Dnmt3b^tm5.2Enl

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Species

Mus musculus

Symbol

Dnmt3b^tm5.2Enl

Category

allele

Allele of gene

Dnmt3b

Transgenic Constructs

None

Synonyms

• Dnmt3b^1lox

Description

This allele was created by crossing Dnmt3b^tm5.1Enl with TNAP-cre mice, thereby excising the floxed segment, which includes exon 19, in the germline. This results in out-of-frame splicing of the mRNAs encoding all three active forms of the protein.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations