Gene

Abcd3

Species
Drosophila melanogaster
Symbol
Abcd3
Name
ATP binding cassette subfamily D member 3
Synonyms
  • ABCD
  • ABCD3
Biotype
protein coding gene
Automated Description
Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transmembrane transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in membrane. Predicted to be active in peroxisomal membrane. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in Zellweger syndrome and congenital bile acid synthesis defect 5. Orthologous to human ABCD3 (ATP binding cassette subfamily D member 3).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11384
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensABCD39 of 9YesYes   
Mus musculusAbcd39 of 9YesYes   
Rattus norvegicusAbcd39 of 9YesYes   
Xenopus tropicalisabcd35 of 9YesYes   
Danio rerioabcd3a9 of 10YesYes  
Danio rerioabcd3b9 of 10YesYes  
Caenorhabditis eleganspmp-19 of 9YesYes   
Caenorhabditis eleganspmp-29 of 9YesYes   
Saccharomyces cerevisiaePXA15 of 9YesNo   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Abcd1169855357 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
19.751M19.752M19.753M19.754M19.755M19.756M19.757M19.758M19.759M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
Abcd3EY09231
  • Abcd3[EY09231]
  • Pmp70[EY09231]
allele
Abcd3KG08105
  • Abcd3[KG08105]
  • CG12703[KG08105]
allele with one associated variant
insertion
  • 5 prime UTR variant
NC_004354.4:g.19756386A>Tvariant
SNP
  • intron variant
NC_004354.4:g.19755586T>Cvariant
SNP
  • intron variant
NC_004354.4:g.19755768G>Avariant
SNP
  • intron variant
NC_004354.4:g.19754032A>Gvariant
SNP
  • intron variant
NC_004354.4:g.19754090A>Gvariant
SNP
  • intron variant
NC_004354.4:g.19755165T>Cvariant
SNP
  • intron variant
NC_004354.4:g.19753365G>Tvariant
SNP
  • intron variant
NC_004354.4:g.19755770G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 214 rows
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Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterAbcd3GD3688
  • UASt
Drosophila melanogasterAbcd3HMS01338
  • UAS
Drosophila melanogasterAbcd3KK101428
  • UASt
Drosophila melanogasterAbcd3TKO.GS02476
Drosophila melanogasterAbcd3TOE.GS03151
Drosophila melanogasterAbcd3UAS.ECFP
  • UAS
Showing 1 - 6 of 6 rows
per page

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
19.751M19.752M19.753M19.754M19.755M19.756M19.757M19.758M19.759MAbcd3-RA (Abcd3)Abcd3-RB (Abcd3)Abcd3-RC (Abcd3)Abcd3-RD (Abcd3)CG12702-RA (CG12702)CG12702-RB (CG12702)CG12702-RC (CG12702)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

15 interactor genes based on 16 annotations
Abcd3 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
C1GalTADrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG1105Drosophila melanogaster
protein
  • affinity chromatography technology
PMID:38270169
protein
CG5225Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG9547Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
CG15141Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
eygDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
gcm2Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Gtpbp2Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
kermitDrosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
me31BDrosophila melanogaster
protein
  • proximity labelling technology
PMID:35020877
Showing 1 - 10 of 16 rows
per page

Genetic Interactions

No data available