Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | PLEKHM1 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Homo sapiens | PLEKHM3 | 4 of 9 | No | Yes | ☑ ☐☐☐☑☑☑☐☐ |
Mus musculus | Plekhm1 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Mus musculus | Plekhm3 | 4 of 9 | No | Yes | ☑ ☐☐☐☑☑☑☐☐ |
Rattus norvegicus | Plekhm1 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Rattus norvegicus | Plekhm3 | 4 of 9 | No | Yes | ☑ ☐☐☐☑☑☑☐☐ |
Xenopus tropicalis | plekhm3 | 4 of 9 | Yes | Yes | ☑ ☐☐☐☑☑☑☐☐ |
Danio rerio | plekhm1 | 8 of 10 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ ☐ |
Danio rerio | plekhm3 | 4 of 10 | No | Yes | ☑ ☐☐☐☑☑☑☐☐ ☐ |
Caenorhabditis elegans | cup-14 | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
---|---|---|---|---|---|---|---|---|
Homo sapiens | PLEKHM1 | is implicated in | autosomal recessive osteopetrosis 6 |
| ||||
Homo sapiens | PLEKHM1 | is implicated in | osteopetrosis |
| ||||
Mus musculus | Plekhm1 | is implicated in | autosomal recessive osteopetrosis 6 |
|
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Plekhm1d18 |
| allele | |||||
Plekhm1d14 |
| allele | |||||
NT_033778.4:g.22104451T>C | variant | SNP
| |||||
NT_033778.4:g.22104728G>A | variant | SNP
| |||||
NT_033778.4:g.22105803T>C | variant | SNP
| |||||
NT_033778.4:g.22104001C>T | variant | SNP
| |||||
NT_033778.4:g.22104169G>A | variant | SNP
| |||||
NT_033778.4:g.22103494C>T | variant | SNP
| |||||
NT_033778.4:g.22103656A>G | variant | SNP
| |||||
NT_033778.4:g.22103794G>T | variant | SNP
|
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Drosophila melanogaster | Plekhm1GD11978 |
| |||||
Drosophila melanogaster | Plekhm1HMJ23550 |
| |||||
Drosophila melanogaster | Plekhm1HMS23559 |
| |||||
Drosophila melanogaster | Plekhm1KK100096 |
| |||||
Drosophila melanogaster | Plekhm1U6.NIG.sgRNA | ||||||
Drosophila melanogaster | Plekhm1UAS.ORF.Tag:HA |
|
| ||||
Drosophila melanogaster | Plekhm1UAS.ORF |
|
all annotations | all anatomical structures | alimentary part of gastrointestinal system | chemosensory system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | mechanosensory system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | sensory system | vestibulo-auditory system | visual system | endoderm | ectoderm | mesoderm | mesenchyme | adipose tissue | appendage | entire extraembryonic component | imaginal precursor | pharyngeal arch | other | all stages | embryo stage | post embryonic, pre-adult | post-juvenile adult stage | all cellular components | extracellular region | plasma membrane | synapse | cell junction | cell projection | cytoplasmic vesicle | endosome | vacuole | golgi apparatus | endoplasmic reticulum | cytosol | mitochondrion | nucleus | chromosome | cytoskeleton | protein-containing complex | other locations | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plekhm1 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | DEF8 | Drosophila melanogaster | protein |
| PMID:22036573 | |
protein | Rab7 | Drosophila melanogaster | protein |
| PMID:25453831 | |
protein | Rab7 | Drosophila melanogaster | protein |
| PMID:25453831 | |
protein | Rab7 | Drosophila melanogaster | protein |
| PMID:25453831 | |
protein | Rab7 | Drosophila melanogaster | protein |
| PMID:28483915 |