Gene

TAS1R3

Species
Homo sapiens
Symbol
TAS1R3
Name
taste 1 receptor member 3
Synonyms
  • sweet taste receptor T1R3
  • T1R3
Biotype
protein coding gene
Automated Description
Contributes to sweet taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of sweet taste and sensory perception of umami taste. Located in Golgi apparatus and plasma membrane. Part of sweet taste receptor complex.
RGD Description
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24061
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Mus musculusTas1r310 of 10YesYes  
Rattus norvegicusTas1r310 of 10YesYes  
Danio reriotas1r310 of 10YesYes  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
TAS1R1189548313 of 8  
CASR294546283 of 8  
GPRC6A389948283 of 8  
TAS1R2490547283 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    GRCh38
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_000001.11:g.1332283C>Tvariant
    SNP
    • missense variant
    NC_000001.11:g.1332630G>Tvariant
    SNP
    • missense variant
    NC_000001.11:g.1332714G>Avariant
    SNP
    • missense variant
    NC_000001.11:g.1332775G>Avariant
    SNP
    • missense variant
    NC_000001.11:g.1333083A>Tvariant
    SNP
    • missense variant
    NC_000001.11:g.1333696A>Cvariant
    SNP
    • synonymous variant
    NC_000001.11:g.1333869C>Tvariant
    SNP
    • missense variant
    NC_000001.11:g.1333940C>Tvariant
    SNP
    • missense variant
    NC_000001.11:g.1332620G>Cvariant
    SNP
    • missense variant
    NC_000001.11:g.1333046G>Cvariant
    SNP
    • missense variant
    Showing 1 - 10 of 126 rows
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCh38
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    13 interactor genes based on 13 annotations
    TAS1R3 molecule type
    Interactor gene
    Interactor species
    Interactor molecule type
    Detection methods
    Source
    Reference
    protein
    ACP2Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    GJA1Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    HOXD13Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    HYAL2Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    RNA
    LINC00839Homo sapiens
    protein
    • unspecified method
    PMID:30631154
    protein
    LRRC3Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    RNF123Homo sapiens
    protein
    • affinity chromatography technology
    PMID:29676528
    protein
    STIM1Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    SUN1Homo sapiens
    protein
    • affinity chromatography technology
    PMID:33961781
    protein
    TAS1R1Homo sapiens
    protein
    • affinity chromatography technology
    PMID:11894099
    Showing 1 - 10 of 13 rows
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    Genetic Interactions

    No data available