Mtor^tm1Yam

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Species

Mus musculus

Symbol

Mtor^tm1Yam

Category

allele

Allele of gene

Mtor

Transgenic Constructs

None

Synonyms

• mTOR^-

Description

Exons 44 to 47, encoding the kinase domain, were replaced by an IRES-Betageo-pA cassette. Northern blot of heterozygous ES cells showed reduced expression and detected a larger transcript, corresponding to the fusion of Frap1 to Betageo. Western blot showed that protein levels were also reduced.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations