Version: 8.0.0Date: Tue Jan 28 2025
Category
Il1rap
(Mus musculus)Gene
Name: interleukin 1 receptor accessory protein
Synonyms: Il1racpb, IL-1RAcp, IL-1RAcP, AV239853, AI255955, RIKEN cDNA 6430709H04 gene, 6430709H04Rik, expressed sequence AI255955, IL-1R AcP, expressed sequence AV239853
Source: MGI:104975
Biotype: protein coding gene
Synonyms: IL-1RAcp...IL-1RAcP...IL-1RAcp...IL-1RAcP...IL-1RAcp...IL-1RAcP
IL1RAP
(Homo sapiens)Gene
Name: interleukin 1 receptor accessory protein
Synonyms: IL-1RAcP, IL-1 receptor accessory protein, FLJ37788, interleukin-1 receptor accessory protein, interleukin-1 receptor 3, IL1R3, interleukin-1 receptor accessory protein beta, IL-1R-3, IL-1R3, C3orf13
Source: HGNC:5995
Biotype: protein coding gene
Synonyms: IL-1RAcP...IL-1RAcP...IL-1RAcP
Il1rap
(Rattus norvegicus)Gene
Name: interleukin 1 receptor accessory protein
Synonyms: Il1racpb, IL-1RAcp, IL-1 receptor accessory protein, interleukin-1 receptor accessory protein, MGC114349
Source: RGD:2893
Biotype: protein coding gene
Synonyms: IL-1RAcp...IL-1RAcp...IL-1RAcp
Il1rapem1Smoc
(Mus musculus)Allele/Variant
Source: MGI:7290460
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1raptm1Amgn
(Mus musculus)Allele/Variant
Source: MGI:7750933
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem3Smoc
(Mus musculus)Allele/Variant
Source: MGI:7766233
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem2Smoc
(Mus musculus)Allele/Variant
Source: MGI:7626542
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1raptm1Roml
(Mus musculus)Allele/Variant
Source: MGI:1934017
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem2Adiuj
(Mus musculus)Allele/Variant
Source: MGI:6444733
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem1(IMPC)Ccpcz
(Mus musculus)Allele/Variant
Source: MGI:6442551
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1raptm3(IL1RAP)Smoc
(Mus musculus)Allele/Variant
Source: MGI:7626543
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem1Cya
(Mus musculus)Allele/Variant
Source: MGI:7584471
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem1Adiuj
(Mus musculus)Allele/Variant
Source: MGI:6164025
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7300753
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
Il1rapem3Gpt
(Mus musculus)Allele/Variant
Source: MGI:7300754
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: IL-1RAcp...IL-1RAcP
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by MGI
ID: ArrayExpress:E-GEOD-74695, GEO:GSE74695
Tags: WT vs. mutant, genotype
Summary: ST2 heterodimerizes with IL-1RAcp to form the receptor for IL-33, which is primarily associated with allergic inflammation by inducing Th2 responses. Recently, however, IL-33 was found to be expressed in the central nervous system and in retinal Muller cells which imply functions, as yet undescribed, beyond Th2 mediated inflammation. Muller cells support the health of the retina and photoreceptors and are also involved in inflammation in retinal degeneration. It is not known how IL-33/ST2 functions in this capacity. We recently found that ST2 ko mice are protected from CLE-induced photoreceptor loss, implying a detrimental effect of IL33/ST2 in CLE. We wish to perform microarray analysis using WT and ST2 KO mice in CLE model to better understand the mechanism by which IL-33/ST2 regulates retinal degeneration. CLE (Constant Light Exposure) is a model of retinal damage/degeneration in mice. Mice are exposed to bright light 24 hours a day for a period of time which damages retina photoreceptors. This damage is assessed by histology, optical coherence tomography (OCT), which measures retina thickness in vivo. In this experiment, the WT and ST2 KO mice (5 mice per genotype per time point) will be exposed to 1200-lux constant light for 0, 3, 10 days. The retinal RNA will be isolated and analyzed for differential gene expression by microarray.
