Gene

MTA1-like

Species
Drosophila melanogaster
Symbol
MTA1-like
Name
Metastasis associated 1-like
Synonyms
  • CG2244
  • dMTA
Biotype
protein coding gene
Automated Description
Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in chromosome condensation. Located in nucleoplasm. Part of NuRD complex. Is expressed in adult brain cell body rind; organism; primordial germ cell; and spermatozoon. Orthologous to several human genes including MTA1 (metastasis associated 1).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10865
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMTA19 of 9YesYes   
Homo sapiensMTA37 of 9NoYes   
Homo sapiensMTA26 of 9NoYes   
Mus musculusMta19 of 9YesYes   
Mus musculusMta37 of 9NoYes   
Mus musculusMta27 of 9NoYes   
Rattus norvegicusMta38 of 9YesYes   
Rattus norvegicusMta18 of 9YesYes   
Rattus norvegicusMta27 of 9NoYes   
Xenopus tropicalismta18 of 9YesYes   
Xenopus tropicalismta27 of 9NoYes   
Danio reriomta18 of 10YesYes  
Danio reriomta28 of 10YesYes  
Danio reriomta37 of 10NoYes  
Caenorhabditis eleganslin-407 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
CG1620153140243 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
fertile
viable
Showing 1 - 2 of 2 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
5.639M5.640M5.641M5.642M5.643M5.644M5.645M5.646M5.647M5.648M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
MTA1-likeMI01790
  • MTA1-like[MI01790]
allele with one associated variant
insertion
  • intron variant
Yes
MTA1-likeMI01790-TG4.1
  • MTA1-like[MI01790-TG4.1]
allele with one associated variant
insertion
  • intron variant
MTA1-likeMI01790-GFSTF.1
  • MTA1-like[MI01790-GFSTF.1]
allele with one associated variant
insertion
  • intron variant
Yes
MTA1-likeEY10750
  • MTA1-like[EY10750]
allele with one associated variant
insertion
  • intron variant
Yes
MTA1-liked00901
  • MTA1-like[d00901]
allele with one associated variant
insertion
  • intron variant
MTA1-like06-040
  • MTA1-like[06-040]
allele with one associated variant
point mutation
  • synonymous variant
MTA1-likeDP00445
  • MTA1-like[DP00445]
allele with one associated variant
insertion
  • intron variant
MTA1-liked09140
  • MTA1-like[d09140]
allele with one associated variant
insertion
  • intron variant
MTA1-likeCPTI000256
  • MTA1-like[CPTI000256]
  • MTA1-like[CPTI256]
allele with one associated variant
insertion
  • 5 prime UTR variant
MTA1-likeCPTI001990
  • MTA1-like[CPTI001990]
allele with one associated variant
insertion
  • intron variant
Showing 1 - 10 of 131 rows
per page

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterMTA1-like+tCH322-20A12
Drosophila melanogasterMTA1-likeGD3908
  • UASt
Drosophila melanogasterMTA1-likeGD9759
  • UASt
Drosophila melanogasterMTA1-likeGFP.FPTB
Drosophila melanogasterMTA1-likeHD_CFD00429
  • UAS
Drosophila melanogasterMTA1-likeHMS01084
  • UAS
Drosophila melanogasterMTA1-likeHMS01251
  • UAS
Drosophila melanogasterMTA1-likeHMS01299
  • UAS
Drosophila melanogasterMTA1-likeKK108061
  • UASt
Drosophila melanogasterMTA1-likeTOE.GS02245
Showing 1 - 10 of 11 rows
per page

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.639M5.640M5.641M5.642M5.643M5.644M5.645M5.646M5.647M5.648MMTA1-like-RA (MTA1-like)MTA1-like-RB (MTA1-like)MTA1-like-RC (MTA1-like)MTA1-like-RD (MTA1-like)CG12170-RA (CG12170)

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

13 interactor genes based on 35 annotations
MTA1-like molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Caf1-55Drosophila melanogaster
protein
  • molecular sieving
PMID:27117189
protein
Caf1-55Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:27117189
protein
Caf1-55Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:27117189
protein
Caf1-55Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:31713634
protein
Caf1-55Drosophila melanogaster
protein
  • molecular sieving
PMID:32499524
protein
Caf1-55Drosophila melanogaster
protein
  • two hybrid
PMID:15516265
protein
Caf1-55Drosophila melanogaster
protein
  • affinity chromatography technology
PMID:24920672
protein
Caf1-55Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:38944040
protein
CDK2AP1Drosophila melanogaster
protein
  • anti bait coimmunoprecipitation
PMID:20733004
protein
CG10431Drosophila melanogaster
protein
  • two hybrid array
PMID:30995488
Showing 1 - 10 of 35 rows
per page

Genetic Interactions

No data available