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Category

11,933 results for plcl1

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plcl1

(Danio rerio)

Gene

Name: phospholipase C like 1

Synonyms: si:dkey-15m21.1

Source: ZFIN:ZDB-GENE-090313-194

Biotype: protein coding gene

Symbol: plcl1 (Dre)

Symbol: plcl1

Automated Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).

Strict Orthology Symbols: plcl1

Plcl1

(Rattus norvegicus)

Gene

Name: phospholipase C-like 1

Synonyms: phospholipase C-related but catalytically inactive protein, 130kDa-Ins(1,4,5)P3 binding protein, PRIP1, inactive phospholipase C-like protein 1, PLC-L1, p130, LOC84587

Source: RGD:708420

Biotype: protein coding gene

Symbol: Plcl1 (Rno)

Symbol: Plcl1

Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)); INTERACTS WITH 17alpha-ethynylestradiol

Automated Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).

Strict Orthology Symbols: plcl1

Allele/Variant (1145)

PLCL1

(Homo sapiens)

Gene

Name: phospholipase C like 1 (inactive)

Synonyms: PLCL, MGC126580, phospholipase C-related but catalytically inactive protein, PLDL1, PPP1R127, MGC138190, PRIP, 130kda-ins(1,4,5)p3 binding protein, phospholipase C, epsilon, phospholipase C like 1, phospholipase C related, but catalytically inactive protein, inactive phospholipase C-like protein 1, PLC-L1, PLCE, phospholipase C-like 1, phospholipase C-deleted in lung carcinoma

Source: HGNC:9063

Biotype: protein coding gene

Symbol: PLCL1 (Hsa)

Symbol: PLCL1

Strict Orthology Symbols: plcl1

Allele/Variant (65)

Plcl1

(Mus musculus)

Gene

Name: phospholipase C-like 1

Synonyms: PRIP-1, RIKEN cDNA C230017K02 gene, PLC-L, C230017K02Rik

Source: MGI:3036262

Biotype: protein coding gene

Symbol: Plcl1 (Mmu)

Symbol: Plcl1

Automated Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).

Strict Orthology Symbols: plcl1

Alleles: Plcl1 (Mmu)...Plcl1 (Mmu)...Plcl1 (Mmu)...Plcl1 (Mmu)

plcl1

(Xenopus tropicalis)

Gene

Name: phospholipase C like 1 (inactive)

Synonyms: plcl1, LOC108703054, phospholipase C like 1 (inactive), plcl, pldl1, plce, prip, LOC108701442

Source: Xenbase:XB-GENE-6468167

Biotype: gene

Symbol: plcl1

Symbol: plcl1 (Xtr)

Automated Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)).

Synonyms: plcl1...plcl1...plcl1

Strict Orthology Symbols: plcl1

Plcl1^tm2.1Matk

(Mus musculus)

Allele/Variant

Source: MGI:5607952

Genes: Plcl1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Symbol: Plcl1^tm2.1Matk

Plcl1^tm1Mh

(Mus musculus)

Allele/Variant

Source: MGI:3526123

Genes: Plcl1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Symbol: Plcl1^tm1Mh

Plcl1^em10Gpt

(Mus musculus)

Allele/Variant

Source: MGI:7304352

Genes: Plcl1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Symbol: Plcl1^em10Gpt

Gene (1)

Plcl1^tm1.1Matk

(Mus musculus)

Allele/Variant

Source: MGI:5607951

Genes: Plcl1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Symbol: Plcl1^tm1.1Matk

Plcl1^tm1Mh/Plcl1^tm1Mh [background:] involves: C57BL/6

(Mus musculus)

Model

Id: MGI:3526259

Synonyms: Not Available

Symbol: Plcl1/Plcl1 [background:] involves: C57BL/6 (Mmu)

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Plcl1/Plcl1 [background:] involves: C57BL/6

Gene (1)

Plcl1^tm1.1Matk/Plcl1^tm1.1Matk [background:] FVB.Cg-Plcl1^tm1.1Matk

(Mus musculus)

Model

Id: MGI:5607953

Synonyms: Not Available

Symbol: Plcl1/Plcl1 [background:] FVB.Cg-Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Plcl1/Plcl1 [background:] FVB.Cg-Plcl1

Gene (1)

Plcl1^tm1Mh/Plcl1^tm1Mh [background:] involves: 129/Sv * C57BL/6

(Mus musculus)

