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Date: Fri Dec 13 2024
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Mtor
tm1.1Clyn
MGI:4820819
Allele of
Mtor
Mus musculus
Summary
Transgenic Constructs
Genomic Variant Information
Variant Molecular Consequences
Phenotypes
Disease Associations
Allele/Variant
Mtor
tm1.1Clyn
Species
Mus musculus
Symbol
Mtor
tm1.1Clyn
Category
allele
Allele of gene
Mtor
Transgenic Constructs
None
Synonyms
None
Description
Cre mediated recombination removed the neo cassette, exon 49, and the modified exon 50. Reduced protein expression was confirmed by western blot analysis on heart and liver extracts from heterozygotes.
Additional Information
Literature
Transgenic Constructs
No data available
Genomic Variant Information
No data available
Variant Molecular Consequences
No data available
Phenotypes
Phenotype
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Annotation details
Source
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References
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abnormal muscle physiology
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
+
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
decreased circulating insulin-like growth factor I level
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
+
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
decreased lean body mass
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
+
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
decreased skeletal muscle weight
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
+
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
embryonic lethality
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
tm1.1Clyn
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
increased total body fat amount
View
Name
Type
Experimental condition
Modifier
References
Mtor
tm1.1Clyn
/Mtor
+
[background:] involves: BALB/c * C57BL/6J
genotype
PMID:20388826
MGI
PMID:20388826
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Disease Associations
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