Version: 8.2.0Date: Wed Aug 27 2025
Category
SCD5
(Homo sapiens)Gene
Name: stearoyl-CoA desaturase 5
Synonyms: stearoyl-CoA desaturase 4, acyl-CoA-desaturase 4, FADS4, HSCD5, FLJ21032, SCD4, SCD2, stearoyl-CoA 9-desaturase, stearoyl-CoA desaturase 2, ACOD4, DFNA79
Source: HGNC:21088
Biotype: protein coding gene
Symbol: SCD5 (Hsa)
Symbol: SCD5
Gene Synopsis: In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (
SCD5
(Saccharomyces cerevisiae)Gene
Name: Suppressor of Clathrin Deficiency
Synonyms: YOR329C, SCD7, FTB1
Source: SGD:S000005856
Biotype: protein coding gene
Symbol: SCD5 (Sce)
Symbol: SCD5
Alleles: scd5-PP1D2 (Sce)...scd5-Δ448 (Sce)...scd5-Δ425 (Sce)...scd5-1 (Sce)...scd5-Δ (Sce)
scd5-D338
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286030
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-D338 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-D338
scd5-Δ
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000309870
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ
scd5-Δ9R
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000284276
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ9R (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ9R
scd5-Δ338
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000283370
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ338 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ338
scd5-1
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000284496
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-1 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-1
scd5-Δ425
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286792
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ425 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ425
scd5-Δ448
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286793
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ448 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ448
scd5-Δ467
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286794
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ467 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ467
scd5-Δ523
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286795
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ523 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ523
scd5-PP1Δ2
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286799
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-PP1Δ2 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-PP1Δ2
scd5-Δ32
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000284040
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-Δ32 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-Δ32
scd5-PP1D2
(Saccharomyces cerevisiae)Allele/Variant
Source: SGD:S000286031
Genes: SCD5 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: scd5-PP1D2 (Sce)
Genes: SCD5 (Sce)
Symbol: scd5-PP1D2
fat-5
(Caenorhabditis elegans)Gene
Name: FATty acid desaturase 5
Synonyms: W06D12.3, CELE_W06D12.3
Source: WB:WBGene00001397
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
CG15531
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: FA desaturase
Source: FB:FBgn0039755
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
fat-6
(Caenorhabditis elegans)Gene
Name: FATty acid desaturase 6
Synonyms: CELE_VZK822L.1, VZK822L.1
Source: WB:WBGene00001398
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
Desat1
(Drosophila melanogaster)Gene
Name: Desaturase 1
Synonyms: BEST:SD05462, Desat1, ds1, desaturase 1, desat1, Fad, fad, anon-WO0118547.726, desaturase1, DESAT1, CG5887, Dmel NPSE, Dmel NPSE Z9, anon-WO0118547.730, Fatty acid desaturase, l(3)S028813, desat, fatty acid desaturase, desaturase, stearoyl-CoA 9-desaturase, Stearoyl CoA desaturase, lethal (3) S028813
Source: FB:FBgn0086687
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
Desat2
(Drosophila melanogaster)Gene
Name: Desaturase 2
Synonyms: desat-2, ds2, Desat2, desat2, Fad, Dmel NPTQ Z9, desaturase2, Fatty acid desaturase, desat, Desaturase2, desaturase-2, 7-11HD, Dmel NPTQ, desaturase, desat2/Fad, CG5925, desat 2, 7,11-heptacosadiene modifier
Source: FB:FBgn0043043
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
CG8630
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Dmel SAMN
Source: FB:FBgn0038130
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
CG9743
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Dmel MSTE, anon-WO0118547.264
Source: FB:FBgn0039756
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
Fad2
(Drosophila melanogaster)Gene
Name: Fad2
Synonyms: CG7923, fad2, desatF, fad, desatF-alpha, Dmel CPVD, desaturase-F, dsat-F, DesatF
Source: FB:FBgn0029172
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
OLE1
(Saccharomyces cerevisiae)Gene
Name: OLEic acid requiring
Synonyms: MDM2, YGL055W
Source: SGD:S000003023
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
fat-7
(Caenorhabditis elegans)Gene
Name: FATty acid desaturase 7
Synonyms: F10D2.9, CELE_F10D2.9
Source: WB:WBGene00001399
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
CG9747
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Dmel MPSE
Source: FB:FBgn0039754
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
scd
(Xenopus tropicalis)Gene
Name: stearoyl-CoA desaturase (delta-9-desaturase)
Synonyms: fads5, stearoyl-CoA desaturase (delta-9-desaturase), scd, scd1, scdos
Source: Xenbase:XB-GENE-988226
Biotype: gene
Automated Gene Synopsis: Orthologous to several human genes including SCD5 (stearoyl-CoA desaturase 5).
