Version: 8.0.0
Date: Tue Jan 28 2025
9,842 results for bach1

Bach1

(Mus musculus)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: RIKEN cDNA 6230421P05 gene, AI323795, expressed sequence AI323795, 6230421P05Rik
Source: MGI:894680
Biotype: protein coding gene
Symbol: Bach1 (Mmu)
Symbol: Bach1
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Strict Orthology Symbols: bach1
Alleles: Bach1 (Mmu)...Bach1 (Mmu)...Bach1 (Mmu)...Bach1 (Mmu)...Bach1 (Mmu)

Bach1

(Rattus norvegicus)
Gene
Name: BTB domain and CNC homolog 1
Synonyms: LOC103690154, LOC100911490, BTB and CNC homology 1 transcription factor, transcription regulator protein BACH1-like, BTB and CNC homology 1, BTB and CNC homology 1, basic leucine zipper transcription factor 1, LOC304127, transcription regulator protein BACH1
Source: RGD:1306693
Biotype: protein coding gene
Symbol: Bach1 (Rno)
Symbol: Bach1
Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1); INTERACTS WITH 17beta-estradiol; 4-amino-2,6
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Synonyms: transcription regulator protein BACH1
Strict Orthology Symbols: bach1

BACH1

(Homo sapiens)
Gene
Name: BTB domain and CNC homolog 1
Synonyms: HA2303, BTBD24, BTB and CNC homology 1, basic leucine zipper transcription factor 1, basic region leucine zipper transcriptional regulator BACH1, BACH-1, BTB and CNC homolog 1, AP000240.4, transcription regulator protein BACH1
Source: HGNC:935
Biotype: protein coding gene
Symbol: BACH1 (Hsa)
Symbol: BACH1
Synonyms: basic region leucine zipper transcriptional regulator BACH1...transcription regulator protein BACH1
Strict Orthology Symbols: bach1

bach1

(Xenopus tropicalis)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: BTB and CNC homology 1, basic leucine zipper transcription factor 1, bach1
Source: Xenbase:XB-GENE-957116
Biotype: gene
Symbol: bach1 (Xtr)
Symbol: bach1
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Synonyms: bach1...bach1...bach1
Strict Orthology Symbols: bach1.L...Bach1...bach1a...bach1b...BACH1

bach1a

(Danio rerio)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
Synonyms: zgc:136739
Source: ZFIN:ZDB-GENE-060421-7601
Biotype: protein coding gene
Symbol: bach1a (Dre)
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Strict Orthology Symbols: bach1
Symbol: bach1a

bach1b

(Danio rerio)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
Synonyms: zgc:112205, bach1
Source: ZFIN:ZDB-GENE-050522-220
Biotype: protein coding gene
Symbol: bach1b (Dre)
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Synonyms: bach1...bach1...bach1
Strict Orthology Symbols: bach1
Symbol: bach1b

BACH1-IT2

(Homo sapiens)
Gene
Name: BACH1 intronic transcript 2
Synonyms: Not Available
Source: HGNC:40007
Biotype: ncRNA gene
Symbol: BACH1-IT2 (Hsa)
Symbol: BACH1-IT2

BACH1-IT3

(Homo sapiens)
Gene
Name: BACH1 intronic transcript 3
Synonyms: NCRNA00097, C21orf8
Source: HGNC:16455
Biotype: ncRNA gene
Symbol: BACH1-IT3 (Hsa)
Symbol: BACH1-IT3

BACH1-AS1

(Homo sapiens)
Gene
Name: BACH1 antisense RNA 1
Synonyms: Not Available
Source: HGNC:40008
Biotype: ncRNA gene
Symbol: BACH1-AS1 (Hsa)
Symbol: BACH1-AS1

bach1.L

(Xenopus laevis)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: bach1.L, BTB and CNC homology 1, basic leucine zipper transcription factor 1
Source: Xenbase:XB-GENE-17343628
Biotype: gene
Symbol: bach1.L (Xla)
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Strict Orthology Symbols: bach1
Symbol: bach1.L

bach1.S

(Xenopus laevis)
Gene
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: bach1.S, BTB and CNC homology 1, basic leucine zipper transcription factor 1
Source: Xenbase:XB-GENE-6486632
Biotype: gene
Symbol: bach1.S (Xla)
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Strict Orthology Symbols: bach1
Symbol: bach1.S

Bach1em1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7288424
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em1Smoc

Bach1em2Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7288425
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em2Smoc

Bach1tm1a(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:5009633
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1tm1a(EUCOMM)Hmgu

Bach1em3Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7764477
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em3Smoc

