Slc6a6^tm1Jaz

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Species

Mus musculus

Symbol

Slc6a6^tm1Jaz

Category

allele

Allele of gene

Slc6a6

Transgenic Constructs

None

Synonyms

• taut^-

Description

Exons 2 - 4 were replaced with a neo-cassette via homologous recombination. RT-PCR analysis detected only a truncated transcript including exon 5 but missing exons 2 - 4 in homozygous hearts. Taurine uptake activity was severely diminished in cultured cardiomyocytes from homozygous mice.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations