Version: 8.0.0Date: Tue Jan 28 2025
Category
grin1b
(Danio rerio)Gene
Name: glutamate receptor, ionotropic, N-methyl D-aspartate 1b
Synonyms: NMDAR1.2, si:rp71-1o1.1
Source: ZFIN:ZDB-GENE-051202-2
Biotype: protein coding gene
Symbol: grin1b (Dre)
Symbol: grin1b
grin1bs3020/s3020
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-231019-8
Synonyms: Not Available
Symbol: grin1b
Genes: grin1b (Dre)
Name: grin1b
grin1bsbu93/sbu93
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-230822-11
Synonyms: Not Available
Symbol: grin1b
Genes: grin1b (Dre)
Name: grin1b
grin1bsbu94/sbu94
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-210716-3
Synonyms: Not Available
Symbol: grin1b
Genes: grin1b (Dre)
Name: grin1b
grin1bs3020/+
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-231024-11
Synonyms: Not Available
Symbol: grin1b
Genes: grin1b (Dre)
Name: grin1b
GRIN1
(Homo sapiens)Gene
Name: glutamate ionotropic receptor NMDA type subunit 1
Synonyms: NDHMSR, glutamate [NMDA] receptor subunit zeta 1, glutamate receptor, ionotropic, N-methyl D-aspartate 1, GluN1, putative NMDtranscript(altAcc_e2), NR1, NMDAR1, glutamate [NMDA] receptor subunit zeta-1, glutamate receptor ionotropic, NMDA 1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, N-methyl-D-aspartate receptor channel, subunit zeta-1, NDHMSD, NMDA1, DEE101, MRD8
Source: HGNC:4584
Biotype: protein coding gene
Strict Orthology Symbols: grin1b
Nmdar1
(Drosophila melanogaster)Gene
Name: NMDA receptor 1
Synonyms: NRI, dsNR1, DrNR1, DmelNmdar1, nmr, Nmdar1, DNmdar, NMDA, dnmdar-I, nmdar1, DMNMDAR1, NMDA R1, dNR1, Nmdar, NMDA receptor I, nr1, NR1, NMDAR1, NmdaR1, DNMDAR-I, NMDA-R1, NMDAR, CG2902, NMDA receptor, NMdar1
Source: FB:FBgn0010399
Biotype: protein coding gene
Strict Orthology Symbols: grin1b
nmr-1
(Caenorhabditis elegans)Gene
Name: NMDA class glutamate Receptor 1
Synonyms: F07F6.6, F56D1.c, F56D1.b, CELE_F07F6.6
Source: WB:WBGene00003774
Biotype: protein coding gene
Strict Orthology Symbols: grin1b
Grin1
(Rattus norvegicus)Gene
Name: glutamate ionotropic receptor NMDA type subunit 1
Synonyms: neurotransmitter receptor, N-methyl-D-aspartate receptor subunit NR1, N-methyl-D-aspartate glutamate receptor, NMD-R1, glutamate receptor, ionotropic, N-methyl D-aspartate 1, N-methyl-D-aspartate receptor, GluN1, NR1, NMDAR1, NMDA R1 receptor C1 cassette, glutamate [NMDA] receptor subunit zeta-1, glutamate receptor ionotropic, NMDA 1
Source: RGD:2736
Biotype: protein coding gene
Strict Orthology Symbols: grin1b
Grin1
(Mus musculus)Gene
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1)
Synonyms: GluRzeta1, M100174, RIKEN Genomic Sciences Center, 174, Nmdar, GluN1, NR1, NMDAR1, Rgsc174
Source: MGI:95819
Biotype: protein coding gene
Strict Orthology Symbols: grin1b
grin1asbu90/sbu90; grin1bsbu94/sbu94
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-210716-4
Synonyms: Not Available
Genes: grin1b (Dre)
Name: grin1a; grin1b
Symbol: grin1a; grin1b
grin1
(Xenopus tropicalis)Gene
Name: glutamate ionotropic receptor NMDA type subunit 1
Synonyms: LOC108699855, grin1, nmda1, glutamate ionotropic receptor NMDA type subunit 1, nmdar1
Source: Xenbase:XB-GENE-494200
Biotype: gene
Strict Orthology Symbols: grin1b
s3020
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-220331-14
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: epilepsy
Variant Name: Not Available
Genes: grin1b (Dre)
la024950Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-120806-10883
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
zc69Tg + CRISPR1-grin1a + CRISPR1-grin1b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-190218-3
Synonyms: Not Available
Genes: grin1b (Dre)
Name: zc69Tg + CRISPR1-grin1a + CRISPR1-grin1b
WT + CRISPR1-grin1a + CRISPR1-grin1b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-190218-4
Synonyms: Not Available
Genes: grin1b (Dre)
Name: WT + CRISPR1-grin1a + CRISPR1-grin1b
Source: DOID:0070038
Definition: An autosomal dominant intellectual developmental disorder that has_material_basis_in an autosomal dominant mutation of the GRIN1 gene on chromosome 9q34.3.
