Version: 8.0.0
Date: Tue Jan 28 2025
5,582 results for ccdc88c

CCDC88C

(Homo sapiens)
Gene
Name: coiled-coil domain containing 88C
Synonyms: hDaple, DAPLE, HYC, FLJ00354, HkRP2, coiled-coil domain-containing protein 88C, hook-related protein 2, Dvl-associating protein with a high frequency of leucine residues, SCA40, HYC1, spinocerebellar ataxia 40, KIAA1509
Source: HGNC:19967
Biotype: protein coding gene
Symbol: CCDC88C (Hsa)
Symbol: CCDC88C
Strict Orthology Symbols: ccdc88c

Ccdc88c

(Rattus norvegicus)
Gene
Name: coiled-coil domain containing 88C
Synonyms: RGD1307429, similar to KIAA1509 protein, LOC362770
Source: RGD:1307429
Biotype: protein coding gene
Symbol: Ccdc88c (Rno)
Symbol: Ccdc88c
Gene Synopsis: Orthologous to human CCDC88C (coiled-coil domain containing 88C); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine
Automated Gene Synopsis: Orthologous to human CCDC88C (coiled-coil domain containing 88C).
Strict Orthology Symbols: ccdc88c

ccdc88c

(Danio rerio)
Gene
Name: coiled-coil domain containing 88C
Synonyms: zDAPLE
Source: ZFIN:ZDB-GENE-100419-3
Biotype: protein coding gene
Symbol: ccdc88c (Dre)
Symbol: ccdc88c
Automated Gene Synopsis: Orthologous to human CCDC88C (coiled-coil domain containing 88C).
Strict Orthology Symbols: ccdc88c

Ccdc88c

(Mus musculus)
Gene
Name: coiled-coil domain containing 88C
Synonyms: Daple, expressed sequence AW324073, RGD1307429, RIKEN cDNA 0610010D24 gene, AW324073, AV000935, expressed sequence AV000935, 0610010D24Rik
Source: MGI:1915589
Biotype: protein coding gene
Symbol: Ccdc88c (Mmu)
Symbol: Ccdc88c
Automated Gene Synopsis: Orthologous to human CCDC88C (coiled-coil domain containing 88C).
Strict Orthology Symbols: ccdc88c
Alleles: Ccdc88c (Mmu)...Ccdc88c (Mmu)...Ccdc88c (Mmu)...Ccdc88c (Mmu)

ccdc88c

(Xenopus tropicalis)
Gene
Name: coiled-coil domain containing 88C
Synonyms: daple, ccdc88c, LOC108699825, LOC108698716, coiled-coil domain containing 88C, XDal
Source: Xenbase:XB-GENE-1033686
Biotype: gene
Symbol: ccdc88c
Symbol: ccdc88c (Xtr)
Automated Gene Synopsis: Orthologous to human CCDC88C (coiled-coil domain containing 88C).
Synonyms: ccdc88c...ccdc88c...ccdc88c
Strict Orthology Symbols: ccdc88c

CCDC88C-DT

(Homo sapiens)
Gene
Name: CCDC88C divergent transcript
Synonyms: uncharacterized LOC105370625, LOC105370625
Source: HGNC:55438
Biotype: ncRNA gene
Symbol: CCDC88C-DT (Hsa)
Symbol: CCDC88C-DT

Ccdc88cem1Cya

(Mus musculus)
Allele/Variant
Source: MGI:7582782
Genes: Ccdc88c (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Ccdc88c (Mmu)
Genes: Ccdc88c (Mmu)
Symbol: Ccdc88cem1Cya

Ccdc88ctm1Mat

(Mus musculus)
Allele/Variant
Source: MGI:6470667
Genes: Ccdc88c (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Ccdc88c (Mmu)
Genes: Ccdc88c (Mmu)
Symbol: Ccdc88ctm1Mat

Ccdc88ctm1(KOMP)Mbp

(Mus musculus)
Allele/Variant
Source: MGI:5141808
Genes: Ccdc88c (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Ccdc88c (Mmu)
Genes: Ccdc88c (Mmu)
Symbol: Ccdc88ctm1(KOMP)Mbp

Ccdc88ctm1.1(KOMP)Mbp

(Mus musculus)
Allele/Variant
Source: MGI:5548562
Genes: Ccdc88c (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Ccdc88c (Mmu)
Genes: Ccdc88c (Mmu)
Symbol: Ccdc88ctm1.1(KOMP)Mbp

ccdc88cbu9/bu9

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210923-3
Synonyms: Not Available
Symbol: ccdc88c (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c

ccdc88cbu8/+ (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210106-1
Synonyms: Not Available
Symbol: ccdc88c (AB) (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c (AB)

