Allele/Variant

Relntm1.1Mhat

Species
Mus musculus
Symbol
Relntm1.1Mhat
Category
allele
Allele of gene
Reln
Transgenic Constructs
None
Synonyms
  • deltaC-KI
Description
Exon 65 was replaced with a FLAG epitope, deleting the sequence encoding the C terminal region. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted upstream of the modified exon 65. Western blot analysis confirmed accumulation of the truncated protein within neurons.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal cerebral cortex morphologyMGI
abnormal cortical marginal zone morphologyMGI
abnormal dentate gyrus morphologyMGI
abnormal hippocampus CA1 region morphologyMGI
abnormal hippocampus morphologyMGI
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Disease Associations

No data available