Version: 8.1.0Date: Fri Apr 18 2025
Category
alg-2
(Caenorhabditis elegans)Gene
Name: Argonaute (plant)-Like Gene 2
Synonyms: CELE_T07D3.7, T07D3.7, T07D3
Source: WB:WBGene00000106
Biotype: protein coding gene
Symbol: alg-2 (Cel)
Symbol: alg-2
Gene Synopsis: alg-2 encodes a PAZ and PIWI-domain containing protein that is a member of the highly conserved eukaryotic...RDE-1/AGO1/PIWI family of proteins that regulate posttranscriptional gene silencing (PTGS); ALG-2 functions...events by positively regulating expression of small temporal RNAs (stRNAs) encoded by lin-4 and let-7; ALG...1 are also required for RNAi in the germ line, although they are not required for RNAi in the soma; ALG
Cross References: alg-2...WB:alg-2...alg-2
Alg-2
(Drosophila melanogaster)Gene
Name: Apoptosis-linked gene-2
Synonyms: CG17661, ALG-2, apoptosis-linked gene-2, Apoptosis-linked gene-2, DALG-2, CG40410
Source: FB:FBgn0086378
Biotype: protein coding gene
Symbol: Alg-2 (Dme)
Symbol: Alg-2
Synonyms: ALG-2...ALG-2...ALG-2
Alleles: Alg-2
Alg-2RNAi.UAS
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0349241
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Construct Knockdown Component: Alg-2 (Dme)
Name: Alg-2RNAi.UAS
Symbol: Alg-2RNAi.UAS
Alg-2GD3522
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0263598
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Construct Knockdown Component: Alg-2 (Dme)
Name: Alg-2GD3522
Symbol: Alg-2GD3522
Alg-2UAS.cTa
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0195113
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Name: Alg-2UAS.cTa
Construct Expressed Component: Alg-2 (Dme)
Symbol: Alg-2UAS.cTa
Constructs: UAS-ALG-2
Alg-2NIG.17661R
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0272677
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Construct Knockdown Component: Alg-2 (Dme)
Name: Alg-2NIG.17661R
Symbol: Alg-2NIG.17661R
Alg-2MI00909
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0247083
Genes: Alg-2 (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Gene Synonyms: ALG-2
Genes: Alg-2 (Dme)
Name: Alg-2MI00909
Symbol: Alg-2MI00909
Alg-2MI00909-GFSTF.0
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0314606
Genes: Alg-2 (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Alg-2
Gene Synonyms: ALG-2
Genes: Alg-2 (Dme)
Name: Alg-2MI00909-GFSTF.0
Symbol: Alg-2MI00909-GFSTF.0
Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2.
(Caenorhabditis elegans)HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by WB
ID: WB:Microarray_Study.WBPaper00040911.ce.mr,
Tags: RNA interference
Summary: Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2.
Symbol: Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2.
Name: Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2.
Pdcd6
(Mus musculus)Gene
Name: programmed cell death 6
Synonyms: ALG-2, alg-2, AV299538, expressed sequence AV299538, Alg2, MA-3, apoptosis linked gene 2, PS2
Source: MGI:109283
Biotype: protein coding gene
Synonyms: ALG-2...alg-2...ALG-2...alg-2...alg-2...ALG-2...alg-2
Strict Orthology Symbols: Alg-2
PDCD6
(Homo sapiens)Gene
Name: programmed cell death 6
Synonyms: apoptosis-linked gene 2 protein, apoptosis-linked gene 2 protein homolog, PEF1B, programmed cell death protein 6, ALG2, apoptosis-linked gene-2, probable calcium-binding protein ALG-2, MGC119050, MGC9123, ALG-2, FLJ42309, FLJ46208, MGC111017
Source: HGNC:8765
Biotype: protein coding gene
Synonyms: ALG-2...probable calcium-binding protein ALG-2...ALG-2...probable calcium-binding protein ALG-2...ALG-2
Strict Orthology Symbols: Alg-2
PDCD6IP
(Homo sapiens)Gene
Name: programmed cell death 6 interacting protein
Synonyms: dopamine receptor interacting protein 4, Alix, HP95, MCPH29, ALG-2-interacting protein 1, MGC17003, ALG-2 interacting protein X, PDCD6-interacting protein, AIP1, ALG-2 interacting protein 1, DRIP4, programmed cell death 6-interacting protein, apoptosis-linked gene 2-interacting protein X, ALG-2-interacting protein X
