Version: 8.0.0
Date: Tue Jan 28 2025
Tg(LTF-EGFP/cre/PGR)15Klin
MGI:5568730Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(LTF-EGFP/cre/PGR)15Klin

Species
Mus musculus
Symbol
Tg(LTF-EGFP/cre/PGR)15Klin
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Lf-GCrePR1e
  • Tg(LTF-EGFP/Cre/PR1e)15Klin
Description
A construct was generated with a triple-fusion sequence EGFP/cre/PGR (encoding EGFP, cre recombinase, and the human progesterone ligand binding domain - aa F642-L901 of LBD). The fusion gene was cloned downstream of the human lactoferrin promoter (LTF). The LfB-GCrePR1e construct was used for microinjection and 12 founders were obtained. Four founders (#'s 7, 11, 15, and 27) were crossed to R26-lacZ reporter mice. Line 15 was used to generate most of the results in the original study.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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