Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Rho-Arl3*Q71L)#Visu
MGI:5806092Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Rho-Arl3*Q71L)#Visu

Species
Mus musculus
Symbol
Tg(Rho-Arl3*Q71L)#Visu
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
The full-length murine Arl3 with the Q71L dominant active mutation is under the control of a 4.4-kb rhodopsin promoter. A tandem C-terminally hemagglutinin (HA) and FLAG fusion tags were added. The rhodopsin promoter drives the expression of the gene as early as postnatal day 4 in rod photoreceptor cells of the retina. Immunoblotting indicates 2.5-fold overexpression of the mutant over endogenous levels. The pound symbol (#) is used when line is not specified and/or lines are pooled.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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