Allele/Variant

Steap3tm1.1Atel

Species
Mus musculus
Symbol
Steap3tm1.1Atel
Category
allele
Allele of gene
Steap3
Transgenic Constructs
None
Synonyms
  • TSAP6 KO
  • TSAP6-
Description
A 46 bp polynucleotide containing a LoxP site was added 404bp upstream exon 2, and a neomycin resistance gene floxed by two LoxP sites was added 533bp downstream exon 3. Cre-mediated excision of exons 2-3 was achieved upon electroporation of a Cre-recombinase expression vector in the correctly targeted ES clones. Protein was undetected in homozygous mutant mice by Western blot analysis and Immnunohistological staining.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations