Ror^HD_CFD00095

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Species

Drosophila melanogaster

Symbol

Ror^HD_CFD00095

Category

allele

Allele of gene

None

Transgenic Constructs

• P{HD_CFD00095}

Synonyms

• Ror[HD_CFD00095]

Description

UAS regulatory sequences drive expression of two different sgRNAs, both of which target common coding exons within the 5' half of the Ror gene without overlapping the start codon; this is designed to result in an indel (small insertion or deletion mutation) of the target gene in the presence of a source of Cas9. Designed for conditional CRISPR mutagenesis; a GAL4 driver can be used to express the sgRNAs and a UAS-Cas9 transgene in a tissue-specific manner, inducing mutagenesis only in the GAL4-expressing cells.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations