Allele/Variant

Ace2em#Yngh

Species
Mus musculus
Symbol
Ace2em#Yngh
Category
allele
Allele of gene
Ace2
Transgenic Constructs
None
Synonyms
  • ACE2-KO
Description
TALEN technology was used to introduce mutations into exon 2. The population analyzed for phenotype contained individuals with alleles from 3 lines (#17, #20 and #24) containing: (1) a 4 bp deletion; (2) a 10 bp deletion; (3) a 3 bp deletion; (4) a 20 bp deletion with a single bp insertion; and (5) a single bp insertion. Northern blot analysis confirmed reduced expression of a long isoform. The short isoform is not detected in the colon of knock-out or control mice. The pound symbol (#) is used when no line is specified or lines are pooled.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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