Version: 8.0.0Date: Tue Jan 28 2025
Category
Map3k15
(Mus musculus)Gene
Name: mitogen-activated protein kinase kinase kinase 15
Synonyms: AABR07038029.1, BC031147, RGD1560603, cDNA sequence BC031147
Source: MGI:2448588
Biotype: protein coding gene
Symbol: Map3k15 (Mmu)
Symbol: Map3k15
Automated Gene Synopsis: Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15).
Strict Orthology Symbols: map3k15
Alleles: Map3k15
MAP3K15
(Homo sapiens)Gene
Name: mitogen-activated protein kinase kinase kinase 15
Synonyms: MEK kinase 15, MAPK/ERK kinase kinase 15, ASK3, bA723P2.3, FLJ16518, MEKK 15, apoptosis signal-regulating kinase 3
Source: HGNC:31689
Biotype: protein coding gene
Symbol: MAP3K15 (Hsa)
Symbol: MAP3K15
Strict Orthology Symbols: map3k15
map3k15
(Danio rerio)Gene
Name: mitogen-activated protein kinase kinase kinase 15
Synonyms: si:dkey-108d10.2
Source: ZFIN:ZDB-GENE-091204-246
Biotype: protein coding gene
Symbol: map3k15 (Dre)
Symbol: map3k15
Automated Gene Synopsis: Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15).
Strict Orthology Symbols: Map3k15...MAP3K15
Map3k15
(Rattus norvegicus)Gene
Name: mitogen-activated protein kinase kinase kinase 15
Synonyms: AABR07038029.1, LOC501558, similar to mitogen-activated protein kinase kinase kinase 15, RGD1560603
Source: RGD:1560603
Biotype: protein coding gene
Symbol: Map3k15 (Rno)
Symbol: Map3k15
Gene Synopsis: Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15); INTERACTS WITH 17beta-estradiol
Automated Gene Synopsis: Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15).
Strict Orthology Symbols: map3k15
Map3k15tm1Hijo
(Mus musculus)Allele/Variant
Source: MGI:5644160
Genes: Map3k15 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Map3k15
Genes: Map3k15 (Mmu)
Symbol: Map3k15tm1Hijo
Map3k15tm1(cre)Stl
(Mus musculus)Allele/Variant
Source: MGI:6117443
Genes: Map3k15 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Map3k15
Genes: Map3k15 (Mmu)
Symbol: Map3k15tm1(cre)Stl
Construct Regulatory Region: Map3k15 (Mmu)
Constructs: Map3k15< construct
Map3k15em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7301977
Genes: Map3k15 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Map3k15
Genes: Map3k15 (Mmu)
Symbol: Map3k15em1Gpt
Map3k15tm1a(KOMP)Wtsi
(Mus musculus)Allele/Variant
Source: MGI:4364582
Genes: Map3k15 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Map3k15
Genes: Map3k15 (Mmu)
Symbol: Map3k15tm1a(KOMP)Wtsi
Map3k15tm1Hijo/Y [background:] involves: C57BL/6 * ICR
(Mus musculus)Model
Id: MGI:5688978
Synonyms: Not Available
Symbol: Map3k15/Y [background:] involves: C57BL/6 * ICR (Mmu)
Genes: Map3k15 (Mmu)
Alleles: Map3k15
Name: Map3k15/Y [background:] involves: C57BL/6 * ICR
nsy-1
(Caenorhabditis elegans)Gene
Name: Neuronal SYmmetry 1
Synonyms: ask-1, F59A6.1, CELE_F59A6.1, esp-8, srf-6, xts-1
Source: WB:WBGene00003822
Biotype: protein coding gene
Strict Orthology Symbols: map3k15
Ask1
(Drosophila melanogaster)Gene
Name: Apoptotic signal-regulating kinase 1
Synonyms: DPk92B/ASK1, DASK1, Apoptotic signal-regulating kinase 1, D-ASK, Protein kinase at 92B, dASK1, ASK1, Ask1, DASK, CG4720, MEKK5/ASK1, ask1, pk92B, Pk92B, Ask, dASK, dAsk1
Source: FB:FBgn0014006
Biotype: protein coding gene
Strict Orthology Symbols: map3k15
Gene Ontology
Source: GO:0038066
Synonyms:
- MAPK14 cascade
- osmosensory signaling MAPK cascade
Branch: biological process
Genes: map3k15 (Dre)...Map3k15 (Mmu)...Map3k15 (Rno)...MAP3K15 (Hsa)
Gene Ontology
Source: GO:0004709
Synonyms:
- ATP:protein phosphotransferase (MAPKKKK-activated) activity
- MAP3K
Branch: molecular function
Genes: Map3k15 (Rno)...MAP3K15 (Hsa)...map3k15 (Dre)...Map3k15 (Mmu)
Gene Ontology
Source: GO:0004706
Synonyms:
- JNK kinase kinase activity
- JNKKK
Branch: molecular function
Genes: map3k15 (Dre)...Map3k15 (Mmu)...MAP3K15 (Hsa)
Disease
Source: DOID:670
Definition: A substance abuse that involves the recurring use of amphetamines despite negative consequences.
Genes: Map3k15 (Rno)...MAP3K15 (Hsa)...map3k15 (Dre)...Map3k15 (Mmu)
Gene Ontology
Source: GO:0007254
Synonyms:
- JNK1 cascade
- JNK2 cascade
Branch: biological process
Genes: MAP3K15 (Hsa)...Map3k15 (Rno)...map3k15 (Dre)...Map3k15 (Mmu)
Gene Ontology
Source: GO:0000165
Synonyms:
- ERK/MAPK cascade
- MAP kinase cascade
Branch: biological process
Genes: MAP3K15 (Hsa)...Map3k15 (Rno)...Map3k15 (Mmu)...map3k15 (Dre)
Gene Ontology
Source: GO:0106310
Synonyms:
- protein-serine kinase activity
Branch: molecular function
Genes: Map3k15 (Mmu)...MAP3K15 (Hsa)
Gene Ontology
Source: GO:0004672
Synonyms:
- protamine kinase activity
Branch: molecular function
Genes: map3k15 (Dre)...MAP3K15 (Hsa)
Gene Ontology
Source: GO:0004674
Synonyms:
- protein serine kinase activity
- protein serine-threonine kinase activity
Branch: molecular function
Genes: map3k15 (Dre)...MAP3K15 (Hsa)
Gene Ontology
Source: GO:0000166
Synonyms: Not Available
Branch: molecular function
Genes: map3k15 (Dre)
sa24513
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-131217-17797
Genes: map3k15 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_acceptor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: map3k15 (Dre)
sa13317
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130411-2954
Genes: map3k15 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: map3k15 (Dre)
sa44153
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-9554
Genes: map3k15 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: map3k15 (Dre)
Gene Ontology
Source: GO:0005524
Synonyms:
- Mg-ATP binding
- MgATP binding
Branch: molecular function
Genes: map3k15 (Dre)...MAP3K15 (Hsa)...Map3k15 (Rno)...Map3k15 (Mmu)
sa44154
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-9555
Genes: map3k15 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: map3k15 (Dre)
sa37904
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-15697
Genes: map3k15 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: map3k15 (Dre)
Gene Ontology
Source: GO:0016310
Synonyms: Not Available
Branch: biological process
Genes: map3k15 (Dre)
(GRCh38)X:19373679G>A
(Homo sapiens)Allele/Variant
Source: rs139451743
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19373679G>A
(GRCh38)X:19374487G>T
(Homo sapiens)Allele/Variant
Source: rs267606415
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19374487G>T
(GRCh38)X:19431471T>C
(Homo sapiens)Allele/Variant
Source: rs376514232
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19431471T>C
(GRCh38)X:19464275C>G
(Homo sapiens)Allele/Variant
Source: rs200022856
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19464275C>G
(GRCh38)X:19464380G>A
(Homo sapiens)Allele/Variant
Source: rs5955788
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19464380G>A
(GRCh38)X:19515011C>G
(Homo sapiens)Allele/Variant
Source: rs754707908
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19515011C>G
(GRCh38)X:19407271A>C
(Homo sapiens)Allele/Variant
Source: rs375521492
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19407271A>C
(GRCh38)X:19415154T>C
(Homo sapiens)Allele/Variant
Source: NC_000023.11:g.19415154T>C
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19415154T>C
(GRCh38)X:19415188C>T
(Homo sapiens)Allele/Variant
Source: rs56125741
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19415188C>T
(GRCh38)X:19425567G>A
(Homo sapiens)Allele/Variant
Source: rs1323309433
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19425567G>A
(GRCh38)X:19409962G>A
(Homo sapiens)Allele/Variant
Source: rs369231619
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19409962G>A
(GRCh38)X:19464336C>T
(Homo sapiens)Allele/Variant
Source: rs55916006
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19464336C>T
(GRCh38)X:19515045C>A
(Homo sapiens)Allele/Variant
Source: rs1258691915
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19515045C>A
(GRCh38)X:19392342C>A
(Homo sapiens)Allele/Variant
Source: rs150236554
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, splice_donor_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19392342C>A
(GRCh38)X:19431553G>C
(Homo sapiens)Allele/Variant
Source: rs1424056144
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19431553G>C
(GRCh38)X:19459989A>C
(Homo sapiens)Allele/Variant
Source: rs952918430
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19459989A>C
(GRCh38)X:19460082G>A
(Homo sapiens)Allele/Variant
Source: rs755751423
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19460082G>A
(GRCh38)X:19464234T>G
(Homo sapiens)Allele/Variant
Source: rs765136099
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19464234T>G
(GRCh38)X:19464358C>T
(Homo sapiens)Allele/Variant
Source: rs5909299
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19464358C>T
(GRCh38)X:19373601G>A
(Homo sapiens)Allele/Variant
Source: rs193102767
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19373601G>A
(GRCh38)X:19373678C>T
(Homo sapiens)Allele/Variant
Source: rs377079007
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19373678C>T
(GRCh38)X:19488913T>C
(Homo sapiens)Allele/Variant
Source: rs931290479
Genes: MAP3K15 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)X:19488913T>C