Version: 8.0.0
Date: Tue Jan 28 2025
631 results for sigmar1

sigmar1

(Danio rerio)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: zgc:56378, oprs1
Source: ZFIN:ZDB-GENE-040426-1006
Biotype: protein coding gene
Symbol: sigmar1 (Dre)
Symbol: sigmar1
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1

Sigmar1

(Mus musculus)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: Sig1R, Oprs1, mSigmaR1, opioid receptor, sigma 1, AL024364, expressed sequence AL024364
Source: MGI:1195268
Biotype: protein coding gene
Symbol: Sigmar1 (Mmu)
Symbol: Sigmar1
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1
Alleles: Sigmar1 (Mmu)...Sigmar1 (Mmu)...Sigmar1 (Mmu)...Sigmar1 (Mmu)...Sigmar1 (Mmu)

SIGMAR1

(Homo sapiens)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: FLJ25585, sigma 1-type opioid receptor, type I sigma receptor, sigma1 receptor, DSMA2, SR-BP, SRBP, SR31747 binding protein 1, aging-associated gene 8 protein, sigma1-receptor, SR-BP1, sigma1R, OPRS1, HMNR2, hSigmaR1, ALS16, SIG-1R, MGC3851, SR31747-binding protein, opioid receptor, sigma 1
Source: HGNC:8157
Biotype: protein coding gene
Symbol: SIGMAR1 (Hsa)
Symbol: SIGMAR1
Strict Orthology Symbols: sigmar1

Sigmar1

(Rattus norvegicus)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: sigma1R, Oprs1, sigma 1-type opioid receptor, opioid receptor, sigma 1, sigma1-receptor
Source: RGD:68364
Biotype: protein coding gene
Symbol: Sigmar1 (Rno)
Symbol: Sigmar1
Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1); INTERACTS WITH 17beta-estradiol
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1

sigmar1

(Xenopus tropicalis)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: sigmar1, sigma non-opioid intracellular receptor 1, oprs1
Source: Xenbase:XB-GENE-5786075
Biotype: gene
Symbol: sigmar1
Symbol: sigmar1 (Xtr)
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Synonyms: sigmar1...sigmar1...sigmar1
Strict Orthology Symbols: sigmar1

sigmar1.L

(Xenopus laevis)
Gene
Name: sigma non-opioid intracellular receptor 1
Synonyms: sigmar1.L, sigma non-opioid intracellular receptor 1, oprs1
Source: Xenbase:XB-GENE-6255099
Biotype: gene
Symbol: sigmar1.L (Xla)
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1
Symbol: sigmar1.L

Sigmar1em28Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7306111
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em28Gpt

Sigmar1tm1(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:4419417
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1tm1(KOMP)Wtsi

Sigmar1Gt(OST422756)Lex

(Mus musculus)
Allele/Variant
Source: MGI:3529055
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1Gt(OST422756)Lex

Sigmar1em2Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7292323
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em2Smoc

Sigmar1tm1.1(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:6120698
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1tm1.1(KOMP)Wtsi

Sigmar1em2Cya

(Mus musculus)
Allele/Variant
Source: MGI:7586510
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em2Cya

Sigmar1tm1Lmon

(Mus musculus)
Allele/Variant
Source: MGI:3044771
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1tm1Lmon

Sigmar1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7306110
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em1Gpt

Sigmar1em1Gan

(Mus musculus)
Allele/Variant
Source: MGI:7525746
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em1Gan

Sigmar1em1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7292322
Genes: Sigmar1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Sigmar1 (Mmu)
Genes: Sigmar1 (Mmu)
Symbol: Sigmar1em1Smoc

Sigmar1tm1Lmon/Sigmar1tm1Lmon [background:] either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)

(Mus musculus)
Model
Id: MGI:3044773
Synonyms: Not Available
Symbol: Sigmar1/Sigmar1 [background:] either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
Genes: Sigmar1 (Mmu)
Alleles: Sigmar1 (Mmu)
Name: Sigmar1/Sigmar1 [background:] either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)

Sigmar1tm1.1(KOMP)Wtsi/Sigmar1tm1.1(KOMP)Wtsi [background:] C57BL/6N-Sigmar1tm1.1(KOMP)Wtsi/BayMmucd

(Mus musculus)
Model
Id: MGI:6772031
Synonyms: Not Available
Symbol: Sigmar1/Sigmar1 [background:] C57BL/6N-Sigmar1/BayMmucd
Genes: Sigmar1 (Mmu)
Alleles: Sigmar1 (Mmu)
Name: Sigmar1/Sigmar1 [background:] C57BL/6N-Sigmar1/BayMmucd

sigmar1f19/f19

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-230711-1
Synonyms: Not Available
Symbol: sigmar1 (Dre)
Genes: sigmar1 (Dre)
Name: sigmar1

sigmar1f20/f20

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160901-21
Synonyms: Not Available
Symbol: sigmar1 (Dre)
Genes: sigmar1 (Dre)
Name: sigmar1

sigmar1f19/f19

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-160901-20
Synonyms: Not Available
Symbol: sigmar1 (Dre)
Genes: sigmar1 (Dre)
Name: sigmar1

Sigmar1Gt(OST422756)Lex/Sigmar1Gt(OST422756)Lex [background:] involves: 129S5/SvEvBrd * C57BL/6J

(Mus musculus)
Model
Id: MGI:3609708
Synonyms: Not Available
Symbol: Sigmar1/Sigmar1 [background:] involves: 129S5/SvEvBrd * C57BL/6J
Genes: Sigmar1 (Mmu)
Alleles: Sigmar1 (Mmu)
Name: Sigmar1/Sigmar1 [background:] involves: 129S5/SvEvBrd * C57BL/6J