Model

Id: MGI:3526813

Synonyms: Not Available

Symbol: Plcl1/Plcl1 [background:] involves: 129/Sv * C57BL/6 (Mmu)

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Plcl1/Plcl1 [background:] involves: 129/Sv * C57BL/6

Gene (1)

plcl1^a323/a323

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-200507-33

Synonyms: Not Available

Symbol: plcl1 (Dre)

Genes: plcl1 (Dre)

Name: plcl1

Gene (1)

Plcl1^tm2.1Matk/Plcl1^tm2.1Matk [background:] FVB.Cg-Plcl1^tm2.1Matk

(Mus musculus)

Model

Id: MGI:5607956

Synonyms: Not Available

Symbol: Plcl1/Plcl1 [background:] FVB.Cg-Plcl1 (Mmu)

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Plcl1/Plcl1 [background:] FVB.Cg-Plcl1

Gene (1)

Plcl1^tm1.1Matk/Plcl1^tm1.1Matk [background:] involves: C57BL/6 * FVB

(Mus musculus)

Model

Id: MGI:5607954

Synonyms: Not Available

Symbol: Plcl1/Plcl1 [background:] involves: C57BL/6 * FVB (Mmu)

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Plcl1/Plcl1 [background:] involves: C57BL/6 * FVB

Gene (1)

pll-1

(Caenorhabditis elegans)

Gene

Name: PhosphoLipase C Like 1

Synonyms: K10F12.3, CELE_K10F12.3

Source: WB:WBGene00004045

Biotype: protein coding gene

Gene Synopsis: Is an ortholog of human PLCL1 (phospholipase C like 1 (inactive)) and PLCL2 (phospholipase C like 2).

Automated Gene Synopsis: Orthologous to human PLCL1 (phospholipase C like 1 (inactive)) and PLCL2 (phospholipase C like 2).

Strict Orthology Symbols: plcl1

Allele/Variant (189)

PLC1

(Saccharomyces cerevisiae)

Gene

Name: PhosphoLipase C

Synonyms: YPL268W

Source: SGD:S000006189

Biotype: protein coding gene

Strict Orthology Symbols: plcl1

Kras^tm4Tyj/Kras⁺ Plcl1^tm1.1Matk/Plcl1^tm1.1Matk [background:] involves: 129S4/SvJae * C57BL/6

(Mus musculus)

Model

Id: MGI:5607955

Synonyms: Not Available

Genes: Plcl1 (Mmu)

Alleles: Plcl1 (Mmu)

Name: Kras/Kras<+> Plcl1/Plcl1 [background:] involves: 129S4/SvJae * C57BL/6

Symbol: Kras/Kras<+> Plcl1/Plcl1 [background:] involves: 129S4/SvJae * C57BL/6

Gene (2)

la026917Tg

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-120806-11068

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

Gene (1)

a323

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-200217-16

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

regulation of synaptic transmission, GABAergic

Gene Ontology

Source: GO:0032228

Synonyms: Not Available

Branch: biological process

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)...PLCL1 (Hsa)

Genes Annotated with this GO Term (152)

positive regulation of receptor binding

Gene Ontology

Source: GO:1900122

Synonyms:

activation of receptor binding
up regulation of receptor binding

Branch: biological process

Genes: Plcl1 (Mmu)

Genes Annotated with this GO Term (7)

phosphatidylinositol phospholipase C activity

Gene Ontology

Source: GO:0004435

Synonyms:

1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity

Branch: molecular function

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)...PLCL1 (Hsa)

Genes Annotated with this GO Term (94)

GABA receptor binding

Gene Ontology

Source: GO:0050811

Synonyms:

4-aminobutanoate receptor binding
4-aminobutyrate receptor binding

Branch: molecular function

Genes: Plcl1 (Mmu)...Plcl1 (Rno)...PLCL1 (Hsa)

Genes Annotated with this GO Term (68)

gamma-aminobutyric acid signaling pathway

Gene Ontology

Source: GO:0007214

Synonyms:

4-aminobutanoate signaling pathway
4-aminobutanoate signalling pathway

Branch: biological process

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)...PLCL1 (Hsa)

Genes Annotated with this GO Term (127)

phosphatidylinositol-mediated signaling

Gene Ontology

Source: GO:0048015

Synonyms:

inositol phospholipid-mediated signaling
phosphatidylinositol-mediated signal transduction

Branch: biological process

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)

