Gene

twist1

Species
Xenopus tropicalis
Symbol
twist1
Name
twist family bHLH transcription factor 1
Synonyms
  • twist
  • twist family bHLH transcription factor 1
Biotype
gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including circulatory system development; pharyngeal system development; and regulation of bone mineralization. Is expressed in ectoderm; mesoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in Sweeney-Cox syndrome; breast cancer (multiple); and synostosis (multiple). Orthologous to human TWIST1 (twist family bHLH transcription factor 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTWIST17 of 9YesYes   
Mus musculusTwist16 of 9YesYes   
Rattus norvegicusTwist16 of 9YesYes   
Xenopus laevistwist1.S1 of 1YesYes           
Xenopus laevistwist1.L1 of 1YesYes           
Danio reriotwist1a7 of 9YesYes   
Danio reriotwist1b4 of 9NoYes   
Drosophila melanogastertwi5 of 9YesYes   
Caenorhabditis eleganshlh-85 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
twist2116777654 of 8  
ptf1a310157442 of 8  
hand243 of 8  
tcf2152 of 8  
figla52 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
43.5510M43.5512M43.5514M43.5516M43.5518M43.5520M43.5522M43.5524M43.5526M43.5528M43.5530M43.5532M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available