Version: 8.1.0Date: Fri Apr 18 2025
Gene Molecular Function: ubiquitin protein ligase activity
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, RING finger protein 53, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, breast cancer 1, early onset, Fanconi anemia, complementation group S, IRIS, breast cancer type 1 susceptibility protein, BRCAI, PNCA4, PSCP, protein phosphatase 1, regulatory subunit 53, BROVCA1, truncated BRCA1, breast cancer 1, FANCS, PPP1R53
Source: HGNC:1100
Biotype: protein coding gene
MARCHF6
(Homo sapiens)Gene
Name: membrane associated ring-CH-type finger 6
Synonyms: membrane associated ring finger 6, TEB4, membrane-associated RING-CH protein VI, E3 ubiquitin-protein ligase MARCHF6, RING-type E3 ubiquitin transferase MARCH6, MARCH6, membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase, membrane-associated RING finger protein 6, MARCH-VI, RING-type E3 ubiquitin transferase MARCHF6, KIAA0597, FCMTE3, DOA10, E3 ubiquitin-protein ligase MARCH6, membrane-associated RING-CH finger protein 6, RING finger protein 176, protein TEB-4, FAME3, doa10 homolog, RNF176
Source: HGNC:30550
Biotype: protein coding gene
Prkn
(Mus musculus)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: PRKN, Parkinson disease (autosomal recessive, juvenile) 2, parkin, Park2, Parkin, Park
Source: MGI:1355296
Biotype: protein coding gene
park
(Drosophila melanogaster)Gene
Name: parkin
Synonyms: CG10523, Prkn, parkin, dparkin, D-parkin, SD01679, dParkin, Parkin F, PARK2, PARK, Park, prkn, PARKIN, AAN12155.1, pk, PK, dpark, ortholog of PRKN, Dpark, dpk, dPARKIN, park, park1, Parkin
Source: FB:FBgn0041100
Biotype: protein coding gene
MDM2
(Homo sapiens)Gene
Name: MDM2 proto-oncogene
Synonyms: oncoprotein Mdm2, HDMX, MDM2 proto-oncogene, E3 ubiquitin protein ligase, MGC71221, Mdm2, p53 E3 ubiquitin protein ligase homolog, ACTFS, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein, HDM2 transcript variant MYO-18, MGC5370, hdm2, HDM2 transcript variant MYO-32, HDM2 transcript variant MYO-24, HDM2 transcript variant MYO-4, HDM2 transcript variant MYO-25, ubiquitin-protein ligase E3 Mdm2, MDM2 oncogene, E3 ubiquitin protein ligase, MDM2 variant FB28, double minute 2, human homolog of, p53-binding protein, HDM2 transcript variant MYO-1, HDM2 transcript variant MYO-26, Mdm2 p53 binding protein homolog, HDM2 transcript variant MYO-20, MDM2 variant FB30, E3 ubiquitin-protein ligase Mdm2, double minute 2, human homolog of, LSKB
Source: HGNC:6973
Biotype: protein coding gene
RSP5
(Saccharomyces cerevisiae)Gene
Name: Reverses Spt- Phenotype
Synonyms: UBY1, MUT2, HPG1, SMM1, YER125W, MDP1, NPI1
Source: SGD:S000000927
Biotype: protein coding gene
Traf6
(Mus musculus)Gene
Name: TNF receptor-associated factor 6
Synonyms: C630032O20Rik, RIKEN cDNA 2310003F17 gene, AI851288, RIKEN cDNA C630032O20 gene, expressed sequence AI851288, 2310003F17Rik
Source: MGI:108072
Biotype: protein coding gene
FBXO6
(Homo sapiens)Gene
Name: F-box protein 6
Synonyms: Fbx6b, F-box protein that recognizes sugar chains 2, FBG2, F-box/G-domain protein 2, F-box protein FBG2, FBX6, F-box protein Fbx6, FBS2, F-box only protein 6
Source: HGNC:13585
Biotype: protein coding gene
Trim30a
(Mus musculus)Gene
Name: tripartite motif-containing 30A
Synonyms: Trim30, Rpt-1, tripartite motif-containing 30, regulatory protein, T lymphocyte 1, RGD1566132, Rpt1
Source: MGI:98178
Biotype: protein coding gene
CDC42
(Homo sapiens)Gene
Name: cell division cycle 42
Synonyms: G25K, GTP-binding protein, 25kD, small GTP binding protein CDC42, GTP binding protein, 25kDa, G25K GTP-binding protein, cell division cycle 42 (GTP binding protein, 25kDa), dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)), CDC42Hs, growth-regulating protein, dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)), TKS, cell division control protein 42 homolog
Source: HGNC:1736
Biotype: protein coding gene
RNF167
(Homo sapiens)Gene
Name: ring finger protein 167
Synonyms: RING-type E3 ubiquitin transferase RNF167, E3 ubiquitin-protein ligase RNF167, 5730408C10Rik, DKFZp566H073, RING105, LP2254
Source: HGNC:24544
Biotype: protein coding gene
SHPRH
(Homo sapiens)Gene
Name: SNF2 histone linker PHD RING helicase
Synonyms: FLJ27258, MGC134886, FLJ45012, RAD5, KIAA2023, E3 ubiquitin-protein ligase SHPRH, 2610103K11Rik, FLJ37625, SNF2, histone-linker, PHD and RING finger domain-containing helicase, FLJ90837, bA545I5.2, RING-type E3 ubiquitin transferase SHPRH, SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
Source: HGNC:19336
Biotype: protein coding gene
CUL3
(Homo sapiens)Gene
Name: cullin 3
Synonyms: cullin-3, NEDAUS, PHA2E, FLJ25665, CUL-3
Source: HGNC:2553
Biotype: protein coding gene
PRKN
(Homo sapiens)Gene
Name: parkin RBR E3 ubiquitin protein ligase
Synonyms: Parkinson disease (autosomal recessive, juvenile) 2, parkin, PDJ, parkinson disease protein 2, LPRS2, parkinson protein 2, E3 ubiquitin protein ligase (parkin), E3 ubiquitin ligase, AR-JP, parkin 2, parkinson juvenile disease protein 2, PARK2, E3 ubiquitin-protein ligase parkin, parkinson protein 2 E3 ubiquitin protein ligase
Source: HGNC:8607
Biotype: protein coding gene
Rpgr
(Mus musculus)Gene
Name: retinitis pigmentosa GTPase regulator
Synonyms: Rp3h, Rd9, retinal degeneration 9, retinitis pigmentosa 3 homolog
Source: MGI:1344037
Biotype: protein coding gene
RNF10
(Homo sapiens)Gene
Name: ring finger protein 10
Synonyms: RIE2, KIAA0262, MGC126764, E3 ubiquitin-protein ligase RNF10, MGC126758
Source: HGNC:10055
Biotype: protein coding gene
APC1
(Saccharomyces cerevisiae)Gene
Name: Anaphase Promoting Complex subunit
Synonyms: YNL172W
Source: SGD:S000005116
Biotype: protein coding gene
Med1
(Mus musculus)Gene
Name: mediator complex subunit 1
Synonyms: CRSP210, peroxisome proliferator activated receptor binding protein, TRAP220, RGD1559552, Pparbp, l11Jus15, DRIP205, expressed sequence AI480703, AI480703, TRAP 220, PBP
Source: MGI:1100846
Biotype: protein coding gene
Ube3a
(Mus musculus)Gene
Name: ubiquitin protein ligase E3A
Synonyms: 5830462N02Rik, A130086L21Rik, RIKEN cDNA A130086L21 gene, Hpve6a, RIKEN cDNA 5830462N02 gene, E6-AP ubiquitin protein ligase
Source: MGI:105098
Biotype: protein coding gene
PEX10
(Homo sapiens)Gene
Name: peroxisomal biogenesis factor 10
Synonyms: peroxisome biogenesis factor 10, RNF69, PBD6B, RING finger protein 69, PBD6A, peroxin-10, peroxisome assembly protein 10, peroxin 10, NALD, MGC1998
Source: HGNC:8851
Biotype: protein coding gene
RNF8
(Homo sapiens)Gene
Name: ring finger protein 8
Synonyms: ring finger protein (C3HC4 type) 8, FLJ12013, KIAA0646, UBC13/UEV-interacting ring finger protein, hRNF8, ring finger protein 8, E3 ubiquitin protein ligase, E3 ubiquitin-protein ligase RNF8, RING-type E3 ubiquitin transferase RNF8, C3HC4-type zinc finger protein
Source: HGNC:10071
Biotype: protein coding gene
RAD18
(Homo sapiens)Gene
Name: RAD18 E3 ubiquitin protein ligase
Synonyms: hHR18, RAD18 homolog, RAD18, E3 ubiquitin protein ligase, RING-type E3 ubiquitin transferase RAD18, postreplication repair protein RAD18, E3 ubiquitin-protein ligase RAD18, RAD18, S. cerevisiae, homolog, RING finger protein 73, hRAD18, RNF73, postreplication repair protein hRAD18p
Source: HGNC:18278
Biotype: protein coding gene
ZNF598
(Homo sapiens)Gene
Name: zinc finger protein 598, E3 ubiquitin ligase
Synonyms: zinc finger protein 598, HEL2, E3 ubiquitin-protein ligase ZNF598, FLJ00086, DKFZp762F135