Ccdc88ctm1.1(KOMP)Mbp/Ccdc88ctm1.1(KOMP)Mbp [background:] C57BL/6N-Ccdc88ctm1.1(KOMP)Mbp/Ucd

(Mus musculus)
Model
Id: MGI:7551063
Synonyms: Not Available
Symbol: Ccdc88c/Ccdc88c [background:] C57BL/6N-Ccdc88c/Ucd (
Genes: Ccdc88c (Mmu)
Alleles: Ccdc88c (Mmu)
Name: Ccdc88c/Ccdc88c [background:] C57BL/6N-Ccdc88c/Ucd

ccdc88cbu8/bu8

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210923-1
Synonyms: Not Available
Symbol: ccdc88c (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c

ccdc88cbu8/bu8

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210923-4
Synonyms: Not Available
Symbol: ccdc88c (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c

Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp [background:] C57BL/6N-Ccdc88ctm1(KOMP)Mbp

(Mus musculus)
Model
Id: MGI:6460125
Synonyms: Not Available
Symbol: Ccdc88c/Ccdc88c [background:] C57BL/6N-Ccdc88c (Mmu)
Genes: Ccdc88c (Mmu)
Alleles: Ccdc88c (Mmu)
Name: Ccdc88c/Ccdc88c [background:] C57BL/6N-Ccdc88c

Ccdc88ctm1Mat/Ccdc88ctm1Mat [background:] Not Specified

(Mus musculus)
Model
Id: MGI:6470670
Synonyms: Not Available
Symbol: Ccdc88c/Ccdc88c [background:] Not Specified (Mmu)
Genes: Ccdc88c (Mmu)
Alleles: Ccdc88c (Mmu)
Name: Ccdc88c/Ccdc88c [background:] Not Specified

ccdc88cbu9/+ (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210106-2
Synonyms: Not Available
Symbol: ccdc88c (AB) (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c (AB)

ccdc88cbu9/bu9

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210923-2
Synonyms: Not Available
Symbol: ccdc88c (Dre)
Genes: ccdc88c (Dre)
Name: ccdc88c

grdn-1

(Caenorhabditis elegans)
Gene
Name: GiRDiN (mammalian actin-binding protein) homolog 1
Synonyms: Y51A2D.15, CELE_Y51A2D.15
Source: WB:WBGene00013082
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human CCDC88A (coiled-coil domain containing 88A) and CCDC88C (coiled-coil domain containing
Automated Gene Synopsis: Orthologous to several human genes including CCDC88A (coiled-coil domain containing 88A) and CCDC88C
Strict Orthology Symbols: ccdc88c

Girdin

(Drosophila melanogaster)
Gene
Name: Girdin
Synonyms: CG12734, mechanosensory A, mecA, girdin, dGirdin
Source: FB:FBgn0283724
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including CCDC88A (coiled-coil domain containing 88A) and CCDC88C
Strict Orthology Symbols: ccdc88c

spinocerebellar ataxia type 40

Disease
Source: DOID:0050986
Definition: An autosomal dominant cerebellar ataxia that is characterized by progressive gait abnormalities, dysarthria, tremor and hyporeflexia, has_material_basis_in mutation in the CCDC88C gene.
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)...ccdc88c (Dre)...ccdc88c (Xtr)

respiratory basal cell differentiation

Gene Ontology
Source: GO:1902691
Synonyms:
  • airway basal cell differentiation
Branch: biological process
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)

apical constriction

Gene Ontology
Source: GO:0003383
Synonyms: Not Available
Branch: biological process
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)...ccdc88c (Dre)

cytoskeleton-dependent intracellular transport

Gene Ontology
Source: GO:0030705
Synonyms: Not Available
Branch: biological process
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)...ccdc88c (Dre)

mucociliary clearance

Gene Ontology
Source: GO:0120197
Synonyms:
  • MCC
  • MCT
Branch: biological process
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)

bu8

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-210106-1
Genes: ccdc88c (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: ccdc88c (Dre)

bu9

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-210106-2
Genes: ccdc88c (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: ccdc88c (Dre)

dynein light intermediate chain binding

Gene Ontology
Source: GO:0051959
Synonyms: Not Available
Branch: molecular function
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)...ccdc88c (Dre)

