Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | CERS5 | 9 of 10 | Yes | Yes | ☐☑☑☑☑☑☑☑☑☑ |
Rattus norvegicus | Cers5 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | cers5 | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
Danio rerio | cers5 | 8 of 10 | Yes | Yes | ☑ ☑☐☑☑☑☑☑☐ ☑ |
Drosophila melanogaster | schlank | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Caenorhabditis elegans | hyl-1 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Caenorhabditis elegans | hyl-2 | 8 of 9 | No | Yes | ☑ ☐☑☑☑☑☑☑☑ |
Saccharomyces cerevisiae | LAG1 | 6 of 9 | Yes | No | ☑ ☑☑☐☑☐☑☐☑ |
Saccharomyces cerevisiae | LAC1 | 6 of 9 | Yes | No | ☑ ☑☑☐☑☐☑☐☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
Cers6 | 1 | 383 | 77 | 61 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
Cers4 | 2 | 399 | 59 | 40 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
Cers2 | 3 | 376 | 59 | 41 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
Cers3 | 4 | 378 | 56 | 41 | 7 of 9 | ☑☐☑☐☑☑☑☑☑ |
Cers1 | 5 | 347 | 39 | 26 | 3 of 9 | ☐☐☐☐☐☑☑☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
abnormal bone structure | ||
abnormal motor coordination/balance | ||
decreased bone mineral content | ||
decreased bone mineral density | ||
decreased exploration in new environment | ||
decreased thigmotaxis | ||
increased circulating sodium level |
Species | Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
---|---|---|---|---|---|---|---|---|
Saccharomyces cerevisiae | LAG1 | is implicated in | hepatocellular carcinoma |
| ||||
Saccharomyces cerevisiae | LAG1 | is implicated in | steatotic liver disease |
| ||||
Saccharomyces cerevisiae | LAG1 | is implicated in | type 2 diabetes mellitus |
|
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Cers5tm2b(KOMP)Mbp | allele | Yes | |||||
Cers5tm2a(KOMP)Mbp | allele | ||||||
Cers5em1Gpt |
| allele | |||||
Cers5tm1.1Mhoc |
| allele | |||||
Cers5tm1a(KOMP)Mbp | allele | ||||||
Cers5em2Btlr | allele with one associated variant | deletion
| |||||
Cers5em1Btlr | allele with one associated variant | deletion
| |||||
NC_000081.7:g.99636769C>T | variant | SNP
| |||||
NC_000081.7:g.99634873G>T | variant | SNP
| |||||
NC_000081.7:g.99637827A>G | variant | SNP
|
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
---|---|---|---|---|---|
Cers5tm2b(KOMP)Mbp/Cers5tm2b(KOMP)Mbp [background:] B6N(Cg)-Cers5tm2b(KOMP)Mbp/J |
| MGI |
all annotations | all anatomical structures | alimentary part of gastrointestinal system | chemosensory system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | mechanosensory system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | sensory system | vestibulo-auditory system | visual system | endoderm | ectoderm | mesoderm | mesenchyme | adipose tissue | appendage | entire extraembryonic component | imaginal precursor | pharyngeal arch | other | all stages | embryo stage | post embryonic, pre-adult | post-juvenile adult stage | all cellular components | extracellular region | plasma membrane | synapse | cell junction | cell projection | cytoplasmic vesicle | endosome | vacuole | golgi apparatus | endoplasmic reticulum | cytosol | mitochondrion | nucleus | chromosome | cytoskeleton | protein-containing complex | other locations | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cers5 (Mmu) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
cers5 (Dre) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
schlank (Dme) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
hyl-1 (Cel) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cers5 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | Cfd | Mus musculus | protein |
| PMID:30550785 | |
protein | Ewsr1 | Mus musculus | protein |
| PMID:20211142 | |
protein | Fndc5 | Mus musculus | protein |
| PMID:30550785 | |
protein | Kctd13 | Mus musculus | protein |
| PMID:37142655 | |
protein | Sertad1 | Mus musculus | protein |
| PMID:20211142 | |
protein | Sting1 | Mus musculus | protein |
| PMID:32554809 | |
protein | Wwtr1 | Mus musculus | protein |
| PMID:20211142 |