Allele/Variant

Ntf3tm1.1Eafx

Species
Mus musculus
Symbol
Ntf3tm1.1Eafx
Category
allele
Allele of gene
Ntf3
Transgenic Constructs
None
Synonyms
  • NT-3lox-lacZ
Description
A loxP site was inserted upstream of the coding sequence. A lacZ gene with a 5' loxP site was inserted downstream of the coding sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the second loxP site. Western blot analysis confirmed reduced protein expression in the brain and heart. This allele is hypomorphic. Reporter expression requires cre-mediated removal of the coding sequence.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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