Allele/Variant

Il2rbm1Btlr

Species
Mus musculus
Symbol
Il2rbm1Btlr
Category
allele
Allele of gene
Il2rb
Transgenic Constructs
None
Synonyms
  • flybase
Description
ENU-induced T to C transition at base pair 78,491,848 (v38) on chromosome 15, or base pair 19,774 in the GenBank genomic region NC_000081 encoding Il2rb. The mutation corresponds to residue 151 in the mRNA sequence NM_008368 within exon 2 of 10 total exons. The mutation results in a methionine to threonine substitution at position 1 (M1T) in the IL2RB protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Phenotype
Annotation details
Source
References
decreased B cell number
MGI
decreased CD4-positive, alpha-beta T cell number
MGI
decreased CD8-positive, naive alpha-beta T cell number
MGI
increased effector memory CD4-positive, alpha-beta T cell number
MGI
increased effector memory CD8-positive, alpha-beta T cell number
MGI
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Disease Associations