Version: 8.0.0
Date: Tue Jan 28 2025
Lrit3tm1Lex
MGI:5629558
Allele of Lrit3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Lrit3tm1Lex

Species
Mus musculus
Symbol
Lrit3tm1Lex
Category
allele
Allele of gene
Lrit3
Transgenic Constructs
None
Synonyms
  • Lrt3nob6
Description
Exons 3 and 4 were deleted and replaced by a betageo/puro cassette, with only 21 bp of exon 3 remaining. This was confirmed at the genomic and RNA level. The construct contains a premature stop codon in the first 8 bp of the selection cassette, which is predicted to lead to a truncated 206 amino acid protein lacking presumably the immunoglobulin-like (Ig-like), serine-rich, fibronectin III, transmembrane and PDZ-binding domains.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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