Wnt signaling pathway, planar cell polarity pathway

Gene Ontology
Source: GO:0060071
Synonyms:
  • PCP pathway
  • Wnt receptor signaling pathway, planar cell polarity pathway
Branch: biological process
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)

G-protein alpha-subunit binding

Gene Ontology
Source: GO:0001965
Synonyms:
  • G-alpha protein subunit binding
Branch: molecular function
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)...ccdc88c (Dre)

non-canonical Wnt signaling pathway

Gene Ontology
Source: GO:0035567
Synonyms:
  • beta-catenin-independent Wnt receptor signaling pathway
  • non-canonical Wnt receptor signaling pathway
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

microtubule bundle formation

Gene Ontology
Source: GO:0001578
Synonyms:
  • microtubule bundling
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

hydrocephalus

Disease
Source: DOID:10908
Definition: A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...ccdc88c (Dre)...ccdc88c (Xtr)...Ccdc88c (Rno)

cytoplasmic microtubule organization

Gene Ontology
Source: GO:0031122
Synonyms:
  • cytoplasmic microtubule organisation
  • cytoplasmic microtubule organization and biogenesis
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...ccdc88c (Dre)...Ccdc88c (Rno)

negative regulation of microtubule depolymerization

Gene Ontology
Source: GO:0007026
Synonyms:
  • down regulation of microtubule depolymerization
  • down-regulation of microtubule depolymerization
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

apical junction complex

Gene Ontology
Source: GO:0043296
Synonyms:
  • apical cell junction complex
  • apical junction
Branch: cellular component
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

protein destabilization

Gene Ontology
Source: GO:0031648
Synonyms:
  • negative regulation of protein stability
  • protein destabilisation
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

cilium organization

Gene Ontology
Source: GO:0044782
Synonyms:
  • microtubule-based flagellum organization
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

frizzled binding

Gene Ontology
Source: GO:0005109
Synonyms:
  • frizzled ligand
  • frizzled-2 binding
Branch: molecular function
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

neural tube formation

Gene Ontology
Source: GO:0001841
Synonyms:
  • neural tube morphogenesis
  • neurulation
Branch: biological process
Genes: ccdc88c (Dre)

cilium movement

Gene Ontology
Source: GO:0003341
Synonyms:
  • ciliary motility
  • cilium beating
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

positive regulation of JNK cascade

Gene Ontology
Source: GO:0046330
Synonyms:
  • activation of JNK cascade
  • stimulation of JNK cascade
Branch: biological process
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

small GTPase-mediated signal transduction

Gene Ontology
Source: GO:0007264
Synonyms:
  • Ras family protein signal transduction
  • small GTPase mediated signal transduction
Branch: biological process
Genes: Ccdc88c (Mmu)...ccdc88c (Dre)...CCDC88C (Hsa)...Ccdc88c (Rno)

PDZ domain binding

Gene Ontology
Source: GO:0030165
Synonyms:
  • DHR-domain binding
  • GLGF-domain binding
Branch: molecular function
Genes: CCDC88C (Hsa)...Ccdc88c (Mmu)...Ccdc88c (Rno)

cell junction

Gene Ontology
Source: GO:0030054
Synonyms: Not Available
Branch: cellular component
Genes: Ccdc88c (Mmu)...ccdc88c (Dre)...CCDC88C (Hsa)...Ccdc88c (Rno)

negative regulation of canonical Wnt signaling pathway

Gene Ontology
Source: GO:0090090
Synonyms:
  • negative regulation of Wnt receptor signaling pathway through beta-catenin
  • negative regulation of canonical Wnt receptor signaling pathway
Branch: biological process
Genes: Ccdc88c (Mmu)...CCDC88C (Hsa)...Ccdc88c (Rno)

protein dimerization activity

Gene Ontology
Source: GO:0046983
Synonyms: Not Available
Branch: molecular function
Genes: Ccdc88c (Mmu)...Ccdc88c (Rno)...CCDC88C (Hsa)

microtubule binding

Gene Ontology
Source: GO:0008017
Synonyms:
  • microtubule severing activity
  • microtubule/chromatin interaction
Branch: molecular function
Genes: Ccdc88c (Mmu)...ccdc88c (Dre)...Ccdc88c (Rno)...CCDC88C (Hsa)

guanyl-nucleotide exchange factor activity

Gene Ontology
Source: GO:0005085
Synonyms:
  • ARF guanyl-nucleotide exchange factor activity
  • GDP-dissociation stimulator activity
Branch: molecular function
Genes: Ccdc88c (Mmu)...ccdc88c (Dre)...Ccdc88c (Rno)...CCDC88C (Hsa)