Allele/Variant

Tg(WTbeta2)4Wjk

Species

Mus musculus

Symbol

Tg(WTbeta2)4Wjk

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

Tg(Myh6-ADRB2)4Wjk
TG4

Description

The transgene consists of the human beta-2 adrenergic receptor (ADRB2), an SV40 intron/polyA sequence, and the murine myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6) promoter which directs cardiac-specific overexpression of ADRB2. Transgene expression is detected in cardiac myocytes at levels 200 times greater than in human cardiac tissue.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

ADRB2 (Hsa)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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