Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | NUP50 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Mus musculus | Nup50 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Mus musculus | Nup50l | 7 of 9 | No | Yes | ☑ ☑☑☐☑☑☑☐☑ |
Rattus norvegicus | Nup50 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Rattus norvegicus | Nup50-ps1 | 8 of 9 | No | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Xenopus tropicalis | nup50 | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
Danio rerio | nup50 | 9 of 10 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ ☐ |
Caenorhabditis elegans | npp-16 | 7 of 9 | Yes | Yes | ☑ ☐☑☑☑☑☑☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
long lived |
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
---|---|---|---|---|---|---|---|---|
Drosophila melanogaster | Nup50 | is implicated in | neurodegenerative disease |
|
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Nup50KG09557 |
| allele with one associated variant | insertion
| Yes | |||
Nup50e02135 |
| allele with one associated variant | insertion
| ||||
NT_033778.4:g.8123152A>T | variant | SNP
| |||||
NT_033778.4:g.8123399G>T | variant | SNP
| |||||
NT_033778.4:g.8123556T>C | variant | SNP
| |||||
NT_033778.4:g.8124057C>T | variant | SNP
| |||||
NT_033778.4:g.8124207A>C | variant | SNP
| |||||
NT_033778.4:g.8124405A>T | variant | SNP
| |||||
NT_033778.4:g.8124498T>A | variant | SNP
| |||||
NT_033778.4:g.8123398T>C | variant | SNP
|
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Drosophila melanogaster | Nup50GD9739 |
| |||||
Drosophila melanogaster | Nup50HMS01054 |
| |||||
Drosophila melanogaster | Nup50KK108150 |
| Yes | ||||
Drosophila melanogaster | Nup50TKO.GS04125 | ||||||
Drosophila melanogaster | Nup50U6.NIG.sgRNA |
all annotations | all anatomical structures | alimentary part of gastrointestinal system | chemosensory system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | mechanosensory system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | sensory system | vestibulo-auditory system | visual system | endoderm | ectoderm | mesoderm | mesenchyme | adipose tissue | appendage | entire extraembryonic component | imaginal precursor | pharyngeal arch | other | all stages | embryo stage | post embryonic, pre-adult | post-juvenile adult stage | all cellular components | extracellular region | plasma membrane | synapse | cell junction | cell projection | cytoplasmic vesicle | endosome | vacuole | golgi apparatus | endoplasmic reticulum | cytosol | mitochondrion | nucleus | chromosome | cytoskeleton | protein-containing complex | other locations | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nup50 (Dme) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nup50 (Mmu) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Nup50 (Rno) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
nup50 (Dre) |
Nup50 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | Brca2 | Drosophila melanogaster | protein |
| PMID:25588834 | |
protein | Ccn | Drosophila melanogaster | protein |
| PMID:14605208 | |
protein | CG13407 | Drosophila melanogaster | protein |
| PMID:14605208 | |
protein | CG15167 | Drosophila melanogaster | protein |
| PMID:14605208 | |
protein | CG30447 | Drosophila melanogaster | protein |
| PMID:22036573 | |
protein | CG30447 | Drosophila melanogaster | protein |
| FB:FBrf0235788 | |
protein | CG30447 | Drosophila melanogaster | protein |
| FB:FBrf0235788 | |
protein | CG32354 | Drosophila melanogaster | protein |
| PMID:14605208 | |
protein | csw | Drosophila melanogaster | protein |
| PMID:22028469 | |
protein | dos | Drosophila melanogaster | protein |
| PMID:22028469 |
Nup50 role | Nup50 genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
suppressor gene | dom | Drosophila melanogaster | suppressed gene | genetic suppression | PMID:26555684 |