Version: 8.0.0
Date: Tue Jan 28 2025
4,932 results for runx1t1

Runx1t1

(Rattus norvegicus)
Gene
Name: RUNX1 partner transcriptional co-repressor 1
Synonyms: LOC362489, acute myelogenous leukemia 1 translocation 1 protein, runt-related transcription factor 1; translocated to, 1 (cyclin D-related), RUNX1 translocation partner 1, CBFA2T1 identified gene homolog (human), CBFA2T1 identified gene homolog, Cbfa2t1, translocated to, 1, core-binding factor, runt domain, alpha subunit 2, translocated to, 1, core-binding factor, runt domain, alpha subunit 2, runt-related transcription factor 1, cyclin D-related, translocated to, 1 (cyclin D-related)
Source: RGD:1305490
Biotype: protein coding gene
Symbol: Runx1t1 (Rno)
Symbol: Runx1t1
Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1); PARTICIPATES IN acute myeloid
Automated Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Strict Orthology Symbols: runx1t1

runx1t1

(Danio rerio)
Gene
Name: RUNX1 partner transcriptional co-repressor 1
Synonyms: zgc:154044, wu:fi14b07
Source: ZFIN:ZDB-GENE-060929-164
Biotype: protein coding gene
Symbol: runx1t1 (Dre)
Symbol: runx1t1
Automated Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Strict Orthology Symbols: runx1t1

RUNX1T1

(Homo sapiens)
Gene
Name: RUNX1 partner transcriptional co-repressor 1
Synonyms: ETO, acute myelogenous leukemia 1 translocation 1, cyclin-D related, AML1-MTG8, CBFA2T1 isoform r1t1-11a65, CBFA2T1 isoform r1t1-11a64, eight twenty one protein, ZMYND2, MTG8b, CDR, CBFA2T1 isoform r1t1-8a57, CBFA2T1 isoform r1t1-8a58, DKFZp564B213, CBFA2T1 isoform r1t1-8a59, CBFA2T1 isoform r1t1-7a47, translocated to, 1 (cyclin D related), CBFA2T1 isoform r1t1-7a48, translocated to, 1, core-binding factor, runt domain, alpha subunit 2, translocated to, 1, CBFA2T1 isoform r1t1-7a49, FLJ33145, CBFA2T1 isoform r1t1-11a63, CBFA2T1 isoform r1t1-11a62, cyclin-D-related protein, CBFA2T1 isoform r1t1-11a61, core-binding factor, runt domain, alpha subunit 2, runt-related transcription factor 1, MTG8, translocated to, 1 (cyclin D-related), MGC2796, AML1T1, RUNX1 translocation partner 1, CBFA2T1, CBFA2T1 isoform r1t1-7d53, CBFA2T1 isoform r1t1-7d54, runt related transcription factor 1, CBFA2T1 isoform r1t1-7d55, CBFA2T1 isoform r1t1-7d56, CBFA2T1 isoform r1t1-8a60, zinc finger MYND domain-containing protein 2, CBFA2T1 isoform r1t1-7a50, myeloid translocation gene on 8q22, cyclin D-related, CBFA2T1 isoform r1t1-7a51, CBFA2T1 isoform r1t1-7a52
Source: HGNC:1535
Biotype: protein coding gene
Symbol: RUNX1T1 (Hsa)
Symbol: RUNX1T1
Strict Orthology Symbols: runx1t1

Runx1t1

(Mus musculus)
Gene
Name: RUNX1 translocation partner 1
Synonyms: CBFA2T1 identified gene homolog (human), ETO, Cbfa2t1, Cbfa2t1h, MTG8
Source: MGI:104793
Biotype: protein coding gene
Symbol: Runx1t1 (Mmu)
Symbol: Runx1t1
Automated Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Strict Orthology Symbols: runx1t1
Alleles: Runx1t1 (Mmu)...Runx1t1 (Mmu)...Runx1t1 (Mmu)...Runx1t1 (Mmu)...Runx1t1 (Mmu)

runx1t1

(Xenopus tropicalis)
Gene
Name: RUNX1 translocation partner 1
Synonyms: runx1t1, LOC108695382, RUNX1 translocation partner 1
Source: Xenbase:XB-GENE-481238
Biotype: gene
Symbol: runx1t1
Symbol: runx1t1 (Xtr)
Automated Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Synonyms: runx1t1...runx1t1...runx1t1
Strict Orthology Symbols: runx1t1

runx1t1.L

(Xenopus laevis)
Gene
Name: RUNX1 translocation partner 1
Synonyms: runx1t1.L, LOC108695382, RUNX1 translocation partner 1
Source: Xenbase:XB-GENE-865458
Biotype: gene
Symbol: runx1t1.L (Xla)
Automated Gene Synopsis: Orthologous to human RUNX1T1 (RUNX1 partner transcriptional co-repressor 1).
Strict Orthology Symbols: runx1t1
Symbol: runx1t1.L

Runx1t1l

(Rattus norvegicus)
Gene
Name: RUNX1 partner transcriptional co-repressor 1 like
Synonyms: LOC120102834, uncharacterized LOC120102834, uncharacterized protein Runx1t1l, uncharacterized protein LOC120102834
Source: RGD:41195959
Biotype: protein coding gene
Symbol: Runx1t1l (Rno)
Symbol: Runx1t1l

Runx1t1tm1c(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:7703692
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1tm1c(EUCOMM)Hmgu

Runx1t1tm1Fc

(Mus musculus)
Allele/Variant
Source: MGI:2183012
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1tm1Fc

Runx1t1em6Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7305677
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1em6Gpt

Runx1t1tm1Buch

(Mus musculus)
Allele/Variant
Source: MGI:2671472
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1tm1Buch

Runx1t1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7305676
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1em1Gpt

Runx1t1tm1a(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:4881046
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1tm1a(EUCOMM)Hmgu

Runx1t1tm1b(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:6201257
Genes: Runx1t1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Runx1t1 (Mmu)
Genes: Runx1t1 (Mmu)
Symbol: Runx1t1tm1b(EUCOMM)Hmgu

Runx1t1tm1Fc/Runx1t1+ [background:] involves: 129S/SvEv * C57BL/6

(Mus musculus)
Model
Id: MGI:3851363
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1<+> [background:] involves: 129S/SvEv * C57BL/6 (Mmu)
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1<+> [background:] involves: 129S/SvEv * C57BL/6

Runx1t1tm1Buch/Runx1t1+ Runx1tm1Buch/Runx1+ Tg(Nes-cre)1Atp/0 [background:] involves: FVB/N

(Mus musculus)
Model
Id: MGI:2671931
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1<+> Runx1/Runx1<+> Tg(Nes-cre)1Atp/0 [background:] involves: FVB/N
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1<+> Runx1/Runx1<+> Tg(Nes-cre)1Atp/0 [background:] involves: FVB/N

Runx1t1tm1b(EUCOMM)Hmgu/Runx1t1+ [background:] C57BL/6N-Runx1t1tm1b(EUCOMM)Hmgu/H

(Mus musculus)
Model
Id: MGI:6408634
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1<+> [background:] C57BL/6N-Runx1t1/H (Mmu)
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1<+> [background:] C57BL/6N-Runx1t1/H

Runx1t1tm1Fc/Runx1t1tm1Fc [background:] involves: 129S/SvEv * C57BL/6

(Mus musculus)
Model
Id: MGI:2660657
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1 [background:] involves: 129S/SvEv * C57BL/6 (Mmu)
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1 [background:] involves: 129S/SvEv * C57BL/6

Runx1t1tm1Buch/Runx1t1tm1Buch [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:2671479
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1 [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1 [background:] involves: 129P2/OlaHsd

Runx1t1tm1b(EUCOMM)Hmgu/Runx1t1tm1b(EUCOMM)Hmgu [background:] C57BL/6N-Runx1t1tm1b(EUCOMM)Hmgu/H

(Mus musculus)
Model
Id: MGI:6408635
Synonyms: Not Available
Symbol: Runx1t1/Runx1t1 [background:] C57BL/6N-Runx1t1
Genes: Runx1t1 (Mmu)
Alleles: Runx1t1 (Mmu)
Name: Runx1t1/Runx1t1 [background:] C57BL/6N-Runx1t1

nvy

(Drosophila melanogaster)
Gene
Name: nervy
Synonyms: Nvy, nervy, CG3385, Nervy
Source: FB:FBgn0005636
Biotype: protein coding gene
Strict Orthology Symbols: runx1t1

regulation of DNA binding

Gene Ontology
Source: GO:0051101
Synonyms: Not Available
Branch: biological process
Genes: Runx1t1 (Mmu)

f3Tg

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-080506-1
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Constructs: Tg(hsp70:RUNX1T1)...Tg(hsp70l:runx1t1)

Hsap\RUNX1T1UAS.cOa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0239169
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1T1
Construct Expressed Component: RUNX1T1 (Hsa)

negative regulation of fat cell differentiation

Gene Ontology
Source: GO:0045599
Synonyms:
  • down regulation of fat cell differentiation
  • down-regulation of fat cell differentiation
Branch: biological process
Genes: RUNX1T1 (Hsa)...Runx1t1 (Rno)...Runx1t1 (Mmu)

Hsap\RUNX1T1UAS.cIa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0385401
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1T1
Construct Expressed Component: RUNX1T1 (Hsa)

Hsap\RUNX1T1UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276914
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1T1
Construct Expressed Component: RUNX1T1 (Hsa)

fat cell differentiation

Gene Ontology
Source: GO:0045444
Synonyms:
  • adipocyte cell differentiation
  • adipocyte differentiation
Branch: biological process
Genes: Runx1t1 (Rno)...RUNX1T1 (Hsa)...Runx1t1 (Mmu)

acute myeloid leukemia with t(8;21); (q22; q22.1)

Disease
Source: DOID:0081093
Definition: An acute myeloid leukemia associated with t(8;21)(q22;q22) resulting in RUNX1-RUNX1T1 fusion protein expression. The bone marrow and the peripheral blood show large myeloblasts with abundant basophilic cytoplasm, often containing azurophilic granules.

DNA-templated transcription

Gene Ontology
Source: GO:0006351
Synonyms:
  • DNA-dependent transcription
  • bacterial transcription
Branch: biological process
Genes: Runx1t1 (Rno)...Runx1t1 (Mmu)...RUNX1T1 (Hsa)...runx1t1 (Dre)

Hsap\RUNX1::Hsap\RUNX1T1UAS.cMa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0190422
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: acute myeloid leukemia
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Tg(tetO-AML1/RUNX1T1)1Stm

(Mus musculus)
Allele/Variant
Source: MGI:7495817
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Tg(tetO-AML1/RUNX1T1)1Stm

Hsap\RUNX1::Hsap\RUNX1T1YT.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276917
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276915
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: acute myeloid leukemia
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1NHR3X.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276920
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1YTR.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276918
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1ΔZF.UAS

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0189798
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1<ΔZF.UAS>

Hsap\RUNX1::Hsap\RUNX1T1R174Q.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276916
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1NHR2Xm7.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276921
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

Hsap\RUNX1::Hsap\RUNX1T1NHR2X.UAS.cSa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0276919
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\RUNX1::Hsap\RUNX1T1

nuclear matrix

Gene Ontology
Source: GO:0016363
Synonyms:
  • nucleoskeleton
Branch: cellular component
Genes: Runx1t1 (Rno)...Runx1t1 (Mmu)...RUNX1T1 (Hsa)

transcription corepressor activity

Gene Ontology
Source: GO:0003714
Synonyms:
  • RNA polymerase II transcription co-repressor activity
  • RNA polymerase II transcription corepressor activity
Branch: molecular function
Genes: Runx1t1 (Rno)...Runx1t1 (Mmu)...RUNX1T1 (Hsa)...runx1t1 (Dre)

DNA-binding transcription factor binding

Gene Ontology
Source: GO:0140297
Synonyms:
  • activating transcription factor binding
  • repressing transcription factor binding
Branch: molecular function
Genes: Runx1t1 (Rno)...Runx1t1 (Mmu)...RUNX1T1 (Hsa)

transcription repressor complex

Gene Ontology
Source: GO:0017053
Synonyms:
  • cytoplasmic transcriptional repressor complex
  • nuclear transcriptional repressor complex
Branch: cellular component
Genes: Runx1t1 (Mmu)

negative regulation of neuron projection development

Gene Ontology
Source: GO:0010977
Synonyms:
  • growth cone collapse
  • negative regulation of neurite biosynthesis
Branch: biological process
Genes: Runx1t1 (Mmu)

negative regulation of DNA-templated transcription

Gene Ontology
Source: GO:0045892
Synonyms:
  • down regulation of gene-specific transcription
  • down regulation of transcription, DNA-dependent
Branch: biological process
Genes: Runx1t1 (Mmu)...RUNX1T1 (Hsa)...Runx1t1 (Rno)...runx1t1 (Dre)

sa29233

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-13705
Genes: runx1t1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_region_variant, stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: runx1t1 (Dre)

nucleus

Gene Ontology
Source: GO:0005634
Synonyms:
  • cell nucleus
  • horsetail nucleus
Branch: cellular component
Genes: Runx1t1 (Rno)...runx1t1 (Dre)...RUNX1T1 (Hsa)...Runx1t1 (Mmu)

(GRCh38)8:91970796G>A

(Homo sapiens)
Allele/Variant
Source: rs201731257
Genes: RUNX1T1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)8:91970796G>A

(GRCh38)8:91970768C>T

(Homo sapiens)
Allele/Variant
Source: rs569622614
Genes: RUNX1T1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)8:91970768C>T