Version: 8.0.0Date: Tue Jan 28 2025
Gene Diseases: orofacial cleft
Msx1
(Mus musculus)Gene
Name: msh homeobox 1
Synonyms: Hox-7, msh, AA675338, expressed sequence AI324650, homeo box-7 cluster, msh-like, Hox7, AI324650, expressed sequence AA675338, muscle-segment homeobox, Hox7.1
Source: MGI:97168
Biotype: protein coding gene
Bmp4
(Mus musculus)Gene
Name: bone morphogenetic protein 4
Synonyms: Bmp2b, bone morphogenetic protein 2b, BOMPR4A, Bmp2b-1, Bmp-4, bone morphogenetic protein 2b 1, Bmp2b1
Source: MGI:88180
Biotype: protein coding gene
dpp
(Drosophila melanogaster)Gene
Name: decapentaplegic
Synonyms: shv, DPP, Dpp, ho, TGF-b, blink, M(2)23AB, DmDPP, l(2)10638, M(2)LS1, Decapentaplegic/Bone Morphogenetic Protein, Haplo-insufficient, TGF-beta, Tg, CG9885, DPP-C, TGFbeta, blk, Tegula, Hin-d, Bmp, BMP, Decapentaplegic, bone morphogenetic protein, l(2)22Fa, Tgfbeta, heldout, Dpp/TGFbeta, bone morphogenic protein, shortvein, l(2)k17036, Dm-DPP
Source: FB:FBgn0000490
Biotype: protein coding gene
MTHFR
(Homo sapiens)Gene
Name: methylenetetrahydrofolate reductase
Synonyms: methylenetetrahydrofolate reductase (NAD(P)H), methylenetetrahydrofolate reductase (NADPH), 5,10-methylenetetrahydrofolate reductase (NADPH)
Source: HGNC:7436
Biotype: protein coding gene
BMP4
(Homo sapiens)Gene
Name: bone morphogenetic protein 4
Synonyms: MCOPS6, bone morphogenetic protein 2B, bone morphogenetic protein 4 preproprotein, BMP2B, OFC11, BMP-2B, BMP-4, ZYME, BMP2B1
Source: HGNC:1071
Biotype: protein coding gene
CDH1
(Homo sapiens)Gene
Name: cadherin 1
Synonyms: BCDS1, LCAM, calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, ECAD, CDHE, cadherin 1, E-cadherin (epithelial), CAM 120/80, UVO, uvomorulin, cadherin 1, type 1, E-cadherin (epithelial), E-cadherin 1, cadherin 1, type 1, E-Cadherin, CD324, cadherin-1, epithelial cadherin, Arc-1, truncated cadherin 1 type 1
Source: HGNC:1748
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, dmp53, D-p53, Dmp53, Dm-P53, DmP53, dmP53, protein 53, CG31325, p53-like regulator of apoptosis and cell cycle, Drosophila p53
Source: FB:FBgn0039044
Biotype: protein coding gene
CDC42
(Homo sapiens)Gene
Name: cell division cycle 42
Synonyms: G25K, GTP-binding protein, 25kD, GTP binding protein, 25kDa, small GTP binding protein CDC42, G25K GTP-binding protein, cell division cycle 42 (GTP binding protein, 25kDa), CDC42Hs, dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)), growth-regulating protein, dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)), TKS, cell division control protein 42 homolog
Source: HGNC:1736
Biotype: protein coding gene
dbl-1
(Caenorhabditis elegans)Gene
Name: DPP/BMP-Like 1
Synonyms: cet-1, CELE_T25F10.2, T25F10.2
Source: WB:WBGene00000936
Biotype: protein coding gene
Cdh1
(Mus musculus)Gene
Name: cadherin 1
Synonyms: Ecad, uvomorulin, expressed sequence AA960649, UM, Um, L-CAM, E-cad, AA960649, E-cadherin
Source: MGI:88354
Biotype: protein coding gene
FGFR1
(Homo sapiens)Gene
Name: fibroblast growth factor receptor 1
Synonyms: FLG, basic fibroblast growth factor receptor 1, FLT2, Kallmann syndrome 2 (autosomal dominant), fms-related tyrosine kinase 2, HBGFR, HRTFDS, FLT-2, FGFR-1, BFGFR, FGFBR, bFGF-R-1, heparin-binding growth factor receptor, FMS-like tyrosine kinase 2, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), proto-oncogene c-Fgr, CD331, KAL2, N-SAM, soluble FGFR1 variant 2, soluble FGFR1 variant 1, FLJ99988, ECCL, CEK, FGFR1/PLAG1 fusion, OGD, hydroxyaryl-protein kinase, HH2
Source: HGNC:3688
Biotype: protein coding gene
Tgfbr2
(Mus musculus)Gene
Name: transforming growth factor, beta receptor II
