Version: 8.0.0Date: Tue Jan 28 2025
Category
Pacs2
(Rattus norvegicus)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: LOC691631, hypothetical protein LOC691631
Source: RGD:1597262
Biotype: protein coding gene
Symbol: Pacs2 (Rno)
Symbol: Pacs2
Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2); INTERACTS WITH amphetamine
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
pacs2
(Danio rerio)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: Not Available
Source: ZFIN:ZDB-GENE-081218-1
Biotype: protein coding gene
Symbol: pacs2 (Dre)
Symbol: pacs2
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
Pacs2
(Mus musculus)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: phosphofurin acidic cluster sorting protein 1-like, expressed sequence AW489976, mKIAA0602, expressed sequence AW208651, Pacs1l, AW208651, RIKEN cDNA 6720425G15 gene, 6720425G15Rik, AW489976
Source: MGI:1924399
Biotype: protein coding gene
Symbol: Pacs2 (Mmu)
Symbol: Pacs2
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
Alleles: Pacs2
PACS2
(Homo sapiens)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: PACS-2, phosphofurin acidic cluster sorting protein 1-like, KIAA0602, FLJ25488, EIEE66, PACS1-like protein, DEE66, PACS1L
Source: HGNC:23794
Biotype: protein coding gene
Symbol: PACS2 (Hsa)
Symbol: PACS2
Strict Orthology Symbols: pacs2
pacs2
(Xenopus tropicalis)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: phosphofurin acidic cluster sorting protein 2, pacs2
Source: Xenbase:XB-GENE-5903639
Biotype: gene
Symbol: pacs2
Symbol: pacs2 (Xtr)
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Synonyms: pacs2...pacs2...pacs2
Strict Orthology Symbols: pacs2
pacs2.S
(Xenopus laevis)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: phosphofurin acidic cluster sorting protein 2, pacs2.S
Source: Xenbase:XB-GENE-17337350
Biotype: gene
Symbol: pacs2.S (Xla)
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
Symbol: pacs2.S
pacs2.L
(Xenopus laevis)Gene
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: phosphofurin acidic cluster sorting protein 2, pacs2.L
Source: Xenbase:XB-GENE-5903703
Biotype: gene
Symbol: pacs2.L (Xla)
Automated Gene Synopsis: Orthologous to human PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
Symbol: pacs2.L
Pacs2em2Smoc
(Mus musculus)Allele/Variant
Source: MGI:7316495
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2em2Smoc
Pacs2em2Gpt
(Mus musculus)Allele/Variant
Source: MGI:7303824
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2em2Gpt
Pacs2em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7303823
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2em1Gpt
Pacs2em1Huan
(Mus musculus)Allele/Variant
Source: MGI:7571617
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2em1Huan
Pacs2tm1c(EUCOMM)Hmgu
(Mus musculus)Allele/Variant
Source: MGI:7657949
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2tm1c(EUCOMM)Hmgu
Pacs2em1Smoc
(Mus musculus)Allele/Variant
Source: MGI:7291512
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2em1Smoc
Pacs2Gt(OST426086)Lex
(Mus musculus)Allele/Variant
Source: MGI:4313108
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2Gt(OST426086)Lex
Pacs2tm1a(EUCOMM)Hmgu
(Mus musculus)Allele/Variant
Source: MGI:4435377
Genes: Pacs2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Pacs2
Genes: Pacs2 (Mmu)
Symbol: Pacs2tm1a(EUCOMM)Hmgu
Pacs2Gt(OST426086)Lex/Pacs2Gt(OST426086)Lex [background:] involves: 129S5/SvEvBrd * NIH Black Swiss
(Mus musculus)Model
Id: MGI:4410463
Synonyms: Not Available
Symbol: Pacs2/Pacs2 [background:] involves: 129S5/SvEvBrd * NIH Black Swiss
Genes: Pacs2 (Mmu)
Alleles: Pacs2
Name: Pacs2/Pacs2 [background:] involves: 129S5/SvEvBrd * NIH Black Swiss
Pacs2tm1a(EUCOMM)Hmgu/Pacs2tm1a(EUCOMM)Hmgu [background:] C57BL/6N-Pacs2tm1a(EUCOMM)Hmgu/Ics
(Mus musculus)Model
Id: MGI:5782154
Synonyms: Not Available
Symbol: Pacs2/Pacs2 [background:] C57BL/6N-Pacs2/Ics (
Genes: Pacs2 (Mmu)
Alleles: Pacs2
Name: Pacs2/Pacs2 [background:] C57BL/6N-Pacs2/Ics
Pacs
(Drosophila melanogaster)Gene
Name: Phosphofurin acidic cluster sorting protein
Synonyms: KrT95D, Krueppel target at 95D, CG5405
Source: FB:FBgn0020647
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including PACS2 (phosphofurin acidic cluster sorting protein 2).
Strict Orthology Symbols: pacs2
pacs-1
(Caenorhabditis elegans)Gene
Name: Phosphofurin Acidic Cluster Sorting protein homolog 1
Synonyms: CELE_T18H9.7, tag-232, T18H9.7
Source: WB:WBGene00044077
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human PACS1 (phosphofurin acidic cluster sorting protein 1) and PACS2 (phosphofurin
Automated Gene Synopsis: Orthologous to human PACS1 (phosphofurin acidic cluster sorting protein 1) and PACS2 (phosphofurin acidic
Strict Orthology Symbols: pacs2
Source: DOID:0080446
Definition: A developmental and epileptic encephalopathy characterized by onset in the first days or weeks of life of seizures, global developmental delay with hypotonia, behavioral abnormalities, and dysmorphic features or ophthalmologic defects that has_material_basis_in heterozygous mutation in the PACS2 gene on chromosome 14q32.
Genes: pacs2.L (Xla)...Pacs2 (Rno)...Pacs2 (Mmu)...pacs2 (Xtr)...pacs2 (Dre)
Source: GO:1990456
Synonyms:
- mitochondrion-ER attachment
- mitochondrion-ER membrane tethering
Branch: biological process
Genes: Pacs2 (Rno)...Pacs2 (Mmu)...PACS2 (Hsa)
WT + MO1-pacs2
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-25513
Synonyms: Not Available
Genes: pacs2 (Dre)
Name: WT + MO1-pacs2
WT + MO1-pacs1a + MO1-pacs2
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-1905
Synonyms: Not Available
Genes: pacs2 (Dre)
Name: WT + MO1-pacs1a + MO1-pacs2
la027450Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-130129-2257
Genes: pacs2 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: pacs2 (Dre)
Gene Ontology
Source: GO:0034497
Synonyms:
- protein localisation to phagophore assembly site
- protein localization to PAS
Branch: biological process
Genes: Pacs2 (Rno)...Pacs2 (Mmu)...PACS2 (Hsa)
Gene Ontology
Source: GO:0032469
Synonyms:
- ER calcium ion concentration regulation
- ER calcium ion homeostasis
Branch: biological process
Genes: Pacs2 (Rno)...Pacs2 (Mmu)...PACS2 (Hsa)
Hsap\PACS2UAS.cBa
(Drosophila melanogaster)Allele/Variant
Source: FB:FBal0366419
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\PACS2
Construct Expressed Component: PACS2 (Hsa)
Igs2em1(Myh6-Pacs2)Huan
(Mus musculus)Allele/Variant
Source: MGI:7571618
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Igs2Pacs2)Huan>
Construct Expressed Component: Pacs2 (Mmu)
Gene Ontology
Source: GO:0044325
Synonyms:
- ion channel binding
Branch: molecular function
Genes: PACS2 (Hsa)...Pacs2 (Mmu)...pacs2 (Dre)...Pacs2 (Rno)
Gene Ontology
Source: GO:0000045
Synonyms:
- PAS formation
- autophagic vacuole assembly
Branch: biological process
Genes: PACS2 (Hsa)...Pacs2 (Mmu)...Pacs2 (Rno)
Gene Ontology
Source: GO:0072659
Synonyms:
- protein localisation in plasma membrane
- protein localization in plasma membrane
Branch: biological process
Genes: PACS2 (Hsa)...Pacs2 (Mmu)...pacs2 (Dre)...Pacs2 (Rno)
Gene Ontology
Source: GO:0006915
Synonyms:
- activation of apoptosis
- apoptosis
Branch: biological process
Genes: PACS2 (Hsa)...Pacs2 (Mmu)
Gene Ontology
Source: GO:0005739
Synonyms:
- mitochondria
Branch: cellular component
Genes: PACS2 (Hsa)...Pacs2 (Mmu)...Pacs2 (Rno)
sa35555
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-3967
Genes: pacs2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: pacs2 (Dre)
sa31948
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-14442
Genes: pacs2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_acceptor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: pacs2 (Dre)
(GRCh38)14:105348509C>T
(Homo sapiens)Allele/Variant
Source: rs782182727
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105348509C>T
(GRCh38)14:105348571C>G
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.105348571C>G
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105348571C>G
(GRCh38)14:105355132C>T
(Homo sapiens)Allele/Variant
Source: rs1003006997
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105355132C>T
(GRCh38)14:105355156G>A
(Homo sapiens)Allele/Variant
Source: rs149722060
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105355156G>A
(GRCh38)14:105369908C>T
(Homo sapiens)Allele/Variant
Source: rs587658173
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105369908C>T
(GRCh38)14:105369911C>G
(Homo sapiens)Allele/Variant
Source: rs371774004
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105369911C>G
(GRCh38)14:105355342C>T
(Homo sapiens)Allele/Variant
Source: rs73359061
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105355342C>T
(GRCh38)14:105368110C>G
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.105368110C>G
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105368110C>G
(GRCh38)14:105367279G>T
(Homo sapiens)Allele/Variant
Source: rs1555408179
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105367279G>T
(GRCh38)14:105368112G>C
(Homo sapiens)Allele/Variant
Source: rs1555408401
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105368112G>C
(GRCh38)14:105391643A>T
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.105391643A>T
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105391643A>T
(GRCh38)14:105391690G>A
(Homo sapiens)Allele/Variant
Source: rs782122419
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105391690G>A
(GRCh38)14:105391708G>A
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.105391708G>A
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105391708G>A
(GRCh38)14:105392750G>A
(Homo sapiens)Allele/Variant
Source: rs146590511
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105392750G>A
(GRCh38)14:105392780G>C
(Homo sapiens)Allele/Variant
Source: rs1555415282
Genes: PACS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:105392780G>C