Gene

itga6l

Species
Danio rerio
Symbol
itga6l
Name
integrin, alpha 6, like
Synonyms
  • im:6912374
  • si:ch211-221c23.3
Biotype
protein coding gene
Automated Description
Predicted to act upstream of or within cell adhesion and integrin-mediated signaling pathway. Predicted to be located in membrane. Predicted to be part of integrin complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGA6 (integrin subunit alpha 6).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23220
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensITGA63 of 10YesNo  
Mus musculusItga63 of 10YesNo  
Rattus norvegicusItga63 of 9YesNo   
Xenopus tropicalisitga64 of 9YesNo   
Drosophila melanogastermew9 of 10YesYes  
Caenorhabditis elegansina-18 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
itga6a179368496 of 8  
itga6b279165466 of 8  
itga3b380751347 of 8  
itga3a479851317 of 8  
itga8585845282 of 8  
itgav684147282 of 8  
itga9782547272 of 8  
itga5882146282 of 8  
itga11a984142272 of 8  
itga41080445262 of 8  
itga2b1182344252 of 8  
itga2.21280044252 of 8  
itga101381844242 of 8  
itga11b1483142252 of 8  
itga11584240252 of 8  
zmp:00000010821683140232 of 8  
itgam.11784539222 of 8  
itgae.21879837222 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
Homo sapiensITGA6
is implicated injunctional epidermolysis bullosa
  • IAGP
    Homo sapiensITGA6
    is implicated injunctional epidermolysis bullosa with pyloric atresia
    • IAGP
      Mus musculusItga6
      is implicated injunctional epidermolysis bullosa Herlitz type
      • TAS
        Caenorhabditis elegansina-1
        is implicated incancer
        • IMP
        • CEA
          Caenorhabditis elegansina-1
          is implicated inepilepsy
          • IMP
          • CEA
            Showing 1 - 5 of 5 rows
            per page

            Alleles and Variants

            Genome location
            Assembly version
            GRCz11
            Viewer Help
            41.535M41.540M41.545M41.550M41.555M
            Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
            Allele/Variant Symbol
            Allele Synonyms
            Category
            Variant
            Variant type
            Molecular consequence
            Has Disease Annotations
            Has Phenotype Annotations
            sa28357allele with one associated variant
            point mutation
            • splice acceptor variant
            Showing 1 - 1 of 1 rows
            per page

            Transgenic Alleles

            No data available

            Models

            No data available

            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCz11
            Viewer Help
            41.535M41.540M41.545M41.550M41.555M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Must provide at least one subject
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            No data available

            Genetic Interactions

            No data available