factor receptor, tyrosine-protein kinase Met, hepatocyte growth factor receptor, met proto-oncogene tyrosine kinase, cMet, RCCP2, soluble MET variant 12, PTPRZ1/MET fusion, c-Met, oncogene MET, DFNB97, AUTS9, SF receptor
Source: HGNC:7029
Biotype: protein coding gene
Adrb2
(Mus musculus)Gene
Name: adrenergic receptor, beta 2
Synonyms: beta 2-AR, Gpcr7, B-adrenergic binding, beta 2-adrenoceptor, Badm, Adrb-2, G protein coupled receptor 7
Source: MGI:87938
Biotype: protein coding gene
PHB1
(Homo sapiens)Gene
Name: prohibitin 1
Synonyms: BAP32, HEL-S-54e, epididymis luminal protein 215, PHB, HEL-215, epididymis secretory sperm binding protein Li 54e, prohibitin
Source: HGNC:8912
Biotype: protein coding gene
Trem2
(Mus musculus)Gene
Name: triggering receptor expressed on myeloid cells 2
Synonyms: Trem2-Mia, Trem2-Mib, triggering receptor expressed on myeloid cells 2c, triggering receptor expressed on myeloid cells 2b, triggering receptor expressed on myeloid cells 2a, Trem2a, Trem2c, Trem2b
Source: MGI:1913150
Biotype: protein coding gene
Aplnr
(Mus musculus)Gene
Name: apelin receptor
Synonyms: Agtrl1, msr/apj, angiotensin receptor-like 1, Apj, APJ
Source: MGI:1346086
Biotype: protein coding gene
RACK1
(Homo sapiens)Gene
Name: receptor for activated C kinase 1
Synonyms: protein homologous to chicken B complex protein, guanine nucleotide binding, H12.3, lung cancer oncogene 7, PIG21, receptor of activated protein C kinase 1, proliferation-inducing gene 21, guanine nucleotide binding protein beta polypeptide 2-like 1, Gnb2-rs1, guanine nucleotide-binding protein subunit beta-like protein 12.3, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, GNB2L1, HLC-7, small ribosomal subunit protein RACK1, receptor of activated protein kinase C 1, cell proliferation-inducing gene 21 protein, human lung cancer oncogene 7 protein, guanine nucleotide-binding protein subunit beta-2-like 1
Source: HGNC:4399
Biotype: protein coding gene