Source: HGNC:8766
Biotype: protein coding gene
Synonyms: ALG-2 interacting protein X...ALG-2 interacting protein 1...ALG-2-interacting protein 1...ALG-2 interacting protein X...ALG-2 interacting protein 1...ALG-2-interacting protein X
AGO1
(Homo sapiens)Gene
Name: argonaute RISC component 1
Synonyms: putative RNA-binding protein Q99, GERP95, Golgi Endoplasmic Reticulum protein 95 kDa, argonaute 1, RISC catalytic component, argonaute RISC catalytic component 1, hAgo1, argonaute 1, argonaute1, protein argonaute-1, eIF-2C 1, Q99, eukaryotic translation initiation factor 2C, 1, NEDLBAS, DKFZp686M13167, EIF2C, eIF2C 1, EIF2C1
Source: HGNC:3262
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Pdcd6ip
(Rattus norvegicus)Gene
Name: programmed cell death 6 interacting protein
Synonyms: ALG-2-interacting protein 1, RGD1561176, ALG-2 interacting protein X, Alix, AIP1, ALG-2 interacting protein 1, programmed cell death 6-interacting protein
Source: RGD:68357
Biotype: protein coding gene
Synonyms: ALG-2 interacting protein X...ALG-2 interacting protein 1...ALG-2-interacting protein 1...ALG-2 interacting protein X...ALG-2 interacting protein 1
AGO2
(Homo sapiens)Gene
Name: argonaute RISC catalytic component 2
Synonyms: protein slicer, LESKRES, LINC00980, argonaute2, PPD, PAZ Piwi domain protein, CASC7, hAgo2, eIF-2C 2, MGC3183, argonaute 2, protein argonaute-2, long intergenic non-protein coding RNA 980, eukaryotic translation initiation factor 2C, 2, Q10, argonaute 2, RISC catalytic component, CTA-204B4.6, cancer susceptibility candidate 7 (non-protein coding), eIF2C 2, EIF2C2, cancer susceptibility candidate 7
Source: HGNC:3263
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
AGO3
(Homo sapiens)Gene
Name: argonaute RISC catalytic component 3
Synonyms: EIF2C3, eukaryotic translation initiation factor 2C, 3, argonaute3, hAgo3, argonaute 3, RISC catalytic component, argonaute 3, MGC86946, FLJ12765, eIF-2C 3, protein argonaute-3, eIF2C 3
Source: HGNC:18421
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
AGO4
(Homo sapiens)Gene
Name: argonaute RISC component 4
Synonyms: EIF2C4, eukaryotic translation initiation factor 2C, 4, eIF-2C 4, argonaute4, protein argonaute-4, hAgo4, argonaute 4, RISC catalytic component, argonaute RISC catalytic component 4, eIF2C 4, argonaute 4
Source: HGNC:18424
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Pdcd6
(Rattus norvegicus)Gene
Name: programmed cell death 6
Synonyms: apoptosis-linked gene 2 protein homolog, LOC308061, ALG-2, programmed cell death protein 6
Source: RGD:1311239
Biotype: protein coding gene
Synonyms: ALG-2...ALG-2...ALG-2
Strict Orthology Symbols: Alg-2
ALiX
(Drosophila melanogaster)Gene
Name: ALG-2 interacting protein X
Synonyms: CG12876, DAIP1, ALIX, AliX, Alix, Aip1, AIP1, alix, ALG-2 interacting protein 1, Snf7, apoptosis linked gene 2 interacting X
Source: FB:FBgn0086346
Biotype: protein coding gene
Gene Synopsis: ALG-2 interacting protein X (ALiX) encodes an adaptor protein implicated in multiple cellular processes
Synonyms: ALG-2 interacting protein 1...ALG-2 interacting protein 1
Ago2
(Rattus norvegicus)Gene
Name: argonaute RISC catalytic component 2
Synonyms: protein slicer, eukaryotic translation initiation factor 2C, 2, Gerp95, argonaute2, golgi ER protein 95 kDa, argonaute 2, RISC catalytic component, eukaryotic translation initiation factor 2C 2, Eif2c2, eIF-2C 2, eIF2C 2, protein argonaute-2
Source: RGD:621255
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
ago4
(Danio rerio)Gene
Name: argonaute RISC component 4
Synonyms: eif2c4, fd14f04, Ago4, wu:fd14f04
Source: ZFIN:ZDB-GENE-030131-5357
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
M04F3.4
(Caenorhabditis elegans)Gene
Name: EF-hand domain-containing protein
Synonyms: CELE_M04F3.4
Source: WB:WBGene00019770
Biotype: protein coding gene
Strict Orthology Symbols: Alg-2
Ago3
(Rattus norvegicus)Gene
Name: argonaute RISC catalytic component 3
Synonyms: eukaryotic translation initiation factor 2C, 3, Eif2c3, LOC313593, argonaute 3, RISC catalytic component, protein argonaute-3
Source: RGD:1309163
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
AGO1
(Drosophila melanogaster)Gene
Name: Argonaute-1
Synonyms: Argonaute 1, Argonaute protein 1, ago1-1, Ago-1, argonaute 1, mRNA-like ncRNA in embryogenesis 20, l(2)k08121, anon-WO0257455.29, dAGO1, Argonaute, Agp1, l(2)04845, l(2)4845, MRE20, argonaute-1, ago1, CG6671, Ago, ago-1, argonaute1, ARGONAUTE-1, dAgo1, dmAgo1, Dm Ago1, Ago1, AGO-1, DmAgo1, Argonaute1, l(2)k00208
Source: FB:FBgn0262739
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago1
(Mus musculus)Gene
Name: argonaute RISC catalytic subunit 1
Synonyms: eukaryotic translation initiation factor 2C, 1, argonaute 1, Eif2c1
Source: MGI:2446630
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago4
(Rattus norvegicus)Gene
Name: argonaute RISC component 4
Synonyms: eukaryotic translation initiation factor 2C, 4, protein argonaute-4-like, Eif2c4, LOC102554576, protein argonaute-4, LOC298533, argonaute RISC catalytic component 4, argonaute 4, RISC catalytic component
Source: RGD:1304583
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago1
(Rattus norvegicus)Gene
Name: argonaute RISC component 1
Synonyms: eukaryotic translation initiation factor 2C, 1, argonaute 1, RISC catalytic component, argonaute RISC catalytic component 1, LOC313594, Eif2c1, protein argonaute-1
Source: RGD:1304619
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago4
(Mus musculus)Gene
Name: argonaute RISC catalytic subunit 4
Synonyms: expressed sequence AI481660, AI481660, eukaryotic translation initiation factor 2C, 4, Eif2c4, 5730550L01Rik, argonaute 4, RIKEN cDNA 5730550L01 gene
Source: MGI:1924100
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
pdcd6
(Danio rerio)Gene
Name: programmed cell death 6
Synonyms: zgc:63952
Source: ZFIN:ZDB-GENE-040426-1307
Biotype: protein coding gene
Strict Orthology Symbols: Alg-2
ago1
(Danio rerio)Gene
Name: argonaute RISC component 1
Synonyms: Ago1, si:ch211-119n15.3, eif2c1
Source: ZFIN:ZDB-GENE-110606-3
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago3
(Mus musculus)Gene
Name: argonaute RISC catalytic subunit 3
Synonyms: AW048688, eukaryotic translation initiation factor 2C, 3, Eif2c3, C130014L07Rik, argonaute 3, RIKEN cDNA C130014L07 gene, expressed sequence AW048688, eIF2C3
Source: MGI:2446634
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
ago3b
(Danio rerio)Gene
Name: argonaute RISC catalytic component 3b
Synonyms: eif2c3, eif2c3b, si:dkey-3n22.3, Ago3b, sb:eu332
Source: ZFIN:ZDB-GENE-060503-452
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
Ago2
(Mus musculus)Gene
Name: argonaute RISC catalytic subunit 2
Synonyms: expressed sequence AI225898, AW546247, mKIAA1567, RIKEN cDNA 2310051F07 gene, Eif2c2, 1110029L17Rik, argonaute 2, expressed sequence AW546247, 2310051F07Rik, eukaryotic translation initiation factor 2C, 2, RIKEN cDNA 1110029L17 gene, AI225898, AL022874, expressed sequence AL022874, eIF2C 2
Source: MGI:2446632
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
ago2
(Danio rerio)Gene
Name: argonaute RISC catalytic component 2
Synonyms: Ago2, eif2c2
Source: ZFIN:ZDB-GENE-110606-6
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
ago3a
(Danio rerio)Gene
Name: argonaute RISC catalytic component 3a
Synonyms: Ago3a, eif2c3a, sb:eu416, sb:eu275
Source: ZFIN:ZDB-GENE-051107-16
Biotype: protein coding gene
Strict Orthology Symbols: alg-2
mir-2209.3
(Caenorhabditis elegans)Gene
Name: MIcro RNA 2209.3
Synonyms: CELE_Y55F3AM.20, mir-2209c, Cel-Bantam-P5c, cel-mir-2209c, Y55F3AM.20
Source: WB:WBGene00194826
Biotype: miRNA gene
Gene Synopsis: Is affected by alg-2 and alg-5 based on RNA-seq studies.
PEF1
(Saccharomyces cerevisiae)Gene
Name: Penta-EF-Hand protein
Synonyms: YGR058W
Source: SGD:S000003290
Biotype: protein coding gene
Strict Orthology Symbols: Alg-2
mir-5552
(Caenorhabditis elegans)Gene
Name: MIcro RNA 5552
Synonyms: CELE_Y59A8B.39, Y59A8B.39, cel-mir-5552
Source: WB:WBGene00219233
Biotype: miRNA gene
Gene Synopsis: Is affected by several genes including mrps-5; alg-1; and alg-2 based on RNA-seq studies.
Source: GO:0070551
Synonyms:
- argonaute endoribonuclease activity
Branch: molecular function
Genes: alg-2 (Cel)
ago3
(Xenopus tropicalis)Gene
Name: argonaute 3, RISC catalytic component
Synonyms: LOC108709549, ago3, Argonaute3, argonaute 3, RISC catalytic component, argonaute 3, LOC108708211
Source: Xenbase:XB-GENE-6462752
Biotype: gene
Strict Orthology Symbols: alg-2
ago4
(Xenopus tropicalis)Gene
Name: argonaute 4, RISC catalytic component
Synonyms: argonaute-4, eif2c4, Argonaute4, ago4, argonaute 4, RISC catalytic component
Source: Xenbase:XB-GENE-1006882
Biotype: gene
Strict Orthology Symbols: alg-2
ago2
(Xenopus tropicalis)Gene
Name: argonaute 2, RISC catalytic component
Synonyms: ago2, argonaute 2, RISC catalytic component, Argonaute2, LOC108695459, argonaute 2, eif2c2
Source: Xenbase:XB-GENE-1001916
Biotype: gene
Strict Orthology Symbols: alg-2
pdcd6
(Xenopus tropicalis)Gene
Name: programmed cell death 6
Synonyms: programmed cell death 6, pdcd6
Source: Xenbase:XB-GENE-960916
Biotype: gene
Strict Orthology Symbols: Alg-2
mir-1824
(Caenorhabditis elegans)Gene
Name: MIcro RNA 1824
Synonyms: CELE_Y87G2A.21, Y87G2A.21, cel-mir-1824
Source: WB:WBGene00077718
Biotype: miRNA gene
Gene Synopsis: Is affected by several genes including hrpk-1; alg-1; and alg-2 based on RNA-seq studies.
mir-2208.2
(Caenorhabditis elegans)Gene
Name: MIcro RNA 2208.2
Synonyms: Cel-Mir-2208-P2, mir-2208b, Y55F3AM.17, CELE_Y55F3AM.17, cel-mir-2208b
Source: WB:WBGene00194823
Biotype: miRNA gene
Gene Synopsis: Is affected by several genes including hrpk-1; alg-1; and alg-2 based on RNA-seq studies.
mir-1020
(Caenorhabditis elegans)Gene
Name: MIcro RNA 1020
Synonyms: CELE_T16G12.11, T16G12.11, cel-mir-1020
Source: WB:WBGene00050922
Biotype: miRNA gene
Gene Synopsis: Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies.
mir-4805
(Caenorhabditis elegans)Gene
Name: MIcro RNA 4805
Synonyms: CELE_K02E7.13, cel-mir-4805, K02E7.13
Source: WB:WBGene00195238
Biotype: miRNA gene
Gene Synopsis: Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies.
Pdcd6tm1a(EUCOMM)Hmgu
(Mus musculus)Allele/Variant
Source: MGI:4451851
Genes: Pdcd6 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: ALG-2...alg-2
Source: GO:0016892
Synonyms:
- endoribonuclease activity, producing 3'-phosphomonoesters
- endoribonuclease activity, producing other than 5'-phosphomonoesters
Branch: molecular function
Genes: alg-2 (Cel)
mir-1823
(Caenorhabditis elegans)Gene
Name: MIcro RNA 1823
Synonyms: CELE_T07D10.9, Cel-Mir-1823-v1, Cel-Mir-1823-v2, cel-mir-1823, T07D10.9
Source: WB:WBGene00077717
Biotype: miRNA gene
Gene Synopsis: Is affected by alg-2 based on RNA-seq studies.