Version: 8.2.0Date: Wed Aug 27 2025
Category
coq-2
(Caenorhabditis elegans)Gene
Name: COenzyme Q (ubiquinone) biosynthesis 2
Synonyms: CELE_F57B9.4, F57B9.4
Source: WB:WBGene00000762
Biotype: protein coding gene
Symbol: coq-2 (Cel)
Symbol: coq-2
Gene Synopsis: coq-2 encodes a putative para-hydroxybenzoate-polyprenyl transferase(UbiA prenyltransferase), orthologous...to S. cerevisiae COQ2; COQ-2 isrequired for ubiquinone (coenzyme Q9) biosynthesis and for normallyshort...lifespan; coq-2 mutants have slowed pharyngeal pumping, andeventually arrest as paralysed larvae before...(RNAi) animalshave reduced levels of coenzyme Q9 and superoxide, and have abnormallylong lifespans; coq
Cross References: WB:coq-2...coq-2...coq-2
COQ2
(Homo sapiens)Gene
Name: coenzyme Q2, polyprenyltransferase
Synonyms: para-hydroxybenzoate--polyprenyltransferase, mitochondrial, PHB:PPT, 4-hydroxybenzoate polyprenyltransferase, mitochondrial, hCOQ2, COQ10D1, coenzyme Q2 homolog, prenyltransferase, coenzyme Q2 4-hydroxybenzoate polyprenyltransferase, FLJ26072, FLJ13014, para-hydroxybenzoate--polyprenyltransferase, MSA1, 4-HB polyprenyltransferase, para-hydroxybenzoate-polyprenyltransferase, mitochondrial, 4-hydroxybenzoate polyprenyltransferase, CL640, 4-hydroxybenzoate decaprenyltransferase, PHB:polyprenyltransferase, COQ2 homolog
Source: HGNC:25223
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
COQ2
(Saccharomyces cerevisiae)Gene
Name: COenzyme Q
Synonyms: YNR041C
Source: SGD:S000005324
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
Coq2
(Mus musculus)Gene
Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms: RIKEN cDNA 2310002F18 gene, 2310002F18Rik, RGD1306722, PHB:PPT
Source: MGI:1919133
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
Coq2
(Rattus norvegicus)Gene
Name: coenzyme Q2, polyprenyltransferase
Synonyms: similar to Hypothetical protein CL640 (predicted), RGD1306722, para-hydroxybenzoate--polyprenyltransferase, mitochondrial, PHB:PPT, LOC305167, 4-hydroxybenzoate polyprenyltransferase, mitochondrial, similar to Hypothetical protein CL640, coenzyme Q2 homolog, prenyltransferase, coenzyme Q2 4-hydroxybenzoate polyprenyltransferase, similar to 2310002F18Rik protein, MGC124824, 4-HB polyprenyltransferase, coenzyme Q2 homolog, prenyltransferase (yeast), RGD1306722_predicted, PHB:polyprenyltransferase
Source: RGD:1306722
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
Coq2
(Drosophila melanogaster)Gene
Name: Coenzyme Q2
Synonyms: sbo, COQ2, coq2, CG9613, small boy, coenzyme Q biosynthesis protein 2, cg9613, Coenzyme Q biosynthesis protein 2
Source: FB:FBgn0037574
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
coq2
(Danio rerio)Gene
Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms: zgc:162600
Source: ZFIN:ZDB-GENE-070410-84
Biotype: protein coding gene
Strict Orthology Symbols: coq-2
Gene Ontology
Source: GO:0008412
Synonyms:
- 4-HB polyprenyltransferase activity
- 4-hydroxybenzoate nonaprenyltransferase activity
Branch: molecular function
Genes: coq-2 (Cel)
coq2
(Xenopus tropicalis)Gene
Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms: coq2, coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Source: Xenbase:XB-GENE-967037
Biotype: gene
Strict Orthology Symbols: coq-2
Source: DOID:0070238
Definition: A primary coenzyme Q10 deficiency that has_material_basis_in an autosomal recessive mutation of the COQ2 gene on chromosome 4q21.22-q21.23.
Genes: coq-2 (Cel)
Source: DOID:0050730
Definition: A mitochondrial metabolism disease that is characterized by a deficiency of CoQ10 resulting from reduced biosynthesis.
