Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | IRGM | 6 of 10 | Yes | Yes | ☐☑☐☐☐☑☑☑☑☑ |
Gene symbol | Rank | Alignment Length (aa) | Similarity % | Identity % | Method Count | Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD |
---|---|---|---|---|---|---|
Igtp | 1 | 411 | 64 | 51 | 6 of 9 | ☑☐☐☐☑☑☑☑☑ |
Irgm1 | 2 | 407 | 61 | 46 | 6 of 9 | ☑☐☐☐☑☑☑☑☑ |
9930111J21Rik1 | 3 | 417 | 48 | 31 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Gm12185 | 4 | 412 | 49 | 31 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Gm5431 | 5 | 395 | 49 | 31 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Gm4841 | 6 | 409 | 47 | 28 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Irgc | 7 | 401 | 48 | 30 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
F830016B08Rik | 8 | 410 | 46 | 28 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Tgtp2 | 9 | 352 | 53 | 33 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Tgtp1 | 9 | 352 | 53 | 33 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Iigp1 | 10 | 372 | 50 | 28 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Ifi47 | 11 | 318 | 50 | 34 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Iigp1c | 12 | 307 | 54 | 33 | 3 of 9 | ☑☐☐☐☐☐☑☑☐ |
Phenotype Term | Annotation details | References |
---|---|---|
abnormal coat appearance | ||
abnormal lens morphology | ||
abnormal skin morphology | ||
abnormal startle reflex | ||
absent vibrissae | ||
decreased circulating serum albumin level | ||
decreased thigmotaxis | ||
increased susceptibility to parasitic infection | ||
increased susceptibility to parasitic infection induced morbidity/mortality |
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Irgm2tm1.1Jcrs |
| allele | |||||
Irgm2tm1.2Jcrs | allele | ||||||
Irgm2em2Myam | allele | ||||||
Irgm2em1Myam |
| allele | Yes | ||||
Irgm2em1Gpt |
| allele | |||||
Irgm2em3Gpt |
| allele | |||||
Irgm2em1(IMPC)J |
| allele | Yes | ||||
NC_000077.7:g.58101462C>T | variant | SNP
| |||||
NC_000077.7:g.58102482T>C | variant | SNP
| |||||
NC_000077.7:g.58099289A>T | variant | SNP
|
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
---|---|---|---|---|---|
Igtpem1Myam/Igtpem1Myam Irgm1em1Myam/Irgm1em1Myam Irgm2em2Myam/Irgm2em2Myam [background:] C57BL/6-Irgm1em1Myam Igtpem1Myam Irgm2em2Myam |
| MGI | |||
Irgm2em1(IMPC)J/Irgm2em1(IMPC)J [background:] C57BL/6NJ-Irgm2em1(IMPC)J/J |
| MGI | |||
Irgm2em1Myam/Irgm2em1Myam [background:] C57BL/6-Irgm2em1Myam |
| MGI |
Irgm2 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | Cfd | Mus musculus | protein |
| PMID:30550785 | |
protein | Fndc5 | Mus musculus | protein |
| PMID:30550785 |
Irgm2 role | Irgm2 genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
unspecified role | Fitm2 | Mus musculus | unspecified role | positive genetic interaction (sensu BioGRID) |
| PMID:32968282 |