Allele/Variant

Nos2tm1Lau

Species
Mus musculus
Symbol
Nos2tm1Lau
Category
allele
Allele of gene
Nos2
Transgenic Constructs
None
Synonyms
  • iNOS KO
  • iNOS-
Description
A neomycin cassette replaced exons 12 and 13 of the gene, which encode the calmodulin-binding domain. Northern and Western blots of IFNg/LPS-stimulated peritoneal macrophages showed no detectable Nos2 mRNA or protein, respectively.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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