Genes: coq-2 (Cel)
Source: GO:0016765
Synonyms:
- transferase activity, transferring alkyl or aryl groups, other than methyl groups
Branch: molecular function
Genes: coq-2 (Cel)
Gene Ontology
Source: GO:0006744
Synonyms:
- coenzyme Q biosynthesis
- coenzyme Q biosynthetic process
Branch: biological process
Genes: coq-2 (Cel)
Gene Ontology
Source: GO:0004659
Synonyms: Not Available
Branch: molecular function
Genes: coq-2 (Cel)
Gene Ontology
Source: GO:0008299
Synonyms:
- isoprenoid anabolism
- isoprenoid biosynthesis
Branch: biological process
Genes: coq-2 (Cel)
Disease
Source: DOID:1184
Definition: A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability.
Genes: coq-2 (Cel)
Gene Ontology
Source: GO:0031966
Synonyms: Not Available
Branch: cellular component
Genes: coq-2 (Cel)
Gene Ontology
Source: GO:0005743
Synonyms:
- inner mitochondrial membrane
- inner mitochondrion membrane
Branch: cellular component
Genes: coq-2 (Cel)
(WBcel235)III:6938054C>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938054C>G
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938054C>G
Gene Cross References: coq-2
(WBcel235)III:6937449C>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937449C>G
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937449C>G
Gene Cross References: coq-2
(WBcel235)III:6938537G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938537G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938537G>A
Gene Cross References: coq-2
(WBcel235)III:6936231G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936231G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936231G>A
Gene Cross References: coq-2
(WBcel235)III:6936864T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936864T>C
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936864T>C
Gene Cross References: coq-2
(WBcel235)III:6936903G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936903G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936903G>A
Gene Cross References: coq-2
(WBcel235)III:6937196C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937196C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937196C>T
Gene Cross References: coq-2
(WBcel235)III:6938570C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938570C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938570C>T
Gene Cross References: coq-2
(WBcel235)III:6937512C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937512C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937512C>T
Gene Cross References: coq-2
(WBcel235)III:6938050T>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938050T>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938050T>A
Gene Cross References: coq-2
(WBcel235)III:6938121G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938121G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938121G>A
Gene Cross References: coq-2
(WBcel235)III:6937916T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937916T>C
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937916T>C
Gene Cross References: coq-2
(WBcel235)III:6938828G>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938828G>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938828G>T
Gene Cross References: coq-2
(WBcel235)III:6938039G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938039G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938039G>A
Gene Cross References: coq-2
(WBcel235)III:6939036G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6939036G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6939036G>A
Gene Cross References: coq-2
(WBcel235)III:6936032C>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936032C>G
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936032C>G
Gene Cross References: coq-2
(WBcel235)III:6936504C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936504C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936504C>T
Gene Cross References: coq-2
(WBcel235)III:6936985C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6936985C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6936985C>T
Gene Cross References: coq-2
(WBcel235)III:6938052A>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938052A>C
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938052A>C
Gene Cross References: coq-2
(WBcel235)III:6938425T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938425T>C
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938425T>C
Gene Cross References: coq-2
(WBcel235)III:6939105C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6939105C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6939105C>T
Gene Cross References: coq-2
(WBcel235)III:6938097C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938097C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938097C>T
Gene Cross References: coq-2
(WBcel235)III:6938706G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938706G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938706G>A
Gene Cross References: coq-2
(WBcel235)III:6938850C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938850C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938850C>T
Gene Cross References: coq-2
(WBcel235)III:6937985T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937985T>C
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937985T>C
Gene Cross References: coq-2
(WBcel235)III:6938760T>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938760T>G
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938760T>G
Gene Cross References: coq-2
(WBcel235)III:6937695C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937695C>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937695C>T
Gene Cross References: coq-2
(WBcel235)III:6938941G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6938941G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6938941G>A
Gene Cross References: coq-2
(WBcel235)III:6937813A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937813A>T
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937813A>T
Gene Cross References: coq-2
(WBcel235)III:6937871G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003281.10:g.6937871G>A
Genes: coq-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)III:6937871G>A
Gene Cross References: coq-2