Synonyms: TbetaRII, TGF-beta 2, expressed sequence AU042018, TbetaR-II, 1110020H15Rik, RIKEN cDNA 1110020H15 gene, TBR-II, AU042018, Tgfbr2T
Source: MGI:98729
Biotype: protein coding gene
Irf6
(Mus musculus)Gene
Name: interferon regulatory factor 6
Synonyms: E230028I05Rik, expressed sequence AI876454, AI876454, RIKEN cDNA E230028I05 gene
Source: MGI:1859211
Biotype: protein coding gene
cher
(Drosophila melanogaster)Gene
Name: cheerio
Synonyms: FLN90, Filamin isoform B, filamin B, Filamin-A, Filamin-B, Fil, FLN, dFil, Cheerio, filamin, Cher, Filamin-1, joy, sko, shi kong, Cherrio, Filamin, CG3937, filamin-240
Source: FB:FBgn0014141
Biotype: protein coding gene
TGFBR2
(Homo sapiens)Gene
Name: transforming growth factor beta receptor 2
Synonyms: transforming growth factor, beta receptor II gamma, transforming growth factor beta receptor II, TGF-beta receptor type-2, LDS1B, TGFR-2, transforming growth factor beta receptor type IIC, TGFbeta-RII, TGF-beta receptor type II, LDS2, TGF-beta type II receptor, transforming growth factor, beta receptor ii, transforming growth factor, beta receptor II (70/80kDa) isoform 2, TAAD2, transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II epsilon, AAT3, transforming growth factor, beta receptor II beta, LDS2B, tbetaR-II, transforming growth factor beta receptor 2 transcript variant SE, FAA3, TGF-beta receptor type IIB, transforming growth factor-beta receptor type II, TBR-ii, RIIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II alpha, TBRII, transforming growth factor, beta receptor II delta, MFS2
Source: HGNC:11773
Biotype: protein coding gene
Dll
(Drosophila melanogaster)Gene
Name: Distal-less
Synonyms: Art, l(2)01092, Distall-less, Distallless, dll, distal-less, DLL, l(2)387, Distal-less, distalless, BcDNA:LP01770, Brista, Distalless, Enhancer of Arp, CG3629, 2.7, En(Arp), E(Arp), Ba
Source: FB:FBgn0000157
Biotype: protein coding gene
nmy-1
(Caenorhabditis elegans)Gene
Name: Non-muscle MYosin 1
Synonyms: F52B10.1, CELE_F52B10.1
Source: WB:WBGene00003776
Biotype: protein coding gene
NOG
(Homo sapiens)Gene
Name: noggin
Synonyms: symphalangism 1 (proximal), SYNS1A, SYM1, SYNS1
Source: HGNC:7866
Biotype: protein coding gene
fln-1
(Caenorhabditis elegans)Gene
Name: FiLamiN (actin binding protein) homolog 1
Synonyms: CELE_Y66H1B.2, Y66H1B.2
Source: WB:WBGene00022048
Biotype: protein coding gene
Dr
(Drosophila melanogaster)Gene
Name: Drop
Synonyms: 99B, muscle specific homeobox, msh, Msh, muscle segment homeobox, Dr/msh, Dr/Msh, lottchen, Muscle segment homeobox, muscle-specific homeodomain 1, l(3)FA30, ltt, muscle-specific homeodomain, Drop, Msx, msh-1, 153515_at, msh1, Muscle specific homeobox, CG1897, Dr-distal
Source: FB:FBgn0000492
Biotype: protein coding gene
bmp4
(Danio rerio)Gene
Name: bone morphogenetic protein 4
Synonyms: zgc:100779, bmp-4, zbmp-4, etID309887.17
Source: ZFIN:ZDB-GENE-980528-2059
Biotype: protein coding gene
MTHFD1
(Homo sapiens)Gene
Name: methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
Synonyms: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase, c1-tetrahydrofolate synthase, MTHFC, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase, MTHFD, C-1-tetrahydrofolate synthase, cytoplasmic, CIMAH, C1-THF synthase, cytoplasmic C-1-tetrahydrofolate synthase
Source: HGNC:7432
Biotype: protein coding gene
smo-1
(Caenorhabditis elegans)Gene
Name: SUMO (ubiquitin-related) homolog 1
Synonyms: K12C11.2, CELE_K12C11.2, K12C11.f, SMT3
Source: WB:WBGene00004888
Biotype: protein coding gene
so
(Drosophila melanogaster)Gene
Name: sine oculis
Synonyms: old, somda, soD, sine oculus, medusa, mda, Sine Oculis, Droplet, sinus oculis, med, optic lobe defective, Sine oculis, absent minded, So, SO, ami, sine oculis, CG11121, Drl
