Itm2c^em2(IMPC)Tcp

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Species

Mus musculus

Symbol

Itm2c^em2(IMPC)Tcp

Category

allele

Allele of gene

Itm2c

Transgenic Constructs

None

Synonyms

None

Description

This allele produced from project TCPR0313 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence CCTTTCCGGGAGCGGTGGCG. This resulted in a 15-bp deletion from Chr1:85903021 to 85903035_insT (GRCm38) in ENSMUSE00000330277. This mutation is predicted to cause a frameshift with amino acid changes after residue 48 and early truncation 40 amino acids later (p.R48Efs*42). (GRCm38).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations