Version: 8.0.0
Date: Tue Jan 28 2025
Actbtm2(Tag)Arge
MGI:3032619
Allele of Actb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Actbtm2(Tag)Arge

Species
Mus musculus
Symbol
Actbtm2(Tag)Arge
Category
allele
Allele of gene
Actb
Transgenic Constructs
None
Synonyms
  • Actbtm1(Tag)Arge
Description
A targeting construct was designed to insert sequence encoding IRES, floxed neo, and the SV40 early region in the 3' untranslated region of beta actin, 55 bp downstream of the stop codon. The sequence encoding the SV40 early region encoded large T, small t, and 17kT. The inserted cassette leaves the endogenous coding region and the 54 bp 'zipcode' that directs cellular localization of beta actin intact. Tag expression is dependent on the removal of the floxed neo cassette (which occurred at low frequency without cre expression).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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