Version: 8.0.0
Date: Tue Jan 28 2025
Pfkfb3tm1Jche
MGI:3576782
Allele of Pfkfb3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Pfkfb3tm1Jche

Species
Mus musculus
Symbol
Pfkfb3tm1Jche
Category
allele
Allele of gene
Pfkfb3
Transgenic Constructs
None
Synonyms
  • iPFK2-
Description
A targeting construct was designed to insert a neomycin cassette and a stop codon to replace exons 3-7, the sequence encoding the substrate binding site and magnesium binding site. RT-PCR of heterozygote lung samples showed a 50% decrease in transcript levels.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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