Genes Annotated with this GO Term (110)

phospholipase C activity

Gene Ontology

Source: GO:0004629

Synonyms:

phosphatidase C

Branch: molecular function

Genes: PLCL1 (Hsa)

Genes Annotated with this GO Term (100)

phosphatidylinositol metabolic process

Gene Ontology

Source: GO:0046488

Synonyms:

PtdIns metabolic process
PtdIns metabolism

Branch: biological process

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)

Genes Annotated with this GO Term (778)

negative regulation of cold-induced thermogenesis

Gene Ontology

Source: GO:0120163

Synonyms:

negative regulation of CIT

Branch: biological process

Genes: Plcl1 (Mmu)...Plcl1 (Rno)...PLCL1 (Hsa)

Genes Annotated with this GO Term (144)

release of sequestered calcium ion into cytosol

Gene Ontology

Source: GO:0051209

Synonyms:

calcium ion (Ca2+) mobilization
calcium mobilization

Branch: biological process

Genes: Plcl1 (Mmu)...plcl1 (Dre)...Plcl1 (Rno)

Genes Annotated with this GO Term (232)

lipid catabolic process

Gene Ontology

Source: GO:0016042

Synonyms:

lipid breakdown
lipid catabolism

Branch: biological process

Genes: Plcl1 (Rno)...PLCL1 (Hsa)...plcl1 (Dre)

Genes Annotated with this GO Term (1443)

phosphoric diester hydrolase activity

Gene Ontology

Source: GO:0008081

Synonyms:

phosphodiesterase

Branch: molecular function

Genes: plcl1 (Dre)

Genes Annotated with this GO Term (456)

lipid metabolic process

Gene Ontology

Source: GO:0006629

Synonyms:

lipid metabolism

Branch: biological process

Genes: Plcl1 (Rno)...PLCL1 (Hsa)...plcl1 (Dre)...Plcl1 (Mmu)

Genes Annotated with this GO Term (5944)

intracellular signal transduction

Gene Ontology

Source: GO:0035556

Synonyms:

intracellular signal transduction pathway
intracellular signaling cascade

Branch: biological process

Genes: Plcl1 (Rno)...PLCL1 (Hsa)...plcl1 (Dre)...Plcl1 (Mmu)

Genes Annotated with this GO Term (7611)

sa41457

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-160601-7453

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: point_mutation

Molecular Consequence: stop_gained

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

sa31726

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-160601-1209

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: point_mutation

Molecular Consequence: stop_gained

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

sa21517

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-161003-11201

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: point_mutation

Molecular Consequence: splice_donor_variant

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

sa34681

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-160601-3315

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: point_mutation

Molecular Consequence: stop_gained

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

sa2490

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-161003-12076

Genes: plcl1 (Dre)

Synonyms: Not Available

Variant Type: point_mutation

Molecular Consequence: splice_donor_variant

Diseases: Not Available

Variant Name: Not Available

Genes: plcl1 (Dre)

(GRCh38)2:197805200T>A

(Homo sapiens)

Allele/Variant

Source: rs1690443549

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:197805200T>A

(GRCh38)2:197987706G>T

(Homo sapiens)

Allele/Variant

Source: rs207462780

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)2:197987706G>T

(GRCh38)2:198084407G>A

(Homo sapiens)

Allele/Variant

Source: rs140990771

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198084407G>A

(GRCh38)2:198085404G>C

(Homo sapiens)

Allele/Variant

Source: rs201079513

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198085404G>C

(GRCh38)2:198085547T>G

(Homo sapiens)

Allele/Variant

Source: rs1419008718

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198085547T>G

(GRCh38)2:198088982T>A

(Homo sapiens)

Allele/Variant

Source: NC_000002.12:g.198088982T>A

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198088982T>A

(GRCh38)2:198088983G>T

(Homo sapiens)

Allele/Variant

Source: rs370504499

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198088983G>T

(GRCh38)2:198248982C>A

(Homo sapiens)

Allele/Variant

Source: rs207462783

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198248982C>A

(GRCh38)2:198084322A>G

(Homo sapiens)

Allele/Variant

Source: NC_000002.12:g.198084322A>G

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198084322A>G

(GRCh38)2:198084653A>G

(Homo sapiens)

Allele/Variant

Source: rs766846507

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198084653A>G

(GRCh38)2:198514921G>T

(Homo sapiens)

Allele/Variant

Source: rs207462784

Genes: PLCL1 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)2:198514921G>T

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