Gene

Uck2

Species
Mus musculus
Symbol
Uck2
Name
uridine-cytidine kinase 2
Synonyms
  • AA407809
  • AI481316
Biotype
protein coding gene
Automated Description
Predicted to enable cytidine kinase activity; identical protein binding activity; and uridine kinase activity. Predicted to be involved in CTP salvage and UMP salvage. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; cranium; integumental system; nervous system; and sensory organ. Orthologous to human UCK2 (uridine-cytidine kinase 2).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10285
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensUCK29 of 10YesYes  
Rattus norvegicusUck29 of 9YesYes   
Xenopus tropicalisuck29 of 9YesYes   
Danio reriouck2a10 of 10YesYes  
Danio reriouck2b5 of 10NoYes  
Drosophila melanogasterUck9 of 9YesYes   
Caenorhabditis elegansB0001.47 of 9YesYes   
Saccharomyces cerevisiaeDAS23 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Uck1130169597 of 9 
Uckl1226763444 of 9 
Uprt322935213 of 9 
Nmrk1415533162 of 9 
Nmrk2511840202 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
abnormal skin morphology
decreased mean corpuscular hemoglobin concentration
increased mean corpuscular volume
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

No mapped variant information available
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
Uck2em1(IMPC)Jallele
Yes
Uck2em8Gpt
  • Uck2em8Cd5915
allele
NC_000067.7:g.167056404A>Gvariant
SNP
  • intron variant
NC_000067.7:g.167056776C>Tvariant
SNP
  • intron variant
NC_000067.7:g.167073945G>Avariant
SNP
  • intron variant
NC_000067.7:g.167059702C>Tvariant
SNP
  • intron variant
NC_000067.7:g.167059735C>Tvariant
SNP
  • intron variant
NC_000067.7:g.167068224G>Cvariant
SNP
  • intron variant
NC_000067.7:g.167060091A>Gvariant
SNP
  • intron variant
NC_000067.7:g.167051129G>Tvariant
SNP
  • 3 prime UTR variant
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Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
Uck2em1(IMPC)J/Uck2em1(IMPC)J [background:] C57BL/6NJ-Uck2em1(IMPC)J/Mmjax
  • abnormal skin morphology
  • decreased mean corpuscular hemoglobin concentration
MGI
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Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
167.06M167.07M167.08M167.09M167.10M167.11MENSMUST00000027839 (Uck2)ENSMUST00000053686 (Uck2)ENSMUST00000191745 (Uck2)ENSMUST00000192269 (Uck2)ENSMUST00000192702 (Uck2)ENSMUST00000193579 (Uck2)ENSMUST00000195443 (Uck2)NM_001417919.1 (Uck2)NM_001417920.1 (Uck2)NM_001417921.1 (Uck2)Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.Maximum features displayed. See full view for more.

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

5 interactor genes based on 7 annotations
Uck2 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
RNA
Atg5Mus musculus
protein
  • affinity chromatography technology
PMID:35449600
protein
FynMus musculus
protein
  • two hybrid
PMID:15102471
protein
Grb2Mus musculus
protein
  • two hybrid
PMID:15102471
protein
Grb2Mus musculus
protein
  • two hybrid
PMID:15102471
protein
Grb2Mus musculus
protein
  • two hybrid
PMID:15102471
protein
OTUD4Homo sapiens
protein
  • pull down
PMID:31138677
protein
Wdtc1Mus musculus
protein
  • affinity chromatography technology
PMID:27113764
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Genetic Interactions

No data available