Version: 8.0.0
Date: Tue Jan 28 2025
56 results for kmt2cb

kmt2cb

(Danio rerio)
Gene
Name: lysine (K)-specific methyltransferase 2Cb
Synonyms: si:dkey-193e13.2, mll3b
Source: ZFIN:ZDB-GENE-070705-340
Biotype: protein coding gene
Symbol: kmt2cb (Dre)
Symbol: kmt2cb

kmt2cbuab319/+ (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-220315-19
Synonyms: Not Available
Symbol: kmt2cb (AB) (Dre)
Genes: kmt2cb (Dre)
Name: kmt2cb (AB)

KMT2C

(Homo sapiens)
Gene
Name: lysine methyltransferase 2C
Synonyms: histone-lysine N-methyltransferase, H3 lysine-4 specific, MLL3, histone-lysine N-methyltransferase MLL3, FLJ38309, FLJ12625, histone-lysine N-methyltransferase 2C, KLEFS2, ALR-like protein, myeloid/lymphoid or mixed-lineage leukemia protein 3, myeloid/lymphoid or mixed-lineage leukemia 3, MGC119852, lysine (K)-specific methyltransferase 2C, MGC119851, MGC119853, homologous to ALR protein, lysine N-methyltransferase 2C, DKFZp686C08112, KIAA1506, HALR
Source: HGNC:13726
Biotype: protein coding gene
Strict Orthology Symbols: kmt2cb

trr

(Drosophila melanogaster)
Gene
Name: trithorax-related
Synonyms: trithorax-related protein, Trithorax-related, trithorax related, TRR, Trr, CG3848, EG:63B12.3, dmll3/4, anon-2Bb, Trx-related
Source: FB:FBgn0023518
Biotype: protein coding gene
Strict Orthology Symbols: kmt2cb

set-16

(Caenorhabditis elegans)
Gene
Name: SET (trithorax/polycomb) domain containing 16
Synonyms: tag-350, CELE_T12D8.1, T12D8.1
Source: WB:WBGene00011729
Biotype: protein coding gene
Strict Orthology Symbols: kmt2cb

Kmt2c

(Mus musculus)
Gene
Name: lysine (K)-specific methyltransferase 2C
Synonyms: Mll3, mKIAA1506, RIKEN cDNA E330008K23 gene, E330008K23Rik, myeloid/lymphoid or mixed-lineage leukemia 3, HALR
Source: MGI:2444959
Biotype: protein coding gene
Strict Orthology Symbols: kmt2cb

Kmt2c

(Rattus norvegicus)
Gene
Name: lysine methyltransferase 2C
Synonyms: lysine (K)-specific methyltransferase 2C, LOC502710, similar to Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3), histone-lysine N-methyltransferase 2C, myeloid/lymphoid or mixed-lineage leukemia 3-like
Source: RGD:1587205
Biotype: protein coding gene
Strict Orthology Symbols: kmt2cb

la023445Tg

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-120806-12207
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

uab319

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-220315-25
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

WT + MO2-kmt2ca + MO2-kmt2cb

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-151029-11
Synonyms: Not Available
Genes: kmt2cb (Dre)
Name: WT + MO2-kmt2ca + MO2-kmt2cb

Kleefstra syndrome 2

Disease
Source: DOID:0080598
Definition: A Kleefstra syndrome that is characterized by delayed psychomotor development, variable intellectual disability, and mild dysmorphic features and has_material_basis_in heterozygous mutation in the KMT2C gene on chromosome 7q36.
Genes: kmt2cb (Dre)

histone H3K4 monomethyltransferase activity

Gene Ontology
Source: GO:0140945
Synonyms:
  • histone H3K4 monomethylase activity
  • histone H4-K4 methylation
Branch: molecular function
Genes: kmt2cb (Dre)

Klatskin's tumor

Disease
Source: DOID:4927
Definition: An intrahepatic cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts.
Genes: kmt2cb (Dre)

laryngeal carcinoma

Disease
Source: DOID:2600
Definition: A larynx cancer that has_material_basis_in epithelial cells.
Genes: kmt2cb (Dre)

MLL3/4 complex

Gene Ontology
Source: GO:0044666
Synonyms:
  • Trr/COMPASS-like complex
Branch: cellular component
Genes: kmt2cb (Dre)

adenoid cystic carcinoma

Disease
Source: DOID:0080202
Definition: An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.
Genes: kmt2cb (Dre)

histone H3K4 methyltransferase activity

Gene Ontology
Source: GO:0042800
Synonyms:
  • histone H3 lysine 4-specific methyltransferase activity
  • histone H3K4 methylase activity
Branch: molecular function
Genes: kmt2cb (Dre)

stomach carcinoma

Disease
Source: DOID:5517
Definition: A stomach cancer that is located_in the stomach.
Genes: kmt2cb (Dre)

squamous cell carcinoma

Disease
Source: DOID:1749
Definition: A carcinoma that derives_from squamous epithelial cells.
Genes: kmt2cb (Dre)

nasopharynx carcinoma

Disease
Source: DOID:9261
Definition: A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract.
Genes: kmt2cb (Dre)

methyltransferase activity

Gene Ontology
Source: GO:0008168
Synonyms:
  • methylase
Branch: molecular function
Genes: kmt2cb (Dre)

congenital heart disease

Disease
Source: DOID:1682
Definition: Not Available
Genes: kmt2cb (Dre)

methylation

Gene Ontology
Source: GO:0032259
Synonyms: Not Available
Branch: biological process
Genes: kmt2cb (Dre)

sa39785

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6150
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_region_variant, stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa39784

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6149
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa15663

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-130411-4215
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa5127

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-17642
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa25101

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-12262
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa19694

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-14857
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa39786

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6151
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa32861

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-1983
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa19695

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-14858
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa10821

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-130411-728
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa1802

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-10302
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa17423

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-13551
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa11689

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-130411-1495
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa25777

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-12639
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa38317

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-15826
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa6827

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-18551
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa17591

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-13693
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa5126

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-17641
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa38316

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-15825
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

sa38318

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-15827
Genes: kmt2cb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: kmt2cb (Dre)

esophagus squamous cell carcinoma

Disease
Source: DOID:3748
Definition: An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus.
Genes: kmt2cb (Dre)

regulation of DNA-templated transcription

Gene Ontology
Source: GO:0006355
Synonyms:
  • regulation of cellular transcription, DNA-dependent
  • regulation of gene-specific transcription
Branch: biological process
Genes: kmt2cb (Dre)

rheumatoid arthritis

Disease
Source: DOID:7148
Definition: An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint.
Genes: kmt2cb (Dre)

transcription coactivator activity

Gene Ontology
Source: GO:0003713
Synonyms:
  • RNA polymerase II transcription co-activator activity
  • RNA polymerase II transcription coactivator activity
Branch: molecular function
Genes: kmt2cb (Dre)

lung adenocarcinoma

Disease
Source: DOID:3910
Definition: A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.
Genes: kmt2cb (Dre)

chromatin organization

Gene Ontology
Source: GO:0006325
Synonyms:
  • DNA replication-independent chromatin assembly
  • DNA replication-independent chromatin organization
Branch: biological process
Genes: kmt2cb (Dre)

stomach cancer

Disease
Source: DOID:10534
Definition: A gastrointestinal system cancer that is located_in the stomach.
Genes: kmt2cb (Dre)