ERG2

(Saccharomyces cerevisiae)
Gene
Name: ERGosterol biosynthesis
Synonyms: END11, YMR202W
Source: SGD:S000004815
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1

W08F4.3

(Caenorhabditis elegans)
Gene
Name: Sigma non-opioid intracellular receptor 1
Synonyms: CELE_W08F4.3
Source: WB:WBGene00021093
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Automated Gene Synopsis: Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Strict Orthology Symbols: sigmar1

autosomal recessive distal hereditary motor neuronopathy 2

Disease
Source: DOID:0111065
Definition: A spinal muscular atrophy characterized by autosomal recessive inheritance of distal muscle weakness and muscle wasting primarily affecting the upper and lower limbswith onset typically in the first decade of life that has_material_basis_in homozygous mutation in the SIGMAR1 gene on chromosome 9p13.
Genes: sigmar1 (Xtr)...SIGMAR1 (Hsa)...sigmar1 (Dre)...Sigmar1 (Mmu)...Sigmar1 (Rno)

amyotrophic lateral sclerosis type 16

Disease
Source: DOID:0060207
Definition: An amyotrophic lateral sclerosis that has_material_basis_in mutation in the SIGMAR1 gene (SETX) on chromosome 9.
Genes: sigmar1 (Xtr)...SIGMAR1 (Hsa)...sigmar1 (Dre)...Sigmar1 (Mmu)...Sigmar1 (Rno)

G protein-coupled opioid receptor activity

Gene Ontology
Source: GO:0004985
Synonyms:
  • opioid receptor activity
Branch: molecular function
Genes: SIGMAR1 (Hsa)...Sigmar1 (Mmu)...Sigmar1 (Rno)

protein homotrimerization

Gene Ontology
Source: GO:0070207
Synonyms:
  • protein homotrimer assembly
  • protein homotrimer biosynthesis
Branch: biological process
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)

post-traumatic stress disorder

Disease
Source: DOID:2055
Definition: An anxiety disorder which results from a traumatic experience that results in psychological trauma.
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)...sigmar1 (Dre)...sigmar1 (Xtr)

G protein-coupled opioid receptor signaling pathway

Gene Ontology
Source: GO:0038003
Synonyms:
  • opioid receptor signaling pathway
  • opioid receptor signalling pathway
Branch: biological process
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)

hdb2Tg + MO1-sigmar1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-18643
Synonyms: Not Available
Genes: sigmar1 (Dre)
Name: hdb2Tg + MO1-sigmar1

regulation of neuron apoptotic process

Gene Ontology
Source: GO:0043523
Synonyms:
  • regulation of apoptosis of neuronal cells
  • regulation of apoptosis of neurons
Branch: biological process
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)

regulation of response to endoplasmic reticulum stress

Gene Ontology
Source: GO:1905897
Synonyms:
  • regulation of ER stress response
  • regulation of cellular response to endoplasmic reticulum stress
Branch: biological process
Genes: sigmar1 (Dre)

nuclear outer membrane

Gene Ontology
Source: GO:0005640
Synonyms:
  • nucleus outer envelope
  • perinuclear membrane
Branch: cellular component
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)...sigmar1 (Dre)

nuclear inner membrane

Gene Ontology
Source: GO:0005637
Synonyms:
  • inner envelope
  • inner nuclear membrane
Branch: cellular component
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...sigmar1 (Dre)...Sigmar1 (Mmu)

regulation of cellular respiration

Gene Ontology
Source: GO:0043457
Synonyms: Not Available
Branch: biological process
Genes: sigmar1 (Dre)

Hsap\SIGMAR1UAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0402966
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\SIGMAR1
Construct Expressed Component: SIGMAR1 (Hsa)

Hsap\SIGMAR1UAS.cCa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0359876
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\SIGMAR1
Construct Expressed Component: SIGMAR1 (Hsa)

Hsap\SIGMAR1E102Q.UAS

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0359877
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: amyotrophic lateral sclerosis type 16
Variant Name: Not Available
Symbol: Hsap\SIGMAR1
Construct Expressed Component: SIGMAR1 (Hsa)

regulation of postsynapse assembly

Gene Ontology
Source: GO:0150052
Synonyms: Not Available
Branch: biological process
Genes: SIGMAR1 (Hsa)...Sigmar1 (Rno)...Sigmar1 (Mmu)

retinal rod cell development

Gene Ontology
Source: GO:0046548
Synonyms: Not Available
Branch: biological process
Genes: sigmar1 (Dre)

lipid transport

Gene Ontology
Source: GO:0006869
Synonyms: Not Available
Branch: biological process
Genes: Sigmar1 (Rno)...sigmar1 (Dre)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

swimming behavior

Gene Ontology
Source: GO:0036269
Synonyms:
  • swimming behaviour
Branch: biological process
Genes: sigmar1 (Dre)

lipid droplet

Gene Ontology
Source: GO:0005811
Synonyms:
  • adiposome
  • lipid body
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

growth cone

Gene Ontology
Source: GO:0030426
Synonyms: Not Available
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

postsynaptic density membrane

Gene Ontology
Source: GO:0098839
Synonyms: Not Available
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

anchoring junction

Gene Ontology
Source: GO:0070161
Synonyms:
  • anchoring cell junction
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

nuclear envelope

Gene Ontology
Source: GO:0005635
Synonyms: Not Available
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

postsynaptic density

Gene Ontology
Source: GO:0014069
Synonyms:
  • neuronal postsynaptic density
  • post synaptic density
Branch: cellular component
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)

signaling receptor activity

Gene Ontology
Source: GO:0038023
Synonyms:
  • receptor activity
  • receptor activity involved in signal transduction
Branch: molecular function
Genes: Sigmar1 (Rno)...SIGMAR1 (Hsa)...Sigmar1 (Mmu)