Source: FB:FBgn0003460
Biotype: protein coding gene
SUMO1
(Homo sapiens)Gene
Name: small ubiquitin like modifier 1
Synonyms: ubiquitin-homology domain protein PIC1, DAP1, SMT3H3, PIC1, smt3 suppressor of mif two 3 homolog 1 (yeast), GMP1, small ubiquitin-like modifier 1, GAP modifying protein 1, ubiquitin-like protein UBL1, DAP-1, SENP2, OFC10, small ubiquitin-related modifier 1, sentrin, UBL1, SMT3 homolog 3, ubiquitin-like protein SMT3C, SUMO-1, SMT3 suppressor of mif two 3 homolog 1, SMT3C, SMT3
Source: HGNC:12502
Biotype: protein coding gene
MYH9
(Homo sapiens)Gene
Name: myosin heavy chain 9
Synonyms: myosin-9, NMHC-II-A, NMMHC II-a, BDPLT6, NMMHCA, non-muscle myosin heavy polypeptide 9, MHA, nonmuscle myosin heavy chain II-A, MGC104539, NMMHC-IIA, myosin, heavy polypeptide 9, cellular myosin heavy chain, type A, MATINS, non-muscle myosin heavy chain IIa, MYH9 variant protein, FTNS, DFNA17, myosin heavy chain, non-muscle IIa, non-muscle myosin heavy chain A, EPSTS, myosin, heavy chain 9, non-muscle, NMMHC-A, non-muscle myosin heavy chain 9, nonmuscle myosin IIA2
Source: HGNC:7579
Biotype: protein coding gene
Col2a1
(Mus musculus)Gene
Name: collagen, type II, alpha 1
Synonyms: Dmm, Col2a-1, Lpk, Del1, M100413, Col2a, RIKEN Genomic Sciences Center (GSC), 856, M100856, Rgsc856, RIKEN Genomic Sciences Center (GSC), 413, Col2, Rgsc413, CG2A1A, disproportionate micromelia, longpockets, COLLII, procollagen, type II
Source: MGI:88452
Biotype: protein coding gene
Col2a1
(Rattus norvegicus)Gene
Name: collagen type II alpha 1 chain
Synonyms: Procollagen II alpha 1, collagen, type II, alpha 1, procollagen, type II, alpha 1, collagen alpha-1(II) chain, CG2A1A, alpha-1 type II collagen, collagen type II (Col2A1) gene, enhancer region, COLLII
Source: RGD:2375
Biotype: protein coding gene
ADE3
(Saccharomyces cerevisiae)Gene
Name: ADEnine requiring
Synonyms: YGR204W
Source: SGD:S000003436
Biotype: protein coding gene
AXIN2
(Homo sapiens)Gene
Name: axin 2
Synonyms: MGC126582, conductin, axin-2, axis inhibition protein 2, AXIL, axin-like protein, ODCRCS, MGC10366, DKFZp781B0869
Source: HGNC:904
Biotype: protein coding gene
Axin2
(Mus musculus)Gene
Name: axin 2
Synonyms: axin-2, Conductin, Axil, axil
Source: MGI:1270862
Biotype: protein coding gene
tbx-37
(Caenorhabditis elegans)Gene
Name: T BoX family 37
Synonyms: CELE_Y47D3A.12, Y47D3A.12
Source: WB:WBGene00006556
Biotype: protein coding gene
nmy-2
(Caenorhabditis elegans)Gene
Name: Non-muscle MYosin 2
Synonyms: F20G4.3, CELE_F20G4.3
Source: WB:WBGene00003777
Biotype: protein coding gene
UFD1
(Saccharomyces cerevisiae)Gene
Name: Ubiquitin Fusion Degradation protein
Synonyms: YGR048W
Source: SGD:S000003280
Biotype: protein coding gene
SMT3
(Saccharomyces cerevisiae)Gene
Name: Suppressor of Mif Two
Synonyms: YDR510W
Source: SGD:S000002918
Biotype: protein coding gene
Trp63
(Mus musculus)Gene
Name: transformation related protein 63
Synonyms: expressed sequence AI462811, p53-related protein 1, P73l, KET protein, Tp73l, Trp53rp1, p63, AI462811, p73L, deltaNp63, Ket, TAp63, p51/p63
Source: MGI:1330810
Biotype: protein coding gene
Satb2
(Mus musculus)Gene
Name: special AT-rich sequence binding protein 2
Synonyms: mKIAA1034, RGD1562369, BAP002, bone alkaline phospatase mutant 002
Source: MGI:2679336
Biotype: protein coding gene
Myh9
(Mus musculus)Gene
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: myosin IIA, Fltn, E030044M24Rik, Myhn-1, Myhn1, myosin heavy chain, nonmuscular, type A, NMIIA, D0Jmb2, flectin, expressed sequence C80049, NMHC II-A, DNA segment, Jeremy M. Boss 2, RIKEN cDNA E030044M24 gene, C80049, Myh9l1
Source: MGI:107717
Biotype: protein coding gene
ACS2
(Saccharomyces cerevisiae)Gene
Name: Acetyl CoA Synthetase
Synonyms: YLR153C
Source: SGD:S000004143
Biotype: protein coding gene
fgfr1a
(Danio rerio)Gene
Name: fibroblast growth factor receptor 1a
Synonyms: cb231, sb:cb231, fgfr1
Source: ZFIN:ZDB-GENE-980526-255
Biotype: protein coding gene
Cdh1
(Rattus norvegicus)Gene
Name: cadherin 1
Synonyms: uvomorulin, cadherin-1, E-cadherin, epithelial cadherin
Source: RGD:69279
Biotype: protein coding gene
MSX1
(Homo sapiens)Gene
Name: msh homeobox 1
Synonyms: msh homeo box 1, homeobox protein Hox-7, HOX7, STHAG1, homeobox 7, homeo box, msh-like 1, ECTD3, msh homeobox 1-like protein, HYD1, homeobox protein MSX-1, msh homeobox homolog 1
Source: HGNC:7391
Biotype: protein coding gene
TP63
(Homo sapiens)Gene
Name: tumor protein p63
Synonyms: chronic ulcerative stomatitis protein, OFC8, amplified in squamous cell carcinoma, keratinocyte transcription factor KET, p51, B(p51A), p73H, CUSP, TP53CP, EEC3, RHS, NBP, tumor protein p53-competing protein, tumor protein p53-like, tumor protein p63 deltaN isoform delta, AIS, SHFM4, transformation-related protein 63, p63, p40, B(p51B), TP73L, p73L, LMS, TP53L, p53CP, KET, tumor protein p73-like, tumor protein 63
Source: HGNC:15979
Biotype: protein coding gene
egl-15
(Caenorhabditis elegans)Gene
Name: EGg Laying defective 15
Synonyms: CELE_F58A3.2, F58A3.2
Source: WB:WBGene00001184
Biotype: protein coding gene
Gstt1
(Rattus norvegicus)Gene
Name: glutathione S-transferase theta 1
Synonyms: GST class-theta-1, glutathione S-transferase, theta 1, GSTYRS, glutathione S-transferase theta-1, Glutathione S-transferase 1 (theta), glutathione S-transferase 5, GST 5-5
Source: RGD:2765
Biotype: protein coding gene
COL2A1
(Homo sapiens)Gene
Name: collagen type II alpha 1 chain
Synonyms: STL1, collagen type II alpha 1, COL11A3, alpha-1 type II collagen, cartilage collagen, chondrocalcin, arthroophthalmopathy, progressive (Stickler syndrome), ANFH, collagen, type II, alpha 1, collagen alpha-1(II) chain, SEDC, MGC131516, collagen II, alpha-1 polypeptide, AOM
Source: HGNC:2200
Biotype: protein coding gene
PRMT1
(Homo sapiens)Gene
Name: protein arginine methyltransferase 1
Synonyms: interferon receptor 1-bound protein 4, IR1B4, highly conserved protein 1, HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2, HRMT1L2, HMT1 hnRNP methyltransferase-like 2, histone-arginine N-methyltransferase PRMT1, heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2, HCP1, protein arginine N-methyltransferase 1, heterogeneous nuclear ribonucleoproteins methyltransferase-like 2 (s. cerevisiae), ANM1
Source: HGNC:5187
Biotype: protein coding gene
cdc-42
(Caenorhabditis elegans)Gene
Name: Cell Division Cycle related 42
Synonyms: CDC42Ce, CELE_R07G3.1, R07G3.1
Source: WB:WBGene00000390
Biotype: protein coding gene
Meis2
(Mus musculus)Gene
Name: Meis homeobox 2
Synonyms: stimulated by retinoic acid gene 10, Stra10, RIKEN cDNA A430109D20 gene, myeloid ecotropic viral integration site-related gene 1, A430109D20Rik, Mrg1
Source: MGI:108564
Biotype: protein coding gene
Tgfbr2
(Rattus norvegicus)Gene
Name: transforming growth factor, beta receptor 2
Synonyms: TGF-beta 2, transforming growth factor beta, receptor 2, TGF-beta receptor type-2, TGFR-2, tbetaR-II, transforming growth factor, beta receptor IIT, transforming growth factor beta receptor 2, TGF-beta receptor type II, transforming growth factor-beta type II receptor, transforming growth factor-b type II receptor, TGF-beta type II receptor, transforming growth factor-beta receptor type II, transforming growth factor, beta receptor II, transforming growth factor beta receptor type II, Tgfbr2T
Source: RGD:69651
Biotype: protein coding gene