Source: HGNC:28079
Biotype: protein coding gene
Rag1
(Mus musculus)Gene
Name: recombination activating 1
Synonyms: Rag-1, recombination activating gene 1
Source: MGI:97848
Biotype: protein coding gene
RKR1
(Saccharomyces cerevisiae)Gene
Name: RING domain mutant Killed by Rtf1 deletion
Synonyms: YMR247C, LTN1
Source: SGD:S000004861
Biotype: protein coding gene
EIF2AK4
(Homo sapiens)Gene
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: KIAA1338, GCN2, eukaryotic translation initiation factor 2-alpha kinase 4, PVOD2, general control nonderepressible 2, GCN2 eIF2alpha kinase, eIF-2-alpha kinase GCN2, GCN2-like protein
Source: HGNC:19687
Biotype: protein coding gene
MKRN1
(Homo sapiens)Gene
Name: makorin ring finger protein 1
Synonyms: RING finger protein 61, E3 ubiquitin-protein ligase makorin-1, FLJ21334, RNF61, RING-type E3 ubiquitin transferase makorin-1
Source: HGNC:7112
Biotype: protein coding gene
CG5347
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0030578
Biotype: protein coding gene
TOM1
(Saccharomyces cerevisiae)Gene
Name: Temperature dependent Organization in Mitotic nucleus or Trigger Of Mitosis
Synonyms: YDR457W
Source: SGD:S000002865
Biotype: protein coding gene
LTN1
(Homo sapiens)Gene
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: FLJ11053, E3 ubiquitin-protein ligase listerin, RING finger protein 160, ZNF294, C21orf10, C21orf98, RNF160, RING-type E3 ubiquitin transferase listerin, zinc finger protein 294, KIAA0714
Source: HGNC:13082
Biotype: protein coding gene
RPGR
(Homo sapiens)Gene
Name: retinitis pigmentosa GTPase regulator
Synonyms: retinitis pigmentosa 3 GTPase regulator, PCDX, CORDX1, RP3, RP15, CRD, COD1, orf15, XLRP3, X-linked retinitis pigmentosa GTPase regulator, retinitis pigmentosa 15
Source: HGNC:10295
Biotype: protein coding gene
Cul3
(Mus musculus)Gene
Name: cullin 3
Synonyms: AW146203, expressed sequence AI467304, AI467304, expressed sequence AW146203
Source: MGI:1347360
Biotype: protein coding gene
Cop1
(Mus musculus)Gene
Name: COP1, E3 ubiquitin ligase
Synonyms: Rfwd2, ring finger and WD repeat domain 2, expressed sequence C80879, RGD1304773, expressed sequence AI316802, AI316802, C80879
Source: MGI:1347046
Biotype: protein coding gene
SAN1
(Saccharomyces cerevisiae)Gene
Name: Sir Antagonist
Synonyms: YDR143C
Source: SGD:S000002550
Biotype: protein coding gene
Vps11
(Drosophila melanogaster)Gene
Name: Vacuolar protein sorting 11
Synonyms: CG32350, BcDNA:LD20292, VPS11, Vps11, vps11, vacuolar protein sorting 11
Source: FB:FBgn0052350
Biotype: protein coding gene
Trim24
(Mus musculus)Gene
Name: tripartite motif-containing 24
Synonyms: Tif1a, RIKEN cDNA A130082H20 gene, D430004I05Rik, EST AI447469, A130082H20Rik, transcriptional intermediary factor 1, alpha, TIF1alpha, AI447469, RIKEN cDNA D430004I05 gene
Source: MGI:109275
Biotype: protein coding gene
TUL1
(Saccharomyces cerevisiae)Gene
Name: Transmembrane Ubiquitin Ligase
Synonyms: YKL034W
Source: SGD:S000001517
Biotype: protein coding gene
Cbl
(Drosophila melanogaster)Gene
Name: Cbl proto-oncogene
Synonyms: D-Cbl L, v-Cbl, D-cblSHORT, dCbl, anon-WO0118547.68, Dcbl, F165, CG7043, D-CblL, Dv-cbl, Cbl, CBL, cbl, Dv-Cbl, Cbl proto-oncogene ortholog, D-cbl, d-cbl, DCbl, CG7037, D-Cbl, D-cblL, D-cblLONG, D-cblS, cable
Source: FB:FBgn0020224
Biotype: protein coding gene
Nosip
(Mus musculus)Gene
Name: nitric oxide synthase interacting protein
Synonyms: CGI-25, RIKEN cDNA 2310061K06 gene, 2310061K06Rik
Source: MGI:1913644
Biotype: protein coding gene
Ube3a
(Drosophila melanogaster)Gene
Name: Ubiquitin protein ligase E3A