Strict Orthology Symbols: SCD5
scd
(Danio rerio)Gene
Name: stearoyl-CoA desaturase (delta-9-desaturase)
Synonyms: SCD1
Source: ZFIN:ZDB-GENE-031106-3
Biotype: protein coding gene
Strict Orthology Symbols: SCD5
scdb
(Danio rerio)Gene
Name: stearoyl-CoA desaturase b
Synonyms: SCD2, zgc:112951
Source: ZFIN:ZDB-GENE-050522-12
Biotype: protein coding gene
Strict Orthology Symbols: SCD5
Gene Ontology
Source: GO:0016215
Synonyms:
- CoA desaturase activity
Branch: molecular function
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:1903966
Synonyms:
- monounsaturated fatty acid anabolism
- monounsaturated fatty acid biosynthesis
Branch: biological process
Genes: SCD5 (Hsa)
Source: DOID:0112160
Definition: An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the SCD5 gene on chromosome 4q21.22.
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0032896
Synonyms:
- palmitoyl-CoA delta9-desaturase activity
Branch: molecular function
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0004768
Synonyms:
- acyl-CoA desaturase
- delta(9)-desaturase activity
Branch: molecular function
Genes: SCD5 (Hsa)
Source: GO:2000370
Synonyms:
- positive regulation of clathrin coated pit-dependent endocytosis
- positive regulation of clathrin-mediated endocytosis
Branch: biological process
Genes: SCD5 (Sce)
Source: GO:0016717
Synonyms: Not Available
Branch: molecular function
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0030479
Synonyms:
- actin patch
Branch: cellular component
Genes: SCD5 (Sce)
Gene Ontology
Source: GO:0006636
Synonyms:
- fatty acid desaturation
- polyunsaturated fatty acid biosynthesis
Branch: biological process
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0008157
Synonyms: Not Available
Branch: molecular function
Genes: SCD5 (Sce)
Gene Ontology
Source: GO:0030866
Synonyms:
- actin cortex stabilization
- cortical actin cytoskeleton organisation
Branch: biological process
Genes: SCD5 (Sce)
Disease
Source: DOID:397
Definition: An intrinsic cardiomyopathy characterized by impaired ventricular filling, with normal or decreased diastolic volume of either or both ventricles typically resulting from increased stiffness of the myocardium.
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0009306
Synonyms:
- glycoprotein secretion
- protein secretion during cell fate commitment
Branch: biological process
Genes: SCD5 (Sce)
Gene Ontology
Source: GO:0006633
Synonyms:
- fatty acid anabolism
- fatty acid biosynthesis
Branch: biological process
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0005506
Synonyms:
- iron binding
Branch: molecular function
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0006631
Synonyms:
- fatty acid metabolism
Branch: biological process
Genes: SCD5 (Hsa)
Gene Ontology
Source: GO:0006897
Synonyms:
- endocytic import into cell
- nonselective vesicle endocytosis
Branch: biological process
Genes: SCD5 (Sce)
Gene Ontology
Source: GO:0005783
Synonyms:
- ER
Branch: cellular component
Genes: SCD5 (Hsa)
(GRCh38)4:82636609C>T
(Homo sapiens)Allele/Variant
Source: rs755864702
Genes: SCD5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)4:82636609C>T
(GRCh38)4:82680854T>C
(Homo sapiens)Allele/Variant
Source: NC_000004.12:g.82680854T>C
Genes: SCD5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)4:82680854T>C
(GRCh38)4:82631385C>T
(Homo sapiens)Allele/Variant
Source: rs150319742
Genes: SCD5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)4:82631385C>T
(GRCh38)4:82798394C>T
(Homo sapiens)Allele/Variant
Source: rs112255809
Genes: SCD5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)4:82798394C>T