Allele/Variant

Ntf3tm1(Bdnf)Tes

Species
Mus musculus
Symbol
Ntf3tm1(Bdnf)Tes
Category
allele
Allele of gene
Ntf3
Transgenic Constructs
None
Synonyms
  • B/N
Description
Sequences encoding the BDNF protein replaced the entire coding region of the Ntf3 gene. A loxP flanked neomycin cassette was inserted adjacent to the coding region of the gene, but was removed via cre-mediated recombination in the final allele. Northern blot analysis and in situ hybridization analysis confirmed expression of a Bdnf transcript from this allele that mimicked the expression pattern of the endogenous Ntf3.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations