Gene

DMAP1

Species
Drosophila melanogaster
Symbol
DMAP1
Name
DNA methyltransferase 1 associated protein 1
Synonyms
  • CG11132
  • dDMAP1
Biotype
protein coding gene
Automated Description
Predicted to enable transcription corepressor activity. Involved in DNA repair-dependent chromatin remodeling; positive regulation of antimicrobial peptide production; and positive regulation of innate immune response. Located in nucleus. Part of NuA4 histone acetyltransferase complex. Is expressed in organism. Orthologous to human DMAP1 (DNA methyltransferase 1 associated protein 1).
FB Description
DNA methyltransferase 1 associated protein 1 (DMAP1) encodes an evolutionarily conserved nuclear innate immune factor. It interacts with the NF-kappaB transcription factor encoded by Rel and modulates the activation of the immune deficiency pathway in complex with chromatin remodeling factors. Its roles also include larval-pupal development and cell survival.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12855
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensDMAP19 of 9YesYes   
Mus musculusDmap19 of 9YesYes   
Rattus norvegicusDmap19 of 9YesYes   
Xenopus tropicalisdmap18 of 9YesYes   
Danio reriodmap19 of 10YesYes  
Caenorhabditis elegansekl-49 of 9YesYes   
Saccharomyces cerevisiaeSWC47 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
20.6442M20.6444M20.6446M20.6448M20.6450M20.6452M20.6454M20.6456M20.6458M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NT_033778.4:g.20644054T>Avariant
SNP
  • 5 prime UTR variant
NT_033778.4:g.20644812T>Cvariant
SNP
  • synonymous variant
NT_033778.4:g.20645196C>Gvariant
SNP
  • synonymous variant
NT_033778.4:g.20645492A>Tvariant
SNP
  • synonymous variant
NT_033778.4:g.20644410G>Avariant
SNP
  • synonymous variant
NT_033778.4:g.20644473C>Tvariant
SNP
  • synonymous variant
NT_033778.4:g.20644727T>Cvariant
SNP
  • intron variant
NT_033778.4:g.20645214G>Cvariant
SNP
  • synonymous variant
NT_033778.4:g.20645226A>Cvariant
SNP
  • synonymous variant
NT_033778.4:g.20645411A>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 91 rows
per page

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterDMAP1GD7209
  • UASt
Drosophila melanogasterDMAP1HMJ30233
  • UAS
Drosophila melanogasterDMAP1KK102260
  • UASt
Drosophila melanogasterDMAP1NIG.11132R
  • UASt
Drosophila melanogasterDMAP1U6.NIG.sgRNA
Drosophila melanogasterDMAP1UAS.ORF.Tag:HA
  • UASt
Drosophila melanogasterDMAP1UAS.ORF
  • UASt
Drosophila melanogasterDMAP1VSH330405
  • UAS
Showing 1 - 8 of 8 rows
per page

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
20.6442M20.6444M20.6446M20.6448M20.6450M20.6452M20.6454M20.6456M20.6458MDMAP1-RA (DMAP1)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

13 interactor genes based on 15 annotations
DMAP1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
akirinDrosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:24947515
protein
Bap55Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
Bap55Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:24947515
protein
CG1620Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG5973Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG8745Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG8745Drosophila melanogaster
protein
  • anti tag coimmunoprecipitation
PMID:38944040
protein
CG13605Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
Cog6Drosophila melanogaster
protein
  • two hybrid
PMID:14605208
protein
domDrosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
Showing 1 - 10 of 15 rows
per page

Genetic Interactions

No data available