(GRCh38)3:190620279G>A
(Homo sapiens)Allele/Variant
Source: rs1381460031
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190620279G>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190644319A>G
(Homo sapiens)Allele/Variant
Source: rs141817756
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190644319A>G
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604334C>T
(Homo sapiens)Allele/Variant
Source: rs1386571220
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604334C>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190627377G>T
(Homo sapiens)Allele/Variant
Source: rs756041268
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190627377G>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190627396C>T
(Homo sapiens)Allele/Variant
Source: rs142665925
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190627396C>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604401C>A
(Homo sapiens)Allele/Variant
Source: rs777978848
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604401C>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190656441A>G
(Homo sapiens)Allele/Variant
Source: rs74418158
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190656441A>G
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604213T>C
(Homo sapiens)Allele/Variant
Source: rs146492458
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604213T>C
Gene Synonyms: IL-1RAcP
(GRCh38)3:190648599G>C
(Homo sapiens)Allele/Variant
Source: rs145613403
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190648599G>C
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604284G>T
(Homo sapiens)Allele/Variant
Source: NC_000003.12:g.190604284G>T
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604284G>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190656425C>T
(Homo sapiens)Allele/Variant
Source: rs201781727
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190656425C>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190656169G>T
(Homo sapiens)Allele/Variant
Source: NC_000003.12:g.190656169G>T
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190656169G>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190656092G>A
(Homo sapiens)Allele/Variant
Source: rs1444026264
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190656092G>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190620339T>A
(Homo sapiens)Allele/Variant
Source: NC_000003.12:g.190620339T>A
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190620339T>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190556811C>G
(Homo sapiens)Allele/Variant
Source: rs207464173
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190556811C>G
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604288G>A
(Homo sapiens)Allele/Variant
Source: rs1577705910
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604288G>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190604281C>T
(Homo sapiens)Allele/Variant
Source: NC_000003.12:g.190604281C>T
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190604281C>T
Gene Synonyms: IL-1RAcP
(GRCh38)3:190620374G>A
(Homo sapiens)Allele/Variant
Source: rs372430202
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190620374G>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190629435T>C
(Homo sapiens)Allele/Variant
Source: rs1180685636
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190629435T>C
Gene Synonyms: IL-1RAcP
(GRCh38)3:190629458C>A
(Homo sapiens)Allele/Variant
Source: rs148996090
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190629458C>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190656067G>A
(Homo sapiens)Allele/Variant
Source: rs116127803
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190656067G>A
Gene Synonyms: IL-1RAcP
(GRCh38)3:190644248T>C
(Homo sapiens)Allele/Variant
Source: rs759387430
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190644248T>C
Gene Synonyms: IL-1RAcP
(GRCh38)3:190644353T>C
(Homo sapiens)Allele/Variant
Source: rs2108855383
Genes: IL1RAP (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)3:190644353T>C
Gene Synonyms: IL-1RAcP
(GRCm39)16:26539537C>A
(Mus musculus)Allele/Variant
Source: rs585372221
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26539537C>A
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26539801A>C
(Mus musculus)Allele/Variant
Source: rs1133060604
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26539801A>C
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26539492G>A
(Mus musculus)Allele/Variant
Source: rs582270336
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26539492G>A
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26540828T>C
(Mus musculus)Allele/Variant
Source: rs583638095
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26540828T>C
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26542195C>G
(Mus musculus)Allele/Variant
Source: rs246790855
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26542195C>G
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26544493G>A
(Mus musculus)Allele/Variant
Source: rs261206332
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26544493G>A
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26546930C>T
(Mus musculus)Allele/Variant
Source: rs236424732
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26546930C>T
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26547842G>A
(Mus musculus)Allele/Variant
Source: rs48206018
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26547842G>A
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26400727C>A
(Mus musculus)Allele/Variant
Source: rs250389952
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26400727C>A
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26400835T>C
(Mus musculus)Allele/Variant
Source: rs259934846
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26400835T>C
Gene Synonyms: IL-1RAcp...IL-1RAcP
(GRCm39)16:26532102A>G
(Mus musculus)Allele/Variant
Source: rs263007599
Genes: Il1rap (Mmu)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCm39)16:26532102A>G
Gene Synonyms: IL-1RAcp...IL-1RAcP