Synonyms: CG6190, dube3A, dube3a, dUbe3a, dUbe3A, Ubiquitin-protein ligase E3A, Dube3A, UBE3A, Dube3a, ubiquitin protein ligase 3a, AS, Angelman syndrome, As, dUBE3A, das, Drosophila Angelman syndrome, ube3a, NM_140195.2, Ube3A
Source: FB:FBgn0061469
Biotype: protein coding gene
HLTF
(Homo sapiens)Gene
Name: helicase like transcription factor
Synonyms: HIP116, HLTF1, DNA-binding protein/plasminogen activator inhibitor-1 regulator, SNF2L3, SNF2-like 3, RING-type E3 ubiquitin transferase HLTF, HIP116A, RNF80, ZBU1, SMARCA3, sucrose nonfermenting protein 2-like 3, DNA-binding protein/plasminogen activator inhibitor 1 regulator, RING finger protein 80, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3, helicase-like transcription factor, sucrose nonfermenting-like 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3
Source: HGNC:11099
Biotype: protein coding gene
Fancf
(Mus musculus)Gene
Name: Fanconi anemia, complementation group F
Synonyms: RGD1561456
Source: MGI:3689889
Biotype: protein coding gene
C14B1.3
(Caenorhabditis elegans)Gene
Name: F-box domain-containing protein
Synonyms: CELE_C14B1.3
Source: WB:WBGene00007574
Biotype: protein coding gene
IPA1
(Saccharomyces cerevisiae)Gene
Name: Important for cleavage and PolyAdenylation
Synonyms: YJR141W
Source: SGD:S000003902
Biotype: protein coding gene
UBR1
(Saccharomyces cerevisiae)Gene
Name: Not Available
Synonyms: PTR1, YGR184C
Source: SGD:S000003416
Biotype: protein coding gene
Diap1
(Drosophila melanogaster)Gene
Name: Death-associated inhibitor of apoptosis 1
Synonyms: diap-1, Inhibitors of Apoptosis protein, E3, diap1, l(3)72CDe, l(3)72Dc, inhibitor of apoptosis, Drosophila Inhibitor of Apoptosis, Drosophila inhibitor of apoptosis 1, Drosophila Inhibitor of apoptosis protein 1, 1065/03, diap 1, Drosophila Inhibitor of Apoptosis Protein-1, diap1/thread, inhibitor of apoptosis-1, Drosophila thread/inhibitor of apoptosis protein-1, dIAP-1, DIAP I, drosophila inhibitor of apoptosis protein, DIAp, DIAP-1, Diap, DIAPI, Inhibitor of Apoptosis Protein 1, Drosophila inhibitor of apoptosis protein 1, Drosophila Inhibitor of Apoptosis Protein 1, Drosophila IAP1, IAP, Iap, CG12284, inhibitor of apoptosis protein 1, Diap-1/Th, l(3)j5C8, E(rpr)3-1, l(3)S030605b, l(3)S106503, Diap-1, D-IAP1, lethal (3) 72CDe, Drosophila inhibitor of apoptosis, Drosophila inhibitor-of-apoptosis protein 1, Drosophila Inhibitor of Apoptosis 1, Drosophila Inhibitor of Apoptosis Protein, DIAP, Inhibitor of Apoptosis 1, l(3)S030605, diap, Iap1, Drosophila inhibitor of apoptosis protein, IAP1, DIAP1, inhibitor of apoptotic protein 1, degradation of inhibitors of apoptosis, thread, Inhibitor of apoptosis 1, 0736/01, Thread, Diap1, DiAP1, th, TH, D-iap1, S048915, dIAP, dIAP1, dIap1
Source: FB:FBgn0260635
Biotype: protein coding gene
dx
(Drosophila melanogaster)Gene
Name: deltex
Synonyms: Dlx, Dx, CG3929, Deltex, DMDELTEX
Source: FB:FBgn0000524
Biotype: protein coding gene
CG13344
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: anon-EST:GressD1, anon-EST:GreesD1
Source: FB:FBgn0033884
Biotype: protein coding gene
TRIM25
(Homo sapiens)Gene
Name: tripartite motif containing 25
Synonyms: RING finger protein 147, E3 ubiquitin/ISG15 ligase TRIM25, tripartite motif-containing 25, ubiquitin/ISG15-conjugating enzyme TRIM25, zinc finger protein-147, EFP, zinc finger protein 147 (estrogen-responsive finger protein), tripartite motif-containing protein 25, estrogen-responsive finger protein, RNF147, Z147, RING-type E3 ubiquitin transferase TRIM25, RING-type E3 ubiquitin transferase, tripartite motif protein TRIM25, ZNF147
Source: HGNC:12932
Biotype: protein coding gene
PRP19
(Saccharomyces cerevisiae)Gene
Name: Pre-RNA Processing
Synonyms: YLL036C, PSO4
Source: SGD:S000003959
Biotype: protein coding gene