Genes: grin1b (Dre)
Source: DOID:0070387
Definition: A developmental and epileptic encephalopathy characterized by early infantile epileptic encephalopathy and severe global developmental delay that has_material_basis_in homozygous mutation in the GRIN1 gene on chromosome 9q34.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0004972
Synonyms:
- N-methyl-D-aspartate selective glutamate receptor activity
- NMDA receptor
Branch: molecular function
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0022834
Synonyms: Not Available
Branch: molecular function
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0017146
Synonyms:
- N-methyl-D-aspartate selective glutamate receptor complex
- NMDA-selective glutamate receptor
Branch: cellular component
Genes: grin1b (Dre)
Disease
Source: DOID:3891
Definition: A placenta disease that is characterized by insufficient blood flow to the placenta during pregnancy.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0035235
Synonyms:
- ionotropic glutamate receptor signalling pathway
Branch: biological process
Genes: grin1b (Dre)
Disease
Source: DOID:11206
Definition: A substance abuse that involves the recurring use of opioid drugs despite negative consequences.
Genes: grin1b (Dre)
Disease
Source: DOID:1561
Definition: A disease of mental health that affects cognitive functions including memory processing, perception and problem solving.
Genes: grin1b (Dre)
Disease
Source: DOID:8725
Definition: A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0015276
Synonyms:
- ionotropic receptor activity
- ligand-gated ion channel activity
Branch: molecular function
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0042391
Synonyms: Not Available
Branch: biological process
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0070588
Synonyms:
- calcium ion membrane transport
- transmembrane calcium transport
Branch: biological process
Genes: grin1b (Dre)
Disease
Source: DOID:3526
Definition: A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0007268
Synonyms:
- neurotransmission
- signal transmission across a synapse
Branch: biological process
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0038023
Synonyms:
- receptor activity
- receptor activity involved in signal transduction
Branch: molecular function
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0005216
Synonyms:
- ion channel activity
Branch: molecular function
Genes: grin1b (Dre)
sa40455
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6672
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sbu95
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-201201-7
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: deletion
Molecular Consequence: frameshift_variant
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sbu94
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-201201-6
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: frameshift_variant
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sbu93
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-201201-5
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: deletion
Molecular Consequence: frameshift_variant
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sa10811
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130411-718
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sa18803
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-10388
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
sa6056
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-17961
Genes: grin1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: grin1b (Dre)
Disease
Source: DOID:1289
Definition: A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0045211
Synonyms:
- post-synaptic membrane
Branch: cellular component
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0016020
Synonyms:
- integral component of membrane
- integral to membrane
Branch: cellular component
Genes: grin1b (Dre)
Source: DOID:3525
Definition: Not Available
Genes: grin1b (Dre)
Disease
Source: DOID:0060041
Definition: A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior.
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0034220
Synonyms:
- ATP hydrolysis coupled ion transmembrane transport
- ion membrane transport
Branch: biological process
Genes: grin1b (Dre)
Gene Ontology
Source: GO:0006811
Synonyms:
- ion transport
Branch: biological process
Genes: grin1b (Dre)
Disease
Source: DOID:1826
Definition: A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions.
Genes: grin1b (Dre)