Bach1tm1.1(KOMP)Vlcg

(Mus musculus)
Allele/Variant
Source: MGI:5471267
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1tm1.1(KOMP)Vlcg

Bach1tm1Igar

(Mus musculus)
Allele/Variant
Source: MGI:3590153
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1tm1Igar

Bach1em1Cya

(Mus musculus)
Allele/Variant
Source: MGI:7582535
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em1Cya

Bach1em2Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7376257
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em2Gpt

Bach1em2Cya

(Mus musculus)
Allele/Variant
Source: MGI:7582536
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em2Cya

Bach1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7376256
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1em1Gpt

Bach1tm1(KOMP)Vlcg

(Mus musculus)
Allele/Variant
Source: MGI:4881112
Genes: Bach1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Bach1 (Mmu)
Genes: Bach1 (Mmu)
Symbol: Bach1tm1(KOMP)Vlcg

Bach1tm1.1(KOMP)Vlcg/Bach1+ [background:] B6N(Cg)-Bach1tm1.1(KOMP)Vlcg/J

(Mus musculus)
Model
Id: MGI:5763836
Synonyms: Not Available
Symbol: Bach1/Bach1<+> [background:] B6N(Cg)-Bach1/J (Mmu)
Genes: Bach1 (Mmu)
Alleles: Bach1 (Mmu)
Name: Bach1/Bach1<+> [background:] B6N(Cg)-Bach1/J

bach1astl663/stl663 (TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-241118-9
Synonyms: Not Available
Symbol: bach1a (TU) (Dre)
Genes: bach1a (Dre)

Bach1tm1Igar/Bach1tm1Igar [background:] involves: 129P2/OlaHsd * C57BL/6J

(Mus musculus)
Model
Id: MGI:3590336
Synonyms: Not Available
Symbol: Bach1/Bach1 [background:] involves: 129P2/OlaHsd * C57BL/6J (Mmu)
Genes: Bach1 (Mmu)
Alleles: Bach1 (Mmu)
Name: Bach1/Bach1 [background:] involves: 129P2/OlaHsd * C57BL/6J

Bach1tm1.1(KOMP)Vlcg/Bach1tm1.1(KOMP)Vlcg [background:] B6N(Cg)-Bach1tm1.1(KOMP)Vlcg/J

(Mus musculus)
Model
Id: MGI:5763837
Synonyms: Not Available
Symbol: Bach1/Bach1 [background:] B6N(Cg)-Bach1/J (Mmu)
Genes: Bach1 (Mmu)
Alleles: Bach1 (Mmu)
Name: Bach1/Bach1 [background:] B6N(Cg)-Bach1/J

Bach1tm1Igar/Bach1tm1Igar [background:] B6.129P2-Bach1tm1Igar

(Mus musculus)
Model
Id: MGI:3718512
Synonyms: Not Available
Symbol: Bach1/Bach1 [background:] B6.129P2-Bach1 (Mmu)
Genes: Bach1 (Mmu)
Alleles: Bach1 (Mmu)
Name: Bach1/Bach1 [background:] B6.129P2-Bach1

bach1bstl666/stl666 (TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-241118-11
Synonyms: Not Available
Symbol: bach1b (TU) (Dre)
Genes: bach1b (Dre)

bach1bstl665/stl665 (TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-241118-10
Synonyms: Not Available
Symbol: bach1b (TU) (Dre)
Genes: bach1b (Dre)

CG15725

(Drosophila melanogaster)
Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0030417
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human BACH1 (BTB domain and CNC homolog 1).
Strict Orthology Symbols: bach1

brip1

(Xenopus tropicalis)
Gene
Name: BRCA1 interacting DNA helicase 1
Synonyms: brip1, fancj, BRCA1 interacting DNA helicase 1, bach1
Source: Xenbase:XB-GENE-492370
Biotype: gene
Synonyms: bach1...bach1...bach1

brip1.L

(Xenopus laevis)
Gene
Name: BRCA1 interacting DNA helicase 1
Synonyms: fancj, BRCA1 interacting DNA helicase 1, brip1.L, bach1
Source: Xenbase:XB-GENE-866151
Biotype: gene
Synonyms: bach1...bach1...bach1

BRIP1

(Homo sapiens)
Gene
Name: BRCA1 interacting DNA helicase 1
Synonyms: Fanconi anemia group J protein, FANCJ, BRCA1-interacting protein C-terminal helicase 1, BRCA1/BRCA2-associated helicase 1, BRCA1-binding helicase-like protein BACH1, MGC126521, MGC126523, BRCA1-associated C-terminal helicase 1, BACH1, BRCA1-interacting protein 1, FANCJ helicase, BRCA1 interacting helicase 1, ATP-dependent RNA helicase BRIP1, OF, FLJ90232, BRCA1 interacting protein C-terminal helicase 1, DNA 5'-3' helicase FANCJ
Source: HGNC:20473
Biotype: protein coding gene
Synonyms: BACH1...BRCA1-binding helicase-like protein BACH1...BACH1

Brip1

(Mus musculus)
Gene
Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: 8030460J03Rik, RIKEN cDNA 8030460J03 gene, 3110009N10Rik, BACH1, RIKEN cDNA 3110009N10 gene
Source: MGI:2442836
Biotype: protein coding gene
Synonyms: BACH1...BACH1

TU + CRISPR1-bach1a + CRISPR1-bach1b + CRISPR2-bach1a + CRISPR2-bach1b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-241115-6
Synonyms: Tuebingen
Genes: bach1b (Dre)...bach1a (Dre)

AB + MO1-bach1a + MO3-bach1b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160104-13
Synonyms: Not Available
Genes: bach1b (Dre)...bach1a (Dre)

stl663

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-230818-2
Genes: bach1a (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: bach1a (Dre)

ligand-activated transcription factor activity

Gene Ontology
Source: GO:0098531
Synonyms:
  • direct ligand regulated sequence-specific DNA binding transcription factor activity
  • transcription factor activity, direct ligand regulated sequence-specific DNA binding
Branch: molecular function
Genes: BACH1 (Hsa)...Bach1 (Mmu)...Bach1 (Rno)

stl666

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-230818-3
Genes: bach1b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: bach1
Genes: bach1b (Dre)

stl665

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-230821-5
Genes: bach1b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: bach1
Genes: bach1b (Dre)

AB + MO3-bach1b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160104-12
Synonyms: Not Available
Genes: bach1b (Dre)

uom301b

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-240626-7
Genes: bach1b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: bach1
Genes: bach1b (Dre)

AB + MO1-bach1a

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160104-10
Synonyms: Not Available
Genes: bach1a (Dre)

uom301a

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-240626-6
Genes: bach1a (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: bach1a (Dre)

AB + MO1-bach1b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160104-11
Synonyms: Not Available
Genes: bach1b (Dre)

WT + MO1-bach1b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-24701
Synonyms: Not Available
Genes: bach1b (Dre)

Microglial metabolism mediated by BACH1 orchestrates astrogenesis during brain development

(Mus musculus)
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by MGI
ID: ArrayExpress:GSE227957
Tags: WT vs. mutant, genotype
Summary: Purpose: To gain futher insight into how microglia-derived BACH1 regulates microglial metabolism and astrogenesis, RNA-seq was used to analyze the genome-wide changes resulting from isolated microglia of E16 microglial BACH1 conditional knock out mice and littermate wild-type. Methods: mRNA from E16 isolated microglia of Bach1fl/fl and Bach1cKO-Cx3 mice was extracted. Specifically, Agilent 2100 Bioanalyze was used to quality controlled and quantified. then, mRNA was converted to cDNA and bound the library. RNA-sequencing analysis was used by the Illumina HiSeq 2500 platform in Annoroad Genomics. Results: Approximately one thousand transcripts showed differential expression between the Bach1fl/fl and Bach1cKO-Cx3 mice brain microglia, with a fold change >= 3 and p value <0.05. Geneontology analysis of the downregulated genes were enriched in terms related to cell proliferation, glial cell differentiation and cell communication and upregulated genes were enriched in terms related to negative regulation of cell proliferation, negative regulation of astrocyte differentiation and glial cell fate commitment. These results reflected microglia BACH1 plays roles in cortex development. Conclusions: Microglia BACH1 RNA-seq would provide a overall understanding how microglia-derived BACH1regulates astrogenesis during brain development. mRNA profiles of E16 Bach1fl/fl and Bach1cKO-Cx3 mice were generated by deep sequencing, in triplicate, using Illumina HiSeq 2500.
Symbol: Microglial metabolism mediated by BACH1 orchestrates astrogenesis during brain development
Name: Microglial metabolism mediated by BACH1 orchestrates astrogenesis during brain development

Brip1Gt(RRI409)Byg

(Mus musculus)
Allele/Variant
Source: MGI:4129733
Genes: Brip1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: BACH1

Brip1em2Peco

(Mus musculus)
Allele/Variant
Source: MGI:7616326
Genes: Brip1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: BACH1

Brip1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7296007
Genes: Brip1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: BACH1