Gene

Fbp2

Species
Drosophila melanogaster
Symbol
Fbp2
Name
Fat body protein 2
Synonyms
  • CG3763
  • Fat Body Protein 2
Biotype
protein coding gene
Automated Description
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be active in cytoplasm. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in colon carcinoma and primary hypertrophic osteoarthropathy. Orthologous to human HPGD (15-hydroxyprostaglandin dehydrogenase).
FB Description
Fat body protein 2 (Fbp2) encodes a 256 amino acid protein that accumulates in the larval fat-body at the third larval and pupal stages. The product of Fbp2 is related to the alcohol dehydrogenase encoded by Adh but has no known enzymatic function. The Fbp2-encoded polypeptide contains 20% methionine, whereas there are no methionines in mature polypeptide encoded by Adh, therefore it is thought to be a sulfur-storage protein at metamorphosis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR44229
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensHPGD6 of 9YesNo   
Mus musculusHpgd4 of 9YesNo   
Rattus norvegicusHpgd4 of 9YesNo   
Danio reriozgc:565856 of 10YesNo  
Danio reriohpgd6 of 10YesNo  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
CG4842125362367 of 8  
CG18814225362347 of 8  
Pdh324659337 of 8  
Adhr425756335 of 8  
Adh525553284 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterFbp2GD1034
  • UASt
Drosophila melanogasterFbp2GLC01665
  • UAS
Drosophila melanogasterFbp2HMS02769
  • UAS
Drosophila melanogasterFbp2KK105614
  • UASt
Drosophila melanogasterFbp2NIG.3763R
  • UASt
Showing 1 - 5 of 5 rows
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
9.4268M9.4270M9.4272M9.4274M9.4276M9.4278M

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

8 interactor genes based on 8 annotations
Fbp2 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
CG8132Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:38944040
protein
CG15754Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG32219Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
E(spl)m8-HLHDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
gsbDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
Rab14Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
RpS15AbDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
βTub85DDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
Showing 1 - 8 of 8 rows
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Genetic Interactions

No data available