Gene

C2cd2l

Species
Mus musculus
Symbol
C2cd2l
Name
C2 calcium-dependent domain containing 2-like
Synonyms
  • 1300006O23Rik
  • RIKEN cDNA 1300006O23 gene
Biotype
protein coding gene
Automated Description
Enables insulin binding activity. Acts upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in membrane. Is expressed in jaw bone; nervous system; neural retina; and thoracic segment skeleton. Orthologous to human C2CD2L (C2CD2 like).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21119
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensC2CD2L10 of 10YesYes  
Rattus norvegicusC2cd2l9 of 9YesYes   
Xenopus tropicalisc2cd2l9 of 9YesYes   
Danio rerioc2cd2l10 of 10YesYes  
Drosophila melanogasterCG107373 of 9YesYes   
Caenorhabditis eleganstmem-243 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
C2cd2176348323 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal auditory brainstem response
decreased exploration in new environment
decreased startle reflex
Showing 1 - 3 of 3 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
GRCm39
Viewer Help
44.221M44.222M44.223M44.224M44.225M44.226M44.227M44.228M44.229M44.230M44.231M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
C2cd2lem1Gpt
  • C2cd2lem1Cflox
allele
C2cd2lem3Gpt
  • C2cd2lem3Cd6604
allele
C2cd2lem1(IMPC)Jallele
Yes
NC_000075.7:g.44221327T>Gvariant
SNP
  • 3 prime UTR variant
NC_000075.7:g.44225127T>Cvariant
SNP
  • intron variant
NC_000075.7:g.44225606G>Cvariant
SNP
  • intron variant
NC_000075.7:g.44227118C>Tvariant
SNP
  • intron variant
NC_000075.7:g.44227391A>Gvariant
SNP
  • intron variant
NC_000075.7:g.44227779G>Avariant
SNP
  • intron variant
NC_000075.7:g.44229550A>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 249 rows
per page

Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
C2cd2lem1(IMPC)J/C2cd2lem1(IMPC)J [background:] C57BL/6NJ-C2cd2lem1(IMPC)J/Mmjax
  • abnormal auditory brainstem response
  • decreased exploration in new environment
MGI
Showing 1 - 1 of 1 rows
per page

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
44.221M44.222M44.223M44.224M44.225M44.226M44.227M44.228M44.229M44.230M44.231MENSMUST00000065080 (C2cd2l)ENSMUST00000213160 (C2cd2l)ENSMUST00000214602 (C2cd2l)ENSMUST00000216222 (C2cd2l)NM_001359259.1 (C2cd2l)NM_027909.2 (C2cd2l)

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
C2cd2l (Mmu)
CG10737 (Dme)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

8 interactor genes based on 8 annotations
C2cd2l molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Brsk2Mus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
Cyfip2Mus musculus
protein
  • affinity chromatography technology
PMID:32560809
protein
Epb41Mus musculus
protein
  • biochemical
PMID:32325033
protein
Gria2Mus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
LnpkMus musculus
protein
  • proximity labelling technology
PMID:36417873
protein
Lnx2Mus musculus
protein
  • affinity chromatography technology
PMID:27889896
protein
Sting1Mus musculus
protein
  • proximity labelling technology
PMID:32554809
protein
Usp48Mus musculus
protein
  • affinity chromatography technology
PMID:36293380
Showing 1 - 8 of 8 rows
per page

Genetic Interactions

No data available