Allele/Variant

Mtortm1.1Clyn

Species
Mus musculus
Symbol
Mtortm1.1Clyn
Category
allele
Allele of gene
Mtor
Transgenic Constructs
None
Synonyms
None
Description
Cre mediated recombination removed the neo cassette, exon 49, and the modified exon 50. Reduced protein expression was confirmed by western blot analysis on heart and liver extracts from heterozygotes.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal muscle physiology
MGI
decreased circulating insulin-like growth factor I level
MGI
decreased lean body mass
MGI
decreased skeletal muscle weight
MGI
embryonic lethalityMGI
increased total body fat amount
MGI